Traditional Chinese medicine composition and preparation thereof

A pharmaceutical preparation and a technology for the composition are applied in the field of traditional Chinese medicine compositions and their preparations for the treatment of chronic congestive heart failure, and can solve the problems of poor curative effect, multiple drug forbidden areas, limited clinical application and the like

Inactive Publication Date: 2016-06-01
FUWAI HOSPITAL OF CARDIOVASCULAR DESEASE CHINESE ACAD OF MEDICAL SCI
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are still many problems to be solved in western medicine treatment: if the clinical symptoms cannot be completely improved, the qua...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition and preparation thereof
  • Traditional Chinese medicine composition and preparation thereof
  • Traditional Chinese medicine composition and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] The preparation of embodiment 1 Chinese medicine composition granule of the present invention

[0093] Weigh the raw materials according to the following dosage: Astragalus 45g; Ginseng 10g; Salvia miltiorrhiza 30g; Sanleng 15g; 15g.

[0094] The preparation method is as follows:

[0095] (1) Take the raw materials of the above-mentioned consumption;

[0096] (2) Soak the above-mentioned raw materials with 8 times the volume of water for 1 hour;

[0097] (3) Decocting: after boiling, decoct for 2 hours;

[0098] (4) Filtration: add 6 times the amount of water, decoct for 1 hour, and combine the filtrate to filter;

[0099] (5) Concentration: vacuum decompression, the concentration pressure is -0.06 to -0.08MPa, and the temperature is 90°C;

[0100] (6) Drying and forming: spray drying and granulation, the pressure is -0.06 to -0.08MPa, and the temperature is 180°C. Each pack is 5g, containing 18.1g of crude drug.

[0101] Embodiment 2 The effect of the granule of...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a traditional Chinese medicine composition, which comprises the following ingredients (by weight): 25-65 parts of radix astragali, 0-20 parts of ginseng, 10-50 parts of red sage root, 5-25 parts of rhizoma sparganii, 20-40 parts of polygonum aviculare, 5-25 parts of black prepared lateral root of aconite, 5-25 parts of deerhorn glue, 10-50 parts of poria cocos, 5-25 parts of donkey-hide gelatin, 15-45 parts of spine date seed, 0-20 parts of semen arecae prepareta and 5-25 parts of honey-fried licorice root. In clinical application, the traditional Chinese medicine composition can obviously relieve clinical symptoms of patients with chronic congestive heart failure and raise exercise tolerance and living quality. In the long term, left ventricular end-diastolic diameter can be reduced, left ventricular ejection fraction (EF) of heart is raised, blood plasma NT-proBNP level and circulating endothelial cell number can be reduced, and rehospitalization frequency of patients is decreased. The traditional Chinese medicine composition has steady and lasting effects and has no obvious toxic or side effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating chronic congestive heart failure and its preparation. Background technique [0002] Heart failure is the terminal state of various heart diseases and the main cause of death in heart disease patients. In recent years, the incidence of heart failure has been increasing year by year. In the United States, the prevalence of heart failure in adults (>25 years old) is 1.5%-2.0%, and there are about 5 million patients, with an increase of 500,000-700,000 people every year. More than 400,000 people died of heart failure; in Europe, there are about 15 million patients with heart failure, the prevalence rate is 2%-3%, 40% of hospitalized patients with heart failure die within 1 year or need to be hospitalized again; in China, heart failure The incidence rate is 0.9%, that is, there are about 4 million heart failure patients among adults a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/902A61P9/04A61P29/00A61P9/10A61P9/12A61P9/06A61P9/00A61P11/00A61K35/32A61K35/36
Inventor 马丽红
Owner FUWAI HOSPITAL OF CARDIOVASCULAR DESEASE CHINESE ACAD OF MEDICAL SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap