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Medicine composition for treating hyperplasia of mammary glands and preparation method thereof

A technology of mammary gland hyperplasia and composition is applied in the field of pharmaceutical composition, pharmaceutical composition for treating mammary gland hyperplasia and preparation field thereof, which can solve the problems of long treatment time, slow onset of effect, disorder of hormone metabolism, etc. The effect of milk ducts

Inactive Publication Date: 2016-04-06
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, surgery or hormone and receptor blockers are often used for this disease. Although the curative effect is effective, it often leads to disordered hormone metabolism after the disease is cured.
However, some oral medicines are not effective enough, the treatment time is long, and the onset of effect is slow.

Method used

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  • Medicine composition for treating hyperplasia of mammary glands and preparation method thereof
  • Medicine composition for treating hyperplasia of mammary glands and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A pharmaceutical composition for treating mammary gland hyperplasia, prepared by the following method:

[0036] (1) Raw material pretreatment: Remove impurities and mildewed parts from the raw materials of Chinese medicine, iron leaf, flat wood, star anise lotus, August leaf, panax notoginseng, heather vine, perilla, and scorpion, wash, dry, and crush and grow separately Fragments with a thickness of 3 to 5 cm;

[0037] (2) Decocting and filtering: After pretreatment in step (1), the iron leaf, flat wood, star anise lotus, August Zha, Panax notoginseng, heather vine, perilla, and scorpion are in a weight ratio of 4:3:3 : 1:1:4:1:0.3 ratio and mix evenly, then add 60 times the weight of pure water, decoct 5 times, each 20min; carry out coarse filtration to above-mentioned each decocting liquid respectively, filter step by step (using 100 mesh, 200 mesh, 300 mesh and 400 mesh sieves successively) to remove floating debris and retain the filtrate to obtain the crude filtr...

Embodiment 2

[0042] A pharmaceutical composition for treating mammary gland hyperplasia, prepared by the following method:

[0043] (1) Raw material pretreatment: Remove impurities and mildewed parts from the raw materials of Chinese medicine, iron leaf, flat wood, star anise lotus, August leaf, panax notoginseng, heather vine, perilla, and scorpion, wash, dry, and crush and grow separately Fragments with a thickness of 3 to 5 cm;

[0044] (2) Decocting and filtering: After pretreatment in step (1), the iron leaf, flat wood, star anise lotus, August Zha, Panax notoginseng, heather vine, perilla, and scorpion are in a weight ratio of 4:3:3 : 1:1:4:1:0.3 ratio and mix evenly, then add 60 times the weight of pure water, decoct 5 times, each 20min; carry out coarse filtration to above-mentioned each decocting liquid respectively, filter step by step (using 100 mesh, 200 mesh, 300 mesh and 400 mesh sieves successively) to remove floating debris and retain the filtrate to obtain the crude filtr...

Embodiment 3

[0049] A pharmaceutical composition for treating mammary gland hyperplasia, prepared by the following method:

[0050] (1) Raw material pretreatment: Remove impurities and mildewed parts from the raw materials of Chinese medicine, iron leaf, flat wood, star anise lotus, August leaf, panax notoginseng, heather vine, perilla, and scorpion, wash, dry, and crush and grow separately Fragments with a thickness of 3 to 5 cm;

[0051] (2) Decocting and filtering: After pretreatment in step (1), the iron leaf, flat wood, star anise lotus, August Zha, Panax notoginseng, heather vine, perilla, and scorpion are 4:5:5 according to the weight ratio : 3: 1: 3: 2: 0.1, mix evenly, then add 60 times the weight of pure water, decoct 5 times, each time for 20 minutes; carry out coarse filtration to the above-mentioned decoction liquids, and filter step by step (using 100 mesh, 200 mesh, 300 mesh and 400 mesh sieves successively) to remove floating debris and retain the filtrate to obtain the cr...

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Abstract

The invention discloses a medicine composition for treating the hyperplasia of mammary glands and a preparation method thereof. The medicine composition is prepared from 20-30 parts of traditional Chinese medicine preparation, 5-10 parts of folium ginkgo extract, 1-5 parts of chondroitin sulfate, 0.1-0.3 parts of pterostilbene and 0.1-1 part of diosmetin. The traditional Chinese medicine preparation is prepared from folium cycas, Japanese ardisia, dysosma versipellis, fiveleaf akebia fruit, pseudo-ginseng, piper wallichii, purple perilla and scorpions according to the weight ratio of (3-5):(2-6):(2-5):(1-3):(1-3):(3-5):(1-2):(0.1-0.5) through decocting, filtering and concentrating. The medicine composition has functions of promoting blood circulation to remove blood stasis, stimulating menstrual flow to remove stasis, dredging channels by soothing liver, dredging latex vessels, promoting qi circulation to relieve pain, expelling wind and relieving muscular spasm, clearing away heat to remove blood stasis and the like, and has an excellent effect on treating the hyperplasia of mammary glands.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating mammary gland hyperplasia and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] Mammary gland hyperplasia refers to hyperplasia of mammary gland epithelium and fibrous tissue, structural degeneration of breast tissue ducts and lobules, and progressive connective tissue growth. It is the most common breast disease in women. The main causes of mammary gland hyperplasia are the absolute or relative increase of estrogen, as well as adverse mental factors such as excessive mental stress or emotional excitement. Mammary gland hyperplasia is a common and frequently-occurring disease in women of childbearing age, accounting for about 75% of breast diseases, and 2%-5% of patients develop cancer. Hyperplasia of mammary glands belongs to the category of "breast addiction" in t...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/48A61P15/14A61K31/09A61K31/352A61K31/737A61K35/646
CPCA61K36/88A61K9/4808A61K31/09A61K31/352A61K31/737A61K35/646A61K36/16A61K36/185A61K36/258A61K36/29A61K36/535A61K36/67A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 赵振寰荆伟丽李冬梅朱莉曲海军
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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