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Traditional Chinese medicine composition for treating fatty liver and preparation method and use thereof

A composition and fatty liver technology, applied in the field of medicine, can solve problems such as high price and unclear active ingredients

Inactive Publication Date: 2016-09-14
THE AFFILIATED HOSPITAL OF TRADITIONAL CHINESE MEDICAL TO SOUTHWEST MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many kinds of drugs clinically used to prevent and treat fatty liver and hyperlipidemia, with broad prescriptions, unclear medicinal ingredients, and high prices

Method used

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  • Traditional Chinese medicine composition for treating fatty liver and preparation method and use thereof
  • Traditional Chinese medicine composition for treating fatty liver and preparation method and use thereof
  • Traditional Chinese medicine composition for treating fatty liver and preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 Chinese medicine composition granule of the present invention

[0025] Weigh the raw materials according to the following ratio:

[0026] Hawthorn 300g, Salvia 400g, Chenpi 240g, Codonopsis 300g, Alisma 200g, Puhuang 300g, Curcuma 300g.

[0027] The preparation method is as follows:

[0028] a. Participate in 5 times the amount of 60% ethanol and soak for 7 days, filter, recover the ethanol from the medicinal solution, concentrate it into a liquid extract, and set aside;

[0029] b. Soak medicinal dregs, Codonopsis pilosula, Alisma, hawthorn, tangerine peel, Puhuang, and turmeric in 7 times the amount of water for 0.5 hours, decoct twice, 1 hour each time, collect volatile oil at the same time, and set aside; combine the decoction and filter , the filtrate was concentrated under reduced pressure to a relative density of 1.02-1.05 (80°C), left to stand for 12 hours, filtered, the filtrate was concentrated under reduced pressure to a rela...

Embodiment 2

[0031] The preparation of embodiment 2 Chinese medicine composition of the present invention

[0032] Weigh the raw materials according to the following ratio:

[0033] Hawthorn 150g, Danshen 250g, Chenpi 90g, Codonopsis 150g, Alisma 50g, Puhuang 150g, Curcuma 150g.

[0034] The preparation method is as follows:

[0035] Soak each raw material in the Chinese medicine composition with water for 30 minutes, add 8 times the amount of water to decoct and extract, decoct 3 times, each time for 1 hour, filter, combine the extracts, concentrate, add pharmaceutically acceptable adjuvants or auxiliary The ingredients are formulated as a powder.

Embodiment 3

[0036] The preparation of embodiment 3 Chinese medicine composition of the present invention

[0037] Weigh the raw materials according to the following ratio:

[0038] Hawthorn 450g, Salvia miltiorrhiza 550g, Chenpi 390g, Codonopsis 450g, Alisma 350g, Puhuang 450g, Curcuma 450g.

[0039] The preparation method is as follows:

[0040] Crush and mix the raw materials in the traditional Chinese medicine composition, add 55% v / v ethanol to soak for 60 minutes, add 10 times the amount of 55% v / v ethanol to reflux extraction, extract once, each time for 90 minutes, filter the extract, Concentrate, add pharmaceutically acceptable excipients or auxiliary components, and compress into tablets.

[0041] The beneficial effects of the present invention are demonstrated through specific experiments below.

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Abstract

The invention provides a traditional Chinese medicine composition for treating fatty liver, wherein the traditional Chinese medicine composition is prepared from the following raw materials by weight: 15-45 parts of hawthorn, 25-55 parts of salvia miltiorrhiza, 9-39 parts of pericarpium citri reticulatae, 15-45 parts of codonopsis pilosula, 5-35 parts of rhizoma alismatis, 15-45 parts of pollen typhae, and 15-45 parts of radix curcumae. The invention also provides a preparation method of the traditional Chinese medicine composition and a use of the traditional Chinese medicine composition in preparation of drugs for preventing and / or treating fatty liver and hyperlipemia. The prepared traditional Chinese medicine composition has the fatty liver treating clinical total effective rate of 93.33%, has the advantages of high efficiency, low cost, convenience, safety and the like, and provides a new scheme for preventing and / or treating fatty liver and hyperlipidemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating fatty liver, a preparation method and application thereof, and belongs to the field of medicines. Background technique [0002] Fatty liver is a metabolic disease and one of the most common diffuse liver diseases. It can be caused by the liver itself, or it can be the result of other diseases affecting fat metabolism. It mainly refers to the level of transaminase, globulin, triacyl Elevated glycerin and cholesterol. Traditional Chinese medicine believes that fatty liver is mostly caused by liver failure, liver blood stasis, spleen failure, stagnation of dampness, endogenous phlegm dampness, phlegm turbidity and blood stasis, and accumulation in the liver. It should be based on drying dampness and resolving phlegm, promoting blood circulation and removing blood stasis, supplemented by invigorating the spleen and replenishing qi, nourishing the kidney and liver. [0003] H...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61P3/06
CPCA61K36/734A61K36/344A61K36/537A61K36/752A61K36/88A61K36/884A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 孙同郊汪静杨华秀谢朝良魏嵋刘鹏米绍平张光海
Owner THE AFFILIATED HOSPITAL OF TRADITIONAL CHINESE MEDICAL TO SOUTHWEST MEDICAL UNIV
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