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Application of a kind of Xanthomonas longitudinal stripes

A technology of vertical stripes and carbon horn bacteria, which is applied to medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulations, etc., can solve problems such as information that has not yet been applied in the field of sedation and hypnosis, and achieve prevention And treatment of insomnia diseases, good medicinal prospects, strong pharmacological effects

Active Publication Date: 2019-07-16
SOUTHWEAT UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, there have been literatures reporting the cultivation method of Pyramidus verticalis, but there is no information on the application of this bacterium in the field of sedation and hypnosis.

Method used

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  • Application of a kind of Xanthomonas longitudinal stripes
  • Application of a kind of Xanthomonas longitudinal stripes
  • Application of a kind of Xanthomonas longitudinal stripes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Studies on the toxicology and sedative-hypnotic activity of the fruiting body of Xanthomonas vertical stripes:

[0036] 1. Materials and equipment

[0037] 1.1 Main materials and reagents

[0038] The fruiting body powder of Xanthomonas vertical stripes was provided by the Microbiology Laboratory of Southwest University of Science and Technology, Sichuan Province. The dried fruiting bodies were crushed through a 100-mesh sieve, and distilled water was used to make an aqueous solution of fruiting body bacteria powder for oral administration.

[0039] Sodium pentobarbital: Sichuan Chemical Reagent Company (imported and repackaged from Germany), batch number: 130919.

[0040] 1.2 Experimental animals

[0041] Kunming white mice, normal grade, weighing 20-22 g, half male and half male, strain: SPFKM, animal certificate number: SCXK (Sichuan) 2008-0005, provided by Sichuan Jianyang Shuoda Animal Technology Co., Ltd. Breeding conditions: The animal room is of ordinary gra...

Embodiment 2

[0070] Study on the sedative and hypnotic effects of the alcohol extract of C.

[0071] 1. Test material

[0072] 1.1 Main materials and reagents

[0073] Alcohol extract of Carbonara vertical stripes: take the fruiting body of Carbonara vertical stripes, crush and sieve, extract the powder with 10 times the amount of 95% (W / W) ethanol under reflux for 3 times, and filter each extract through a G4 sand core funnel , and the combined filtrates were concentrated under reduced pressure until there was no alcohol smell, and then vacuum-dried to obtain the alcohol extract of C. longitudinal stripes.

[0074] Alcohol extract, medicinal dregs, Xanthomonas vertical stripes powder, Ganoderma lucidum powder, and estazolam are all made into a certain concentration suspension with distilled water.

[0075] Sodium pentobarbital: Sichuan Chemical Reagent Company (imported and repackaged from Germany), batch number: 130919.

[0076] 1.2 Experimental animals

[0077] Kunming white mice, n...

Embodiment 3

[0095] Preparation of health granules:

[0096] Take 10 grams of the extracted carbonaceous alcohol extract, mix it with 790 grams of fruit juice powder and 200 grams of powdered sugar, pass through a 12-mesh sieve, dry at 75°C, and pack it into a bag, which has a sedative and hypnotic effect. The granules, each bag contains 100mg of vertical striped carbonic acid extract. For the treatment of neurological diseases such as insomnia and anxiety.

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Abstract

The invention discloses application of longitudinal stripe xylaria. The application is characterized in that sporocarp or alcohol extract of the longitudinal stripe xylaria can be applied to preparing a composition with a sedative effect, a composition with a hypnotic effect and a composition used for treating insomnia or anxiety; the compositions are medicine compositions or food compositions or health-care product compositions. The sporocarp of the longitudinal stripe xylaria is obtained through artificial culture, and the alcohol extract of the longitudinal stripe xylaria is obtained through extraction and concentration. The sporocarp or the alcohol extract of the longitudinal stripe xylaria has the remarkable sedative-hypnotic effect, is a natural active material for researching and developing novel health-care food and new medicine with the sedative-hypnotic effect, can be used for treating nervous system diseases such as insomnia or anxiety or convulsions, and is good in effect.

Description

technical field [0001] The invention belongs to the application of a higher fungus and its alcohol extract (or called alcohol extract), and relates to the application of a type of Xanthomonas longitudinal stripes. The fruiting body powder and alcohol extract of the higher fungus Xylocarpus longitudinal stripes provided by the invention are particularly suitable for improving human sleep and the like. Background technique [0002] Insomnia is a clinical frequently-occurring disease of human beings with complex etiology and easy recurrence. The findings of the World Health Organization show that about 33% of people have sleep disorders every year. In traditional treatment, Western medicine sedative and hypnotics are usually given. These drugs generally have large side effects and strong dependence. In recent years, in the face of the global sedative-hypnotic drug market of more than 10 billion US dollars, natural sedative-hypnotic drugs based on traditional Chinese medicine ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/062A61P25/20A61P25/22A23L31/00A23L33/10A23F3/14
Inventor 黄毅雷传文袁小红贺新生侯大斌周芸曾晏萍
Owner SOUTHWEAT UNIV OF SCI & TECH
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