Itching-relieving anti-inflammatory compound preparation and preparation method thereof

A compound preparation and solution technology, applied in the directions of anti-inflammatory agents, non-central analgesics, drug combinations, etc., can solve the problems of cracks and lichenification changes, patients suffering from pain, skin diseases itching, etc. Toxic side effects, simple ingredients

Inactive Publication Date: 2016-01-20
杨志宇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Skin diseases are common diseases that frequently occur in people. Some skin diseases have complex causes, which bring inconvenience and pain to people's life, work and spirit due to prolonged unhealed, such as contact dermatitis, papular urticaria, subacute Eczema, neurodermatitis and psoriasis, etc., severe skin keratosis, thickening, roughness, desquamation, cracks and lichenification changes. In most parts of southern my country, due to the hot and humid climate, people are prone to various diseases. Pruritus skin diseases, especially in rural areas, are prone to various skin diseases and cross-infection due to outdoor work and poor living and hygienic conditions for farmers. Some skin diseases are extremely itchy and difficult for patients. Endurance and scratching lead to a more serious condition, and the patient suffers unbearably, which seriously affects work, study and rest. Most of the existing oral medicines and topical medicines for skin diseases cannot be rooted out and relapse, which makes the patients troubled

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The antipruritic and anti-inflammatory compound preparation comprises dexamethasone acetate, menthol, aluminum acetate, ethanol, dimethyl sulfoxide and purified water, and the parts by weight of each component are: 0.25 parts of dexamethasone acetate, 20 parts of menthol, 70 parts of 10% aluminum acetate solution, 500 parts of ethanol, 3 parts of dimethyl sulfoxide, and 300 parts of purified water.

[0016] The preparation method of this antipruritic and anti-inflammatory compound preparation comprises the following steps:

[0017] (1) Mix the dexamethasone acetate and dimethyl sulfoxide and stir evenly;

[0018] (2) Mix the menthol and ethanol and stir evenly;

[0019] (3) Add the purified water into the solution prepared in step (2), and stir evenly;

[0020] (4) Slowly add the solution prepared in step (1) to the solution prepared in step (3) successively;

[0021] (5) Slowly add the 10% aluminum acetate solution into the solution prepared in step (4) successively...

Embodiment 2

[0024] The antipruritic and anti-inflammatory compound preparation comprises dexamethasone acetate, menthol, aluminum acetate, ethanol, dimethyl sulfoxide and purified water, and the parts by weight of each component are: 0.15 parts of dexamethasone acetate, 18 parts of menthol, 50 parts of 10% aluminum acetate solution, 450 parts of ethanol, 2 parts of dimethyl sulfoxide, and 250 parts of purified water.

[0025] The preparation method of this antipruritic and anti-inflammatory compound preparation comprises the following steps:

[0026] (1) Mix the dexamethasone acetate and dimethyl sulfoxide and stir evenly;

[0027] (2) Mix the menthol and ethanol and stir evenly;

[0028] (3) Add the purified water into the solution prepared in step (2), and stir evenly;

[0029] (4) Slowly add the solution prepared in step (1) to the solution prepared in step (3) successively;

[0030] (5) Slowly add the 10% aluminum acetate solution into the solution prepared in step (4) successively...

Embodiment 3

[0033] The antipruritic and anti-inflammatory compound preparation comprises dexamethasone acetate, menthol, aluminum acetate, ethanol, dimethyl sulfoxide and purified water, and the parts by weight of each component are: 0.35 parts of dexamethasone acetate, 22 parts of menthol, 90 parts of 10% aluminum acetate solution, 550 parts of ethanol, 4 parts of dimethyl sulfoxide, and 350 parts of purified water.

[0034] The preparation method of this antipruritic and anti-inflammatory compound preparation comprises the following steps:

[0035] (1) Mix the dexamethasone acetate and dimethyl sulfoxide and stir evenly;

[0036] (2) Mix the menthol and ethanol and stir evenly;

[0037] (3) Add the purified water into the solution prepared in step (2), and stir evenly;

[0038] (4) Slowly add the solution prepared in step (1) to the solution prepared in step (3) successively;

[0039] (5) Slowly add the 10% aluminum acetate solution into the solution prepared in step (4) successively...

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PUM

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Abstract

The invention discloses an itching-relieving anti-inflammatory compound preparation and a preparation method thereof and belongs to the technical field of skin treatment drugs. The itching-relieving anti-inflammatory compound preparation is prepared from, by weight, 0.15-0.35 part of dexamethasone acetate, 18-22 parts of menthol, 50-90 parts of 10% aluminum acetate solution, 450-550 parts of ethanol, 2-4 parts of dimethyl sulfoxide and 250-350 parts of purified water. The invention further provides a preparation method of the itching-relieving anti-inflammatory compound preparation. The itching-relieving anti-inflammatory compound preparation contains simple components, is convenient to prepare, has better itching-relieving, desensitizing and anti-inflammatory effects, has no obvious toxic and side effects and meets the demand for skin treatment.

Description

technical field [0001] The invention belongs to the technical field of skin treatment medicines, and specifically relates to an antipruritic and anti-inflammatory compound preparation and a preparation method thereof. Background technique [0002] Skin diseases are common diseases that frequently occur in people. Some skin diseases have complex causes, which bring inconvenience and pain to people's life, work and spirit due to prolonged unhealed, such as contact dermatitis, papular urticaria, subacute Eczema, neurodermatitis and psoriasis, etc., severe skin keratosis, thickening, roughness, desquamation, cracks and lichenification changes. In most parts of southern my country, due to the hot and humid climate, people are prone to various diseases. Pruritus skin diseases, especially in rural areas, are prone to various skin diseases and cross-infection due to outdoor work and poor living and hygienic conditions for farmers. Some skin diseases are extremely itchy and difficult f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/573A61P17/04A61P17/06A61P29/00A61P37/08A61K31/045A61K31/19
Inventor 杨志宇
Owner 杨志宇
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