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Diabetic foot treating nano-level pharmaceutical composition and preparation method thereof

A kind of diabetic foot, nano-scale technology, applied in the direction of drug combination, medical raw materials derived from ferns/filamentous plants, drug delivery, etc., can solve the problems of easy recurrence, small side effects, limited curative effect, etc., and achieves low cost and medicinal properties. Gentle, curative effect

Inactive Publication Date: 2016-04-13
韩海霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most people's wounds can recover by themselves within one to two weeks, but diabetic foot patients, due to the lack of ability to repair wounds by themselves, and are prone to increase the chance of cell infection, may not recover for more than three months, and there may be spread of infection, and even severe infection And surgery to amputate the foot was necessary to save life
[0003] There have also been many applications in China, for example CN101085105A relates to a kind of external medicine for treating cervical spondylosis, femoral head necrosis and diabetic foot; CN101041086A relates to a kind of traditional Chinese medicine moist dressing for treating diabetic foot and its preparation method; However, the curative effect of these methods is limited after research. Although the price is low and the side effects are small, the effect is single, the course of treatment is long and it is easy to relapse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A nano-scale pharmaceutical composition for nursing diabetic foot. The raw materials and their parts by weight are: 30 parts of Yanjielian, 30 parts of Scutellaria chinensis, 30 parts of thorn bone wood, 32 parts of Kaempferia, 30 parts of Bailong Chuancai, 28 parts of bromeliad root, 25 parts of fenugreek root, 22 parts of Potentilla bilobata, 20 parts of catechu, 18 parts of Shenjincao, 16 parts of Piper longum, 15 parts of pod fern, 12 parts of Clematis, 10 parts of Desmodium grandiflora, 8 parts of Desmodium japonica, 6 parts of Chrysanthemum chinensis, 4 parts of celery extract, 26 parts of high-calcium vegetable extract; 0.8 parts of zinc oxide powder with a particle size of 50 nanometers and a particle size of 50 - 0.3 parts of titanium dioxide powder with a particle size of 100 nanometers, 0.2 parts of sodium hydroxide powder with a particle size of 50-100 nanometers, 0.2 parts of seaweed powder with a particle size of 50-100 nanometers, 0.2 parts of salicylic ac...

Embodiment 2

[0047] A nano-scale pharmaceutical composition for nursing diabetic foot, the raw materials and their parts by weight are: 40 parts of Yanjielian, 40 parts of Scutellaria chinensis, 40 parts of thornwood, 40 parts of Kaempferia, 37 parts of Bailongchuancai, 34 parts of bromeliad root, 30 parts of fenugreek root, 26 parts of Potentilla bifidae, 26 parts of catechu, 25 parts of Shenjincao, 23 parts of Piper longum, 21 parts of pod fern, 19 parts of Clematis, 16 parts of Desmodium grandiflorum, 14 parts of Desmodium chinensis, 10 parts of Trichosanthes chinensis, 7 parts of Trichosanthes extract, 32 parts of high-calcium vegetable extract; 0.6 parts of zinc oxide powder with a particle size of 50-100 nanometers, particle size 0.25 parts of titanium dioxide powder with a particle size of 50-100 nanometers, 0.25 parts of sodium hydroxide powder with a particle size of 50-100 nanometers, 0.25 parts of seaweed powder with a particle size of 50-100 nanometers, 0.25 parts of salicylic a...

Embodiment 3

[0069] A nano-scale pharmaceutical composition for nursing diabetic foot. The raw materials and their parts by weight are: 50 parts of Yanjielian, 50 parts of Scutellaria chinensis, 50 parts of thornwood, 48 parts of Kaempferia, 44 parts of Bailongchuancai, 40 parts of bromeliad root, 36 parts of fenugreek root, 34 parts of Potentilla bifidae, 33 parts of catechu, 32 parts of sinensis, 30 parts of Piper longum, 28 parts of fern root, 26 parts of clematis, 23 parts of Desmodium chinensis, 20 parts of Desmodium japonica, 14 parts of Cottonia chinensis, 10 parts of Phyllostachys chinensis extract, 38 parts of high-calcium vegetable extract; 0.8 parts of zinc oxide powder with a particle size of 50-100 nanometers, particle size 0.3 part of titanium dioxide powder with a particle size of 50-100 nm, 0.3 part of sodium hydroxide powder with a particle size of 50-100 nm, 0.3 part of seaweed powder with a particle size of 50-100 nm, 0.3 part of salicylic acid, and 0.3 part of vitamin E ...

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Abstract

The invention discloses a diabetic foot treating nano-level pharmaceutical composition and a preparation method thereof. The diabetic foot treating nano-level pharmaceutical composition is prepared from dichocarpum dalzielii, rhizoma dioscoreae tokoro, canthium horridum blume, rhizoma kaempferiae, panzeria alashanica, sageretia root, radix loropetalum chinense, potentilla bifurca, catechu, lycopodium clavatum, fructus piperis longi, rhizoma matteucciae struthiopteris, radix clematidis, herba lysimachiae, sedum amplibracteatum, stellaria media, purple lythrum extract, sedum aizoon extract, zinc oxide powder with particle size ranging from 50 nanometers to 100 nanometers, titanium dioxide powder with particle size ranging from 50 nanometers to 100 nanometers, sodium hydroxide powder with particle size ranging from 50 nanometers to 100 nanometers, seawood meal powder with particle size ranging from 50 nanometers to 100 nanometers, salicylic acid, vitamin E and vitamin C. Based on the traditional Chinese medicine theory that treating internal illness by external treatment according to both symptoms and root causes, the pharmaceutical composition has functions of diminishing inflammation, detoxifying, clearing stasis and promoting granulation to symptoms of diabetic feet, further prompts complete healing of gangrenous wounds while keeping regenerated skin smooth and flat without obvious scars, and is mild in property without any side and toxic effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a nanoscale pharmaceutical composition for nursing diabetic feet and a preparation method thereof. Background technique [0002] Diabetic foot is a common complication of diabetes, and it is one of the epidemics with high incidence and serious harm in my country. It is understood that the mortality rate of diabetes complications is second only to cardiovascular disease, cerebrovascular disease and tumors, ranking fourth. The number of diabetic patients in China is close to 40 million, ranking third in the world, an increase of 5 times compared with 0.7% in the 1980s. Diabetic foot is one of the serious complications of diabetes, with an incidence rate of 15% to 20%, and it is the main cause of amputation and disability. Diabetic foot is most common in middle-aged and elderly people with a long history of diabetes and poor long-term blood sugar control. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61P3/10A61P17/02A61K31/198A61K31/375A61K31/4415A61K31/05
CPCA61K36/71A61K9/0014A61K9/06A61K9/12A61K31/05A61K31/198A61K31/375A61K31/4415A61K36/11A61K36/185A61K36/36A61K36/41A61K36/48A61K36/53A61K36/67A61K36/716A61K36/72A61K36/73A61K36/74A61K36/896A61K36/90A61K36/906A61K47/46A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 韩海霞孙晓伟
Owner 韩海霞
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