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Pharmaceutical composition for preventing and/or treating parasites and its preparation method and application

A composition and parasite technology, applied in pharmaceutical applications, in the field of pharmaceutical compositions for preventing and/or treating pet parasitic diseases, can solve problems such as animal injury, hair follicle damage, skin ulceration, etc., and achieve safety High, smooth fur, promotes repair and healing effect

Active Publication Date: 2019-09-17
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It mainly reaches the whole body through the sebaceous glands of animals to play a role. Although normal medication is not easily absorbed by the blood, when animals are infected with fleas, ticks and other body parasites, symptoms such as skin ulcers and hair follicle damage will occur due to bites. During the drug process, the drug will still enter the blood vessel with the broken wound, causing harm to the animal

Method used

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  • Pharmaceutical composition for preventing and/or treating parasites and its preparation method and application
  • Pharmaceutical composition for preventing and/or treating parasites and its preparation method and application
  • Pharmaceutical composition for preventing and/or treating parasites and its preparation method and application

Examples

Experimental program
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Effect test

Embodiment 1

[0035] Embodiment 1: Preparation Example 1

[0036] Prescription: 5% fiprenil, 4% methoprene, 2% acetylated lanolin, tween-805%, 10% ethanol, 5% purified water and the balance of diethylene glycol monoethyl ether.

[0037] Preparation method: Weigh 5.211g of fiprenil and 2.033g of acetylated lanolin, put them in a clean container, add 50ml of diethylene glycol monoethyl ether, and stir to dissolve. Add 4.507g of methoprene and 5.137g of Tween-805.137g, and stir to dissolve. Add 5ml of purified water, add diethylenedimonoethyl ether to 100ml, stir evenly, and package to obtain a light yellow clear liquid with a relative density of 1.018.

Embodiment 2

[0038] Embodiment 2: Preparation Example 2

[0039] Prescription: 10% fiprenil, 9% methoprene, 3% lanolin, Tween-805%, 10% ethanol, 5% purified water and the balance of diethylene glycol monoethyl ether.

[0040] Preparation method: Weigh 10.265g of fiprenil and 3.051g of lanolin alcohol, put them in a clean container, add 50ml of diethylene glycol monoethyl ether, and stir to dissolve. Add 9.035g of methoprene and 805.124g of Tween, and stir to dissolve. Add 5ml of purified water, add diethylenedimonoethyl ether to 100ml, stir evenly, and package to obtain a light yellow clear liquid with a relative density of 1.025.

Embodiment 3

[0041] Embodiment 3: Preparation Example 3

[0042] Prescription: 20% of fiprenil, 18% of methoprene, 4% of acetylated lanolin, 805% of Tween, 10% of ethanol, 5% of purified water and the balance of diethylene glycol monoethyl ether.

[0043] Preparation method: Weigh 20.158g of fiprenil and 4.133g of lanolin alcohol, put them in a clean container, add 30ml of diethylene glycol monoethyl ether, and stir to dissolve. Add 18.365 g of methoprene and 805.036 g of Tween, and stir to dissolve. Add 5ml of purified water, add diethylenedimonoethyl ether to 100ml, stir evenly, and package to obtain a light yellow clear liquid with a relative density of 1.037.

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Abstract

The present invention relates to a parasite prevention and / or treatment pharmaceutical composition, and the pharmaceutical composition comprises the following components: 5-20% of Fipronil, 4-18% of methoprene, 2-10% of an emollient, and the balance of a pharmaceutically acceptable carrier. The present invention also relates to a preparation method and application of the pharmaceutical composition in preparation of drugs for the prevention and / or treatment of pet diseases.

Description

technical field [0001] The invention relates to a pharmaceutical composition for preventing and / or treating pet diseases, in particular to a pharmaceutical composition for preventing and / or treating pet parasitic diseases. The invention also relates to the preparation method of the pharmaceutical composition and its application in the preparation of medicines for preventing and / or treating pet diseases. Background technique [0002] Parasitic diseases are one of the common diseases of pets, which seriously threaten the health of animals, not only affecting their production and development, but also creating conditions for the invasion of other pathogens. Especially ticks, mites, mosquitoes, fleas and other body parasites, in addition to injecting pathogens into animals through biting the skin, increasing the chance of infection in animals, the most direct damage to pets is to stimulate the animal skin, causing itching, making the animal constantly Scratching will cause dama...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/415A61P33/14A61P17/02A61P17/00A61K31/231
Inventor 张许科刘兴金高艳艳
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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