Hollow stent for inducing regeneration and moulding of cartilage/bone tissues

Abstract

The invention relates to a hollow stent for inducing the regeneration and moulding of cartilage / bone tissues. The structure of the stent comprises an overall three dimensional hollow structure; and a plurality of holes in the surface. The hardness should meet the requirements of cartilage / bone tissues in the repaired parts. The stent should have a good biocompatibility and is made of a biologically degradable material. The biologically degradable material can be made into filling and repairing materials such as artificial auricular cartilage stents, artificial nose bridges, and the like, and can also be made into artificial bone stents with various sizes. The prepared stents with special structures can be combined with cultured cartilage / bone cells in vitro and then implanted into human body. Or, small cartilage blocks and cartilage sheets are filled into the hollow stents. The stents can be implanted into human body at first, and then cartilage / bone cells are injected into the stents. The inoculated cartilage / bone cells proliferate and pass down in the hollow three-dimensional stents, bones or cartilage tissues with the shape of the stents gradually form during the period, and tissues with similar functions and shapes can be obtained.

Description

technical field [0001] The invention relates to the technical field of cartilage / bone tissue engineering, in particular to a hollow support for inducing regeneration of cartilage / bone tissue. Background technique [0002] The emergence of tissue engineering in recent years has provided a new way for the repair of tissue defects. Bone / cartilage tissue engineering has been studied more in the field of tissue engineering. At present, the research focus of bone / cartilage tissue engineering is mainly on scaffold materials, such as Raw materials, biocompatibility, spatial structure, mechanical properties, etc. of the scaffold. The clinical application of bone / cartilage scaffolds is common in orthopedics and orthopedics, but with the increase of applications, there are many shortcomings. For example, in orthopedics, the clinically used assembled artificial ear cartilage scaffold Medpor repairs microtia, although It solves the extra damage and pain of cutting the costal cartilage f...

AI Technical Summary

Problems solved by technology

The clinical application of bone / cartilage scaffolds is common in orthopedics and orthopedics, but with the increase of applications, there are many shortcomings. For example, in orthopedics, the clinically used assembled artificial ear cartilage scaffold Medpor repairs microtia, although It solves the extra damage and pain of cutting the costal cartilage from the autologous body and the cumbersome process of carving the autologous costal cartilage, but the artificial cartilage is made of polyethylene material, which has high hardness and insufficient elasticity, which may easily lead to exposure of the bracket, etc.