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Miao medicine preparation for treating osteoarticular diseases and preparation method and application thereof

A technology for bone and joint diseases and external preparations, which are used in bone diseases, pharmaceutical formulations, nervous system diseases, etc.

Inactive Publication Date: 2016-10-12
王福宁 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The threat of bone and joint diseases to human beings is increasing rapidly. However, for a long time, the research and treatment of bone and joint diseases have not been able to find a truly effective method

Method used

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  • Miao medicine preparation for treating osteoarticular diseases and preparation method and application thereof
  • Miao medicine preparation for treating osteoarticular diseases and preparation method and application thereof
  • Miao medicine preparation for treating osteoarticular diseases and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] A Wangfuling Miao medicine preparation, in parts by weight, is made from the following raw materials: 1 part of Angelica sinensis, 1 part of saffron, 1 part of Chuanqiong, 1 part of Eucommia ulmoides and 1 part of Xueteng. Weigh angelica, saffron, Chuanqiong, Eucommia ulmoides and Xueteng according to the weight ratio, wash with water, dry in the shade, and slice; mix the raw materials of the slices and add 20% ethanol solution according to the mass ratio. Medicine: ethanol solution=1:6; heat and reflux for 3 times at 20°C, extract for 3 hours each time, filter, combine the extracts to obtain the medicinal solution, maintain the volume concentration of ethanol in the medicinal solution at 40%, and take 0.5 mL of the medicinal solution. Under 1cm 2 The patch can be obtained on the medicine pad. The medicinal pad is a commercially available product.

Embodiment 2

[0128] A Wangfuling Miao medicine preparation, in parts by weight, is made of the following raw materials: 7 parts of Angelica sinensis, 3 parts of Saffron, 4 parts of Chuanqiong, 3 parts of Eucommia ulmoides and 3 parts of Xueteng. Weigh Angelica sinensis, Saffron, Chuanqiong, Eucommia ulmoides and Xueteng according to weight ratio, wash with water, dry in the shade, and slice; mix the sliced ​​raw materials and add 90% ethanol solution according to the mass ratio, and mix the raw materials Medicine: ethanol solution=1:20; heat and reflux at 95℃ to extract once, extract 0.5h each time, filter, combine the extracts to obtain the drug solution, maintain the volume concentration of ethanol in the drug solution at 60%, and take 2mL drops of the drug solution Under 5cm 2 The patch can be obtained on the medicine pad. The medicinal pad is a commercially available product.

Embodiment 3

[0130] A Wangfuling Miao medicine preparation is made from the following raw materials in parts by weight: 4 parts of Angelica sinensis, 2 parts of Saffron, 3 parts of Chuanqiong, 2 parts of Eucommia ulmoides and 2 parts of Xueteng. Weigh angelica, saffron, Chuanqiong, Eucommia ulmoides and Xueteng according to the weight ratio, wash with water, dry in the shade, and slice. The thickness of the sliced ​​API is 0.5cm; the volume fraction of the sliced ​​API is 60% after mixing. According to the mass ratio, the mixed API: ethanol solution=1:12; heat reflux for extraction twice at 60°C, extract 2h each time, filter, combine the extracts to obtain the drug solution, maintain the volume of ethanol in the drug solution The concentration is 50%, take 1mL of the drug solution and drop it on 3cm 2 The patch can be obtained on the medicine pad.

[0131] Among them, the applicator pad is prepared by the following method: uniformly spread the glue on the non-woven fabric, heat to volatilize ...

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Abstract

The invention discloses a Miao medicine preparation for treating osteoarticular diseases. The Miao medicine preparation is prepared from the following raw medicinal materials in parts by weight: 1 to 7 parts of radix angelicae sinensis, 1 to 3 parts of stigma saffron crocus, 1 to 4 parts of rhizoma Chuanxiong, 1 to 3 parts of cortex eucommiae and 1 to 3 parts of caulis sargentodoxae. The invention further discloses a preparation method of the Miao medicine preparation. The Miao medicine preparation for treating osteoarticular diseases provided by the invention can be used for effectively treating the osteoarticular diseases. The Miao medicine preparation for treating osteoarticular diseases has the effects of remarkably reducing the IL-1beta(Interleukin-1beta) expression and TNF-alpha(Tumor Necrosis Factor-alpha) expression, thereby restricting inflammatory response and protecting cartilage tissues. The Miao medicine preparation disclosed by the invention can be used for effectively treating cervical spondylosis, has a better curative effect and has the efficacies of tonifying the liver and kidney, strengthening tendons and bones, dispelling wetness and wind and promoting blood circulation to remove meridian obstruction, and can also be used for restricting neuropathic pain. The preparation method disclosed by the invention is simple and easy to operate, mild in conditions, easy to control, short in preparation time, low in cost and easy for large-scale production.

Description

Technical field [0001] The invention relates to a Wangfuling Miao medicine preparation and a preparation method and application thereof, in particular to the technical field of Miao medicine. Background technique [0002] In the age of inconvenient transportation, Miao people living in mountainous areas have to bear heavy burdens over the mountains, working in the fields all the year round, and women embroidering for a long time, causing many patients with cervical, lumbar and knee joint injuries to varying degrees. Cervical spondylosis is a syndrome of a series of clinical symptoms caused by cervical disc degeneration and cervical bone hyperplasia. It can occur at any age. In recent years, many young people and even elementary and middle school students have also contracted this type of disease, and the age of onset has obviously tended to be younger. Cervical spondylosis is an occupational disease with high incidence and long treatment time, and it is easy to relapse after tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/70A61P19/02A61P19/08A61P25/00A61P29/00
CPCA61K9/7023A61K36/232A61K36/236A61K36/46A61K36/57A61K36/79A61K36/88A61K2236/333A61K2236/39A61K2300/00
Inventor 王福宁汪浩秦春耀
Owner 王福宁
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