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Composition containing alkannin and lemon grass essential oil

A technology of lemongrass essential oil and composition, which is applied in the field of biomedicine and therapeutic cosmetics, can solve the problems of lack of safety limit regulations, combined application of shikonin and lemongrass essential oil, and hidden dangers, so as to promote rapid healing , promote wound healing, good safety effect

Inactive Publication Date: 2016-05-18
南京紫源康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As the key technology for preparing high-purity shikonin has not yet been industrialized, domestic new drug products using shikonin as raw materials have not yet officially entered the market. The 2010 edition of the Chinese Pharmacopoeia still contains some varieties containing PAs but lacking safety limit regulations , which also includes comfrey, leaving hidden dangers for clinical application
There is no report on the combined application of shikonin and lemongrass essential oil

Method used

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  • Composition containing alkannin and lemon grass essential oil
  • Composition containing alkannin and lemon grass essential oil
  • Composition containing alkannin and lemon grass essential oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 A kind of composition and ointment with antibacterial and anti-inflammatory effect

[0021] Formula ingredients (100g): shikonin 0.05g, lemongrass essential oil 1.80g, white petrolatum 3.0g, stearyl alcohol 2.0g, light liquid paraffin 7.0g, glycerin 8.0g, glyceryl monostearate 3.0g, hard Fatty acid 6.0g, triethanolamine 0.3g, deionized water added to 100g.

[0022] Preparation method: Mix shikonin, stearic acid, glyceryl monostearate, white petrolatum, stearyl alcohol, and light liquid paraffin, heat in a water bath at 70-80°C, melt, stir evenly, and make oil Phase A: Dissolve glycerin and triethanolamine in deionized water, heat in a water bath at 70-80°C, and stir evenly to form aqueous phase B. Pump A and B into a homogenizing pot, keep a constant temperature of 70-80°C and homogenize. After being fully emulsified, stir and gradually cool to 45°C, add lemongrass essential oil to cool to room temperature, and fill to obtain an ointment.

Embodiment 2

[0023] Embodiment 2 A kind of composition and face cream with antibacterial and anti-inflammatory effect

[0024] Formula ingredients (100g): shikonin 0.25g, lemongrass essential oil 0.35g, propylene glycol 3.0g, olive oil 5.0g, lanolin 12.0g, stearic acid 4.5g, cetyl wax 6.5g, cetyl alcohol 12.0g, Triethanolamine 0.2g, ethylparaben 0.1g, deionized water added to 100g.

[0025] Preparation method: Weigh the prescribed amount of shikonin and add it to propylene glycol, shake it at 30-40°C for 30 minutes, add olive oil, lanolin, stearic acid, cetyl wax, cetyl alcohol after fully dissolving, mix and melt to 80 ℃, to get the oil phase; another triethanolamine, ethylparaben and deionized water were heated and dissolved to 80 ℃ to get the water phase; the oil phase was slowly added to the water phase, stirring while adding; below 45 ℃, add lemongrass essential oil and stir Evenly, let it cool to get the cream.

Embodiment 3

[0026] Embodiment 3 A kind of composition and gel with antibacterial and anti-inflammatory effect

[0027] Formula ingredients (100 grams): 0.06g shikonin, 1.0g lemongrass essential oil, 8.5g glycerin, 2.5g carbomer, 0.05g triethanolamine, 0.4g polyvinylpyrrolidone, and the rest is deionized water.

[0028] Preparation method: Add shikonin and carbomer to glycerin and grind until wet, add distilled water and grind again; add polyvinylpyrrolidone, lemongrass essential oil, and triethanolamine to deionized water to dissolve them, and then put them in the first step mixture Stir in medium to make it into a gel, and the gel can be obtained after filling.

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PUM

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Abstract

The invention discloses a composition containing alkannin and lemon grass essential oil. The composition comprises an active ingredient which comprises alkannin and lemon grass essential oil. In the composition disclosed by the invention, the alkannin and the lemon grass essential oil are natural ingredients and have obvious effects of increasing efficiency, resisting bacteria and diminishing inflammation. The composition is used for treating diseases of dermatitis and eczema and various skin injuries, does not contain unknown and known toxic components undefined in medicine effect, and is definite in curative effect, controllable in quality and safe in use.

Description

technical field [0001] The invention belongs to the technical field of biomedicine and therapeutic cosmetics, in particular to a composition containing shikonin and lemongrass essential oil. Background technique [0002] Dermatitis and eczema diseases and various acute skin injuries are one of the most common clinical diseases, and they all need to be treated to inhibit the inflammatory response and prevent microbial infection. Western medicine antibacterial drugs are mostly antibacterial drugs and antifungal drug antibiotics. Western medicines for treating inflammatory and allergic skin diseases are mostly corticosteroids and antihistamines. Although these drugs have temporary effects, they often Deterioration occurs, which is the so-called "rebound phenomenon". Long-term application of the above drugs will cause many side effects. With the improvement of people's living standards, people pay more and more attention to drug safety and side effects while pursuing therapeuti...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P31/04A61P29/00A61P17/02A61P7/00A61P17/10A61P3/10A61P17/00A61K31/122
CPCA61K31/122A61K9/0014A61K9/06A61K9/12A61K9/7053A61K36/899A61K47/10A61K47/14A61K2300/00
Inventor 杨永安魏元刚钟慧金显友袁继文
Owner 南京紫源康医药科技有限公司
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