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Pharmaceutical composition for treating polycystic ovarian syndrome with obesity

A polycystic ovary and composition technology, applied in the field of medicine, can solve problems such as gastrointestinal adverse reactions, lack of safe and effective methods, and poor long-term efficacy

Inactive Publication Date: 2016-05-25
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still no safe and effective method for the clinical treatment of obese PCOS. Ovulation induction, insulin sensitizers and anti-androgen therapy are the main methods of Western medicine, but there are still poor long-term curative effects, drug dependence, and gastrointestinal adverse reactions. limitation

Method used

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  • Pharmaceutical composition for treating polycystic ovarian syndrome with obesity
  • Pharmaceutical composition for treating polycystic ovarian syndrome with obesity
  • Pharmaceutical composition for treating polycystic ovarian syndrome with obesity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Embodiment 1 capsule

[0069] Prescription: 12 parts of Ligustrum lucidum, 20 parts of Cuscuta, 12 parts of water fennel, 15 parts of Pinellia chinensis, 12 parts of Motherwort, 16 parts of Laolaiqing, 15 parts of Rehmannia glutinosa, 10 parts of Acanthopanax, 12 parts of Liuyuexue, Cyperus 12 parts, licorice 6 parts.

[0070] Preparation method: (1) Extract water fennel, pinellia chinensis, motherwort, Lao Laiqing, and xiangfu with 70% ethanol twice, each time for 1.5-2.0 hours, collect ethanol extract and ethanol extract filter residue, concentrate under reduced pressure Dried extract, freeze-dried, and crushed to obtain ethanol extract;

[0071] (2) Combine the ethanol extracts of Ligustrum lucidum, Cuscuta, Rehmannia glutinosa, Acanthopanax, Junixue, licorice and fennel, Pinellia chinensis, motherwort, lanorrhea, Cyperus cyperus ethanol extracts, add water and decoct twice, Combine the decoctions, filter, concentrate the filtrate under reduced pressure to a relati...

Embodiment 2

[0074] Embodiment 2 capsules

[0075]Prescription: 10 parts of Ligustrum lucidum, 20 parts of Cuscuta, 10 parts of water fennel, 12 parts of Pinellia chinensis, 10 parts of Motherwort, 18 parts of Laolaiqing, 12 parts of Rehmannia glutinosa, 10 parts of Acanthopanax, 15 parts of Liuyuexue, Cyperus 12 parts, licorice 5 parts.

[0076] Preparation method: with reference to Example 1.

Embodiment 3

[0077] Embodiment 3 capsules

[0078] Prescription: 15 parts of Ligustrum lucidum, 22 parts of Cuscuta, 15 parts of water fennel, 10 parts of Pinellia chinensis, 15 parts of Motherwort, 18 parts of Laolaiqing, 12 parts of Rehmannia glutinosa, 8 parts of Acanthopanax, 17 parts of Liuyuexue, Cyperus 15 parts, licorice 6 parts.

[0079] Preparation method: with reference to Example 1.

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Abstract

The invention belongs to the technical field of medicines, and relates to a pharmaceutical composition for treating a polycystic ovarian syndrome with obesity and a preparation method thereof. The pharmaceutical composition is carefully prepared from fructus ligustri lucidi, semen cuscutae, radix rehmanniae preparata, radix et caulis acanthopanacis senticosi, herba leonuri, all-grass of winkled marshweed, rhizoma pinelliae preparatum, roots of boerhaavia diffusa L., herba serissa serissoides (DC.) druce, rhizoma cyperi and licorice roots. According to the pharmaceutical composition, the effects of tonifying the liver and the kidney, activating blood circulation to dissipate blood stasis, eliminating dampness and phlegm and regulating menstruation and the blood are achieved, it is prompted through clinical observation experiment results that the pharmaceutical composition for treating the polycystic ovarian syndrome with the obesity can significantly relieve the clinical symptom, the internal secretion and hormonal level of a patient are adjusted, ovulation is facilitated, and new ideas and effective methods are provided for clinically treating the polycystic ovarian syndrome with the obesity.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a pharmaceutical composition for treating polycystic ovary syndrome with obesity and a preparation method thereof. Background technique [0002] Polycystic ovary syndrome (Polycysticovariansyndrome, PCOS) is a common clinical endocrine disorder syndrome, and the clinical manifestations are the coexistence of reproductive dysfunction and abnormal glucose metabolism. Clinical manifestations include abnormal menstruation (most patients show oligomenorrhea or amenorrhea, and a few can show frequent menstruation or regular menstruation), hirsutism, obesity, acanthosis nigricans and other manifestations. Related studies have shown that the incidence of this disease in women of childbearing age is as high as 5% to 10%, while the incidence of obesity in PCOS patients is 41% to 50%. [0003] At present, a large number of studies have been done on PCOS, and its basic characteristics are mo...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P5/00A61P15/00A61P3/04
CPCA61K36/638A61K36/02A61K36/185A61K36/254A61K36/28A61K36/282A61K36/39A61K36/41A61K36/47A61K36/484A61K36/533A61K36/74A61K36/804A61K36/8888A61K36/8905A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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