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Head-wearing OCT (optical coherence tomography) imaging system for free moving animal

A technology of optical coherence tomography and imaging system, applied in the field of head-mounted optical coherence tomography imaging system, can solve the problems of equipment miniaturization and imaging equipment for free-moving animals, and achieve equipment miniaturization and ingenious structure and compact effect

Active Publication Date: 2016-08-10
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As an emerging brain structure and function imaging technology, optical coherence tomography can realize three-dimensional brain structure and function imaging, but due to the difficulty of miniaturization of equipment (such as the need for stepping motors for two-dimensional scanning control, etc.), There are currently no imaging devices available for freely moving animals

Method used

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  • Head-wearing OCT (optical coherence tomography) imaging system for free moving animal
  • Head-wearing OCT (optical coherence tomography) imaging system for free moving animal
  • Head-wearing OCT (optical coherence tomography) imaging system for free moving animal

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Embodiment Construction

[0025] Figure 1 ~ Figure 3 A specific embodiment of the head-mounted optical coherence tomography system of the present invention is shown, and the system mainly includes a base 1 , a bracket 2 , an optical fiber 3 , a focusing lens 4 and a MEMS scanning mirror 5 .

[0026] A vertically penetrating circular through hole is formed on the base 1, and the circular through hole forms a light transmission channel capable of transmitting light.

[0027] The bracket 2 is detachably fixed on the upper part of the base 1, and its upper and lower ends and one side are all open structures. Moreover, the support 2 is provided with a circular optical fiber insertion hole 8 and a circular card slot, and the hole wall of the optical fiber insertion hole 8 is vertically provided with a screw hole for passing a screw. The detachable transfer structure between the bracket 2 and the base 1 is specifically: the upper part of the base 1 is provided with a circular protrusion corresponding to the...

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Abstract

The invention discloses a head-wearing OCT (optical coherence tomography) imaging system for a free moving animal, which comprises a base, a bracket, an optical fiber for conducting light, a focusing lens and an MEMS (Micro Electro Mechanical System) scanning mirror, wherein the base is provided with a light transmission channel vertically arranged in an extending manner; the bracket is fixed at the upper part of the base in a detachable manner; one end of the optical fiber is connected with an external OCT system and the other end of the optical fiber is connected to the bracket; the focusing lens is fixed on the bracket and is positioned above the light transmission channel; the MEMS scanning mirror is mounted on the bracket and can reflect the light conducted by the optical fiber from the external OCT system to the position of the focusing lens. The imaging system is light and small in body form, can be worn at the head of the animal, can implement clear cortex structure and function imaging in a free motion state, and the head-wearing OCT imaging system for the free moving animal appears for the first time in a current OCT imaging technology in the application field.

Description

technical field [0001] The invention relates to the field of optical imaging, in particular to a head-mounted optical coherence tomography system for freely moving animals. Background technique [0002] Optical coherence tomography (OCT) is a three-dimensional optical imaging technology with high temporal and spatial resolution, which can realize micron-scale tomographic structure and functional imaging of biological tissues. The basis of optical coherence tomography technology is Michelson interferometer. The laser light source is broad-spectrum light with low coherence characteristics. Depth information, and then use optical scanning equipment to perform two-dimensional scanning to obtain three-dimensional image information. Due to its technical advantages, it has applications in ophthalmic diseases, skin tissue detection, cardiovascular, oral cavity, early diagnosis of cancer, etc. OCT has also been combined with endoscopic technology to achieve non-destructive high-reso...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
CPCA61B5/0066A61B5/4064A61B5/6814A61B5/6832A61B2503/40A61B2503/42
Inventor 童善保陆晓丹李瑶
Owner SHANGHAI JIAO TONG UNIV
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