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Traditional Chinese medicine composition for treating depression insomnia

A technology for insomnia and composition, which is applied in the field of traditional Chinese medicine composition for the treatment of depressive insomnia, which can solve problems such as dependence on western medicine and difficult treatment of depressive insomnia, and achieve extensive pharmacological effects, calming the mind and tranquilizing the mind, and improving sleep Effect

Active Publication Date: 2016-10-12
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The purpose of the present invention is to provide a kind of traditional Chinese medicine preparation specially for the treatment of depressive insomnia, solve the problem that depressive insomnia is difficult to treat at present, and use western medicine to cause dependence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A traditional Chinese medicine composition for treating depressive insomnia, the raw materials thereof include 45 parts of Jujube seed extract and 30 parts of Albizia Julibrissin flower extract in parts by weight.

[0036] The preparation method of jujube seed extract comprises the following steps:

[0037] 1) Crush the spiny seed kernel and pass through a 80-mesh sieve to get the spiny date seed powder. According to the amount of water that is 3 times the weight of the spiny date kernel powder, add water to soak the spiny date kernel powder. / 60 combined enzyme reagent for enzymolysis treatment, the enzymolysis temperature is controlled at 40°C, and the enzymolysis time is 4 hours;

[0038] 2) Add an ethanol solution with a volume concentration of 70% to the jujube seed solution after enzymolysis in step 1 according to the amount of ethanol solution that is twice the weight of the jujube seed powder, and perform ultrasonic extraction. The power of the ultrasonic wave i...

Embodiment 2

[0047] A traditional Chinese medicine composition for treating depressive insomnia, the raw materials thereof include 30 parts of Jujube Seed Extract and 45 parts of Albizia Julibrissin Flower Extract in parts by weight.

[0048] The preparation method of jujube seed extract comprises the following steps:

[0049] 1) Crush the spiny seed kernels and pass through a 80-mesh sieve to get the spiny date seed powder. According to the amount of water that is 4 times the weight of the spiny jujube kernel powder, add water to soak the spiny date kernel powder. The soaking time is 13 minutes, and then add 1 / 55 combined enzyme reagent for enzymolysis treatment, the enzymolysis temperature is controlled at 45°C, and the enzymolysis time is 3 hours;

[0050] 2) Add an ethanol solution with a volume concentration of 75% to the jujube seed solution after the enzymolysis in step 1, according to the amount of ethanol solution that is twice the weight of the jujube kernel powder, and perform ...

Embodiment 3

[0059] A traditional Chinese medicine composition for treating depressive insomnia, the raw materials thereof include 60 parts of Jujube seed extract and 60 parts of Albizia Julibrissin flower extract in parts by weight.

[0060] The preparation method of jujube seed extract comprises the following steps:

[0061] 1) Crush the spiny seed kernel and pass through a 80-mesh sieve to get the spiny date seed powder. According to the amount of water that is 5 times the weight of the spiny date seed powder, add water to soak the spiny date kernel powder. / 50 combined enzyme reagent for enzymolysis treatment, the enzymolysis temperature is controlled at 50°C, and the enzymolysis time is 2 hours;

[0062]2) Add an ethanol solution with a volume concentration of 80% to the jujube seed solution after the enzymolysis in step 1, according to the amount of ethanol solution that is twice the weight of the jujube seed powder, and perform ultrasonic extraction. The power of the ultrasonic wave...

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Abstract

The invention provides traditional Chinese medicine composition for treating depression insomnia. The traditional Chinese medicine composition is prepared from 30-60 parts by weight of spina date seed extract and 30-60 parts by weight of albizia flower extract, wherein the content of saponin in the spina date seed extract is larger than or equal to 85.0%, and saponin has effects of heart nourishing, mind tranquilizing, sedation, hypnosis, arrhythmia resistance and myocardial ischemia resistance, has certain pressure reduction effect and is one of main components with sedative and hypnotic effects, thereby having quite good effect of improving sleep; the total flavonoid content of the albizia flower extract is larger than or equal to 35%, and flavonoid compounds have effects of depression resistance, anxiety resistance, scavenging of hydroxyl radicals and the like and has significant pharmacological activity in aspects of treatment of depression, schizophrenia, cancer and the like. Therefore, spina date seeds and albizia flowers in the formula form a medicine pair, the composition is simple, convenient, effective and economic, has functions of soothing the liver, relieving depression, tranquilizing mind, regulating qi and harmonizing the stomach, and is used for treating emotional disorder, depression insomnia, chest distress, anorexia and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating depressive insomnia. Background technique [0002] Depressive insomnia (DI) is one of the most common clinical symptoms in the dry or middle-late stage of depression and dysthymia. Falling asleep, dreaming; some unpleasant past events repeatedly appear in the mind, or worry about the future, one's own body, etc.; no sense of clarity and energy after waking up in the morning; dizziness, fatigue, weakness or falling asleep during the day; mood and interest Depression is the most significant and common symptom of depressive insomnia, accompanied by impaired cognitive function, decreased ability to work and study, decreased memory, and inability to concentrate. It can cause troubles to patients' study, work, life, etc., and even frequently lead to accidents. At present, it has attracted the attention of c...

Claims

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Application Information

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IPC IPC(8): A61K36/725A61P25/20A61P25/24
CPCA61K36/48A61K36/725A61K2236/19A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 施学丽郭超峰冯秋瑜李曼菲臧知明
Owner GUANGXI UNIV OF CHINESE MEDICINE
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