Mass spectrum ion source device

Abstract

The invention relates to a mass spectrum ion source device. The mass spectrum ion source device comprises a point electrode, an insulating medium, a power supply, an instrument interface and a gas conduct; the insulating medium is located between the point electrode and the instrument interface; a tip part of the point electrode is contacted with the insulating medium, and the other end of the point electrode is connected with the power supply; the instrument interface is grounded and connected with the other end of the power supply; a strong electric field is formed between the point electrode and the instrument interface; discharge gases are filled between the insulating medium and the instrument interface through the gas conduit, and a plasma beam is formed under the action of the strong electric field; and the plasma beam interacts with an object to be measured on the surface of the insulating medium to ionize the object to be measured, so as to realize analysis and detection. The mass spectrum ion source device provided by the invention has the advantages of being simple in structure, low in cost, no solvent and high in flux and so on, besides, a linear electric field formed by the point electrode and the instrument interface improves the transmission efficiency of ions. Moreover, the mass spectrum ion source device can also be used for mass spectrometry imaging analysis.

Description

technical field [0001] The invention relates to a mass spectrometer ion source device, in particular to a dielectric barrier discharge mass spectrometer ion source device. It is also a high-sensitivity, high-resolution mass spectrometry imaging ion source device. Background technique [0002] Ion sources are the core components of mass spectrometers. In recent years, the development and application of atmospheric pressure open ionization mass spectrometry technology that realizes ionization in an open environment has become a frontier and hot spot in the field of mass spectrometry. On the basis of desorption electrospray (DESI) and real-time direct analysis (DART), atmospheric pressure open ion sources have rapidly developed into two types based on electrospray droplets and plasma substances. In 2007, Zhang Xinrong et al. disclosed a dielectric barrier discharge atmospheric ionization source (DBDI) for sample analysis or imaging. Its main structure includes: barrier medium,...

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Problems solved by technology

However, each method has its own limitations. For example, DESI uses high-pressure gas to drive the sample ions to move, so that the sample ion beam far exceeds the entrance of the mass spectrometer, so that some sample ions cannot enter the mass spectrometer and be detected; LTP not only has a complex electrode structure, but also The use of discharge gas to drive target ions leads to a decrease in sensitivity; the spatial resolution of DESI and LTP imaging techniques is not high enough to balance sample desorption rate and sensitivity

In addition, the ions analyzed by this type of ion source cannot directly enter the mass spectrometer, but enter the mass spectrometer at a certain angle, and the low-efficiency ion transmission

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