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Oral traditional Chinese medicine preparation for treating and preventing ocular disorders of diabetic complication

A technology for traditional Chinese medicine preparations and complications, which is applied in the directions of medical preparations containing active ingredients, metabolic diseases, sensory diseases, etc., to achieve the effects of simple process, obvious curative effect, and life protection.

Inactive Publication Date: 2016-01-27
TANGBEINING MEDICINE SCI & TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But diabetes is not terrible, what is terrible is the complications of diabetes, and currently there is no drug in the world medical field that can cure diabetes or effectively prevent people with diabetes from developing complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0010] This specific embodiment is composed of 600-999 parts of Angelica, 600-999 parts of Anemarrhena, 400-999 parts of Achyranthes bidentata, 400-999 parts of Rhizoma Chuanxiong, 200-999 parts of Kelp, 200-999 parts of C. 200-999 parts of Rehmannia glutinosa, 100-999 parts of Scrophulariae Radix Scrophulariae, 100-999 parts of Saffron Flower, and 100-999 parts of Licorice.

[0011] Take 1 / 3 of 600-999 parts of angelica and grind them into fine powder, and set aside; add 8 times the amount of water to decoct the rest of angelica and Anemarrhena for 2 times, each time for 1 hour; filter, combine the decoction, and concentrate under reduced pressure to Clear paste with a relative density of 1.10-1.14 (50°C); add ethanol to make the alcohol content reach 70%, leave it for 24 hours, and filter; recover ethanol from the supernatant under reduced pressure, concentrate to a relative density of 1.25-1.30 (50°C) -70°C) thick paste; vacuum drying (below 70°C); dry paste crushed into fi...

specific Embodiment approach 2

[0012] According to the pharmaceutical method, the preparation of the present invention can be prepared into various clinical dosage forms, including oral liquid, tablet, capsule, drop pill, granule, suspension, transdermal preparation, injection, suppository, aerosol any of these agents, etc.

specific Embodiment approach 3

[0013] Specific embodiment three: the patent of the present invention is realized through the following preclinical research.

[0014] 1. According to the results of pharmacodynamic experiments, the patent of the present invention has the following functions:

[0015] 1. It has a strong effect on improving eye lesions in rats with experimental diabetic complications.

[0016] 2. It has different degrees of blood sugar lowering effects on rats with diabetic complications and eye lesions, especially in the high-dose group.

[0017] 3. It has inhibitory effect on Staphylococcus aureus, Staphylococcus epidermidis and Proteus in rats with diabetic complications and eye lesions, and the inhibition rates are 94%, 87% and 76% respectively.

[0018] 4. It has a protective effect on Staphylococcus aureus infection in mice with diabetic complications and eye lesions.

[0019] 5. It has a protective effect on the infection of Pseudomonas aeruginosa in mice with diabetic complications an...

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Abstract

An oral traditional Chinese medicine preparation for treating and preventing ocular disorders of diabetic complication is disclosed. The invention relates to a traditional Chinese medicine preparation, specifically to a traditional Chinese medicine preparation for treating and preventing ocular disorders of diabetic complication. The oral traditional Chinese medicine preparation of the invention is composed of 600-999 parts of Chinese angelica, 600-999 parts of anemarrhena, 400-999 parts of achymthes bidentata blume, 400-999 parts of ligusticum wallichii, 200-999 parts of Ecklonia kurome, 200-999 parts of motherwort fruit, 200-999 parts of chrysanthemum, 200-999 parts of radix rehmanniae, 100-999 parts of radix scrophulariae, 100-999 parts of fructus polygoni orientalis and 100-999 parts of licorice. The oral traditional Chinese medicine preparation has characteristics of remarkable curative effect, simple technology and low cost, can be used in effectively treating and preventing ocular disorders of diabetic complication, remarkably raising immunity of patients with diabetes and ocular disorders of diabetic complication and effectively protecting life of patients.

Description

technical field [0001] The patent of the present invention relates to traditional Chinese medicine preparations, and specifically relates to the treatment and prevention of eye lesions with diabetic complications, which can significantly improve the immunity of patients with diabetes and eye lesions with diabetic complications, and effectively protect the lives of patients with diabetes and eye lesions with diabetic complications. Oral Chinese medicine preparations. Background technique [0002] At present, there are more than 300 million diabetic patients who have been diagnosed and treated in the world (the actual diabetic patients have reached nearly 500 million). The latest survey shows that China has surpassed India to become the world's largest diabetes country. The number of patients diagnosed with diabetes in my country has reached as high as 90 million, and the number of people with glucose tolerance is as high as 148 million. That is to say, one out of every 5-6 ...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P3/10A61P27/02
Inventor 刘建勋仝燕张瑞祥李宪昌李冠祥张传吉
Owner TANGBEINING MEDICINE SCI & TECH BEIJING
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