Medicine composition for treating esophagus cancer at middle and late stages

A composition and technology for esophageal cancer, which can be used in drug combinations, antitumor drugs, pharmaceutical formulations, etc., and can solve problems such as unsatisfactory curative effects

Inactive Publication Date: 2016-05-11
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has a certain therapeutic effect, but the curative effect is not satisfactory

Method used

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  • Medicine composition for treating esophagus cancer at middle and late stages

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1: Pharmaceutical composition for treating advanced esophageal cancer and its preparation method

[0034] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating middle-advanced esophageal cancer are: 480g of emodin methyl ether diglucoside 6690g of Zhejiang Lingzixiang 5600g of Echinacea;

[0035] Preparation:

[0036] (1) According to the ratio of raw materials, take emodin methyl ether diglucoside, Zhejiang Lingzixiang, and scutellaria, mix well, use ethanol with a concentration of 32% by weight as a solvent, and extract by warm soaking at 36.5°C, and the number of extractions is 19 time, each extraction time is 37 hours, and each solvent consumption is 27 times of the total weight of the bulk drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.13, filters, The drug solution passes through the XDA-6 macroporous adsorption resin colu...

Embodiment 2

[0039] Example 2: Medicinal composition for treating advanced esophageal cancer and its preparation method

[0040] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating middle-advanced esophageal cancer are: emodin methyl ether diglucoside 460g Zhejiang Lingzixiang 6700g scutellaria scutellaria 5500g;

[0041] Preparation:

[0042] (1) According to the ratio of raw materials, take emodin methyl ether diglucoside, Zhejiang Lingzixiang, and scutellaria, mix well, use ethanol with a concentration of 32% by weight as a solvent, and extract by warm soaking at 36.5°C, and the number of extractions is 19 time, each extraction time is 37 hours, and each solvent consumption is 27 times of the total weight of the bulk drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.13, filters, The drug solution passes through the XDA-6 macroporous adsorption resin colu...

Embodiment 3

[0045] Embodiment 3: The pharmaceutical composition and its preparation method for the treatment of advanced esophageal cancer

[0046] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating middle and advanced esophageal cancer are: 490g of emodin methyl ether diglucoside, 6680g of Zhejiang Lingzixiang, 5700g of D.

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take emodin methyl ether diglucoside, Zhejiang Lingzixiang, and scutellaria, mix well, use ethanol with a concentration of 32% by weight as a solvent, and extract by warm soaking at 36.5°C, and the number of extractions is 19 time, each extraction time is 37 hours, and each solvent consumption is 27 times of the total weight of the bulk drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.13, filters, The drug solution passes through the XDA-6 macroporous adsorption r...

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PUM

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Abstract

The invention discloses a medicine composition for treating esophagus cancer at middle and late stages and a preparation method of the medicine composition. The medicine composition is prepared from physcion diglucoside, all-grass of Chekiang Chelonopsis and thyrocarpus sampsonii, can be prepared into various dosage forms according to a conventional preparation process and has a remarkable treatment effect on treating esophagus cancer at middle and late stages.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating middle-advanced esophageal cancer and a preparation method thereof. Background technique [0002] Esophageal cancer belongs to the category of "choking diaphragm" disease in traditional Chinese medicine. "Lingshu. Evil Qi Viscera Disease Form" contains a description of "spleen pulse is slightly urgent, it is in the diaphragm, food and drink enter and then exit, and then fertilization ends", which is similar to the symptoms of this disease. In the Yuan Dynasty, Zhu Danxi said that "it is on the top, and it is close to the bottom of the throat...", and clearly pointed out the location of the lesion. Qing. Wu Jutong thought: "Generally, choking is due to half a hundred years of yang decline and yin knot." Yang deficiency is inevitable for aging, and yang deficiency and cold accumulation are important pathog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61P35/00A61K31/704
CPCA61K36/53A61K9/2013A61K9/2054A61K9/4858A61K31/704A61K36/30A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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