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Traditional Chinese medicine preparation and its preparation method and use

A technology of traditional Chinese medicine preparation and weight ratio, which is applied in the direction of medical formula, drug combination, medical preparations containing active ingredients, etc., can solve the problems of dependence, achieve low cost, inhibit inflammatory cell exudation, and relieve pain Effect

Active Publication Date: 2016-11-02
HANGZHOU NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current treatment for radiation pneumonitis is mainly the use of adrenal cortex hormones, which have a strong anti-inflammatory effect, but long-term use of hormones will lead to dependence on them and cause greater side effects

Method used

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  • Traditional Chinese medicine preparation and its preparation method and use
  • Traditional Chinese medicine preparation and its preparation method and use
  • Traditional Chinese medicine preparation and its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Astragalus 30g, Nansha ginseng 30g, Beisha ginseng 30g, Lily 10g, Dendrobium 10g, Aster 15g, Loquat leaf 20g, Bitter almond 12g, Baibu 15g, Angelica 18g.

[0033] Preparation method: Mix the components according to the formula, add 3 times the weight of water to soak for 20 minutes, cook at 120°C for 20 minutes, then adjust to 80°C and cook for 20 minutes, filter, repeat the filter cake, cook once, filter, and combine The filtrate was concentrated under reduced pressure (0.097Mpa, 50-60° C.) to 1.5 times the volume to obtain a decoction with a crude drug concentration of 2 g / ml.

Embodiment 2

[0035] Astragalus 30g, Nansha ginseng 25g, Beisha ginseng 25g, Lily 15g, Dendrobium 10g, Aster 15g, Loquat leaf 15g, Bitter almond 15g, Baibu 15g, Angelica 15g.

[0036] Preparation method: Mix the components according to the formula, add 4 times the weight of water to soak for 20 minutes, decoct at 120°C for 20 minutes, then adjust to 80°C for 20 minutes, filter, repeat the decoction of the filter cake once, filter, and combine the filtrate Concentrate under reduced pressure (0.097Mpa, 50-60° C.) to double the volume to obtain a decoction with a crude drug concentration of 2 g / ml.

Embodiment 3

[0038] Astragalus 30g, Nansha ginseng 30g, Beisha ginseng 30g, Lily 15g, Dendrobium 10g, Aster 15g, Loquat leaf 15g, Bitter almond 15g, Baibu 15g, Angelica 15g.

[0039]Preparation method: Mix the components according to the formula, add 3.5 times the weight of water to soak for 20 minutes, decoct at 120°C for 20 minutes, then adjust to 80°C for 20 minutes, filter, repeat the decoction of the filter cake once, filter, and combine the filtrate Concentrate under reduced pressure (0.097Mpa, 50-60° C.) to 1.8 times the volume to obtain a decoction with a crude drug concentration of 2 g / ml.

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Abstract

The invention discloses a traditional Chinese medicine preparation and its preparation method and use. The traditional Chinese medicine preparation is prepared from 20-30 parts by weight of radix astragali, 20-30 parts by weight of ladybell root, 20-30 parts by weight of glehnia root, 10-20 parts by weight of lily, 5-15 parts by weight of dendrobium, 10-20 parts by weight of tatarian aster root, 10-20 parts by weight of loquat leaves, 10-20 parts by weight of bitter apricot kernels, 10-20 parts by weight of radix stemonae and 10-20 parts by weight of radix angelicae sinensis. The traditional Chinese medicine preparation has effects of clearing lung-heat, relieving cough, calming panting, tonifying qi and yin and invigorating blood circulation. After eating, the traditional Chinese medicine preparation can directly act on a radiation pneumonitis diseased region, inhibit cell wall apillaritis cell infiltration, pulmonary interstitial hyperemia, bleeding, edema and alveolar structure damage, and reduce TLR4 signal transduction pathway signal molecule protein and local lung tissue related cell cytokine expression so that lung inflammation is relieved and radiation pneumonitis is delayed or treated.

Description

(1) Technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation and its preparation and application in preventing and treating radiation pneumonitis. (2) Background technology [0002] The incidence of lung cancer and other thoracic malignant tumors is increasing year by year, becoming one of the important factors that endanger health. Radiation therapy is one of the important treatment methods. Radiation pneumonitis is a common complication after radiotherapy for thoracic malignant tumors, with an incidence rate of 5% to 15%, often causing serious clinical consequences. Mild cases have no obvious symptoms, and severe cases can cause extensive pulmonary fibrosis, respiratory dysfunction, and even respiratory failure. [0003] The current treatment for radiation pneumonitis is mainly the use of adrenal cortex hormones, which have powerful anti-inflammatory effects, but long-term use o...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P11/00
CPCA61K9/0095A61K36/23A61K36/232A61K36/28A61K36/342A61K36/481A61K36/73A61K36/736A61K36/8967A61K36/8984A61K36/904A61K2236/331A61K2236/39A61K2300/00
Inventor 黄常新鲍艳红雷艳敏
Owner HANGZHOU NORMAL UNIVERSITY
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