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Traditional Chinese medicinal liquid band aid for preventing and treating bedsore complicated with bacterial infection

A liquid band-aid, bacterial infection technology, applied in the direction of antibacterial drugs, drug combinations, pharmaceutical formulations, etc., can solve the problems of long course of disease, mechanical damage, unfavorable granulation tissue growth and wound healing, etc.

Inactive Publication Date: 2015-12-23
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, conventional disinfection, single antibiotic or other fungicide coating is mostly used. Because these drugs have strong stimulation on the wound surface, they are not conducive to the growth of granulation tissue and wound healing, and the course of disease is long. Emerging drug resistance and even now superbugs
When these drugs are used at the same time, if the gauze is not covered, it is easy to cause abrasions on the skin and the bed, and if the gauze is covered, it is easy to cause the dressing to adhere to the wound, and it is easy to cause mechanical damage when changing the dressing, increase the pain of the patient, and even expand the wound.

Method used

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  • Traditional Chinese medicinal liquid band aid for preventing and treating bedsore complicated with bacterial infection
  • Traditional Chinese medicinal liquid band aid for preventing and treating bedsore complicated with bacterial infection
  • Traditional Chinese medicinal liquid band aid for preventing and treating bedsore complicated with bacterial infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] prescription:

[0077] Medicinal materials: 20 parts of Senecio, 18 parts of bright-leaved holly, 3.5 parts of calamine, 10 parts of red peony, 6 parts of cocklebur, 13 parts of red vine, 12 parts of red, 15 parts of Hanxin grass, 9 parts of dried hemp share;

[0078] Excipients: 33 parts of polyvinyl acetal, 7 parts of dibutyl phthalate, 4.5 parts of methyl cellulose, 12 parts of glycerin, 12 parts of laurocapram, 170 parts of ethanol, 45 parts of ethyl acetate.

[0079] Preparation method: extract the pulverized Senecio, Radix Ilex, Xanthium, Hanxincao, Dianganma and 95% ethanol twice, each time for 1.5-2.0 hours, collect the ethanol extract filter residue, combine the extracts, Concentrate under reduced pressure at 55°C until the ethanol content is 4.5%, to obtain the ethanol extract concentrate; extract the red peony root, red flat rattan, a little red together with Senecio, bright leaf holly, cocklebur, Hanxin grass, and dried hemp with ethanol Add water to decoc...

Embodiment 2

[0081] prescription:

[0082]Medicinal materials: 23 parts of Senecio, 20 parts of bright-leaved holly, 4.0 parts of calamine, 10 parts of red peony, 5 parts of cocklebur, 15 parts of red vine, 14 parts of red, 15 parts of Hanxin grass, 10 parts of dried hemp share;

[0083] Excipients: 35 parts of polyvinyl acetal, 8 parts of dibutyl phthalate, 4.5 parts of methyl cellulose, 10 parts of glycerin, 10 parts of laurocapram, 180 parts of ethanol, 45 parts of ethyl acetate.

[0084] Preparation method: extract the pulverized Senecio, Radix Ilex, Xanthium, Hanxincao, Dianganma and 95% ethanol twice, each time for 1.5-2.0 hours, collect the ethanol extract filter residue, combine the extracts, Concentrate under reduced pressure at 50°C until the ethanol content is 4.0%, to obtain the ethanol extract concentrate; extract the red peony root, red flat rattan, a little red together with Senecio, bright-leaved holly, cocklebur, Hanxin grass, and dried hemp with ethanol Add water to dec...

Embodiment 3

[0086] prescription:

[0087] Medicinal materials: 30 parts of Senecio, 15 parts of bright-leaved holly, 5 parts of calamine, 12 parts of red peony, 8 parts of cocklebur, 15 parts of red vine, 15 parts of red, 13 parts of Hanxin grass, 12 parts of dried hemp share;

[0088] Excipients: 40 parts of polyvinyl acetal, 7 parts of dibutyl phthalate, 4.5 parts of methyl cellulose, 12 parts of glycerin, 12 parts of laurocapram, 180 parts of ethanol, 45 parts of ethyl acetate.

[0089] Preparation method: extract the pulverized Senecio, Radix Ilex, Xanthium, Hanxincao, Dianganma and 95% ethanol twice, each time for 1.5-2.0 hours, collect the ethanol extract filter residue, combine the extracts, Concentrate under reduced pressure at 60°C until the ethanol content is 4.5%, to obtain a concentrated ethanol extract; extract red peony root, red flat rattan, a little red together with Senecio, bright-leaved holly, cocklebur, Hanxin grass, and dried hemp with ethanol Add water to decoct th...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicinal liquid band aid for preventing and treating bedsore complicated with bacterial infection. The band aid is prepared from climbing groundsel herb, green holly, calamine, radix paeoniae rubra, cocklebur fruit, vitischungii metcalf, emilia sonchifolia, scutellaria indica and angled bittersweet root which serve as active ingredients according to certain parts by weight, as well as polyvinyl acetal, dibutyl phthalate, methyl cellulose, glycerol, laurocapram, ethanol and ethyl acetate. The band aid has functions of clearing away heat and toxic materials, diminishing inflammation and relieving swelling, promoting blood circulation and removing stasis, removing necrotic tissues and promoting generation of new tissues; the band aid is capable of effectively controlling growth and propagation of infectious pathogenic bacteria, and is simultaneously capable of improving microcirculation around a wound surface, enhancing local blood flow, promoting growth of granulation tissue and accelerating healing. The band aid is convenient to use and is not limited by the shape, size and location of wound; and meanwhile, the band aid is good in water-proofing and air-permeable properties, non-sticky to clothes, and free from allergy and drug tolerance.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine liquid wound dressing for preventing and treating bedsores complicated with bacterial infection. Background technique [0002] Pressure sores are tissue damage and necrosis caused by the loss of normal function of the skin due to long-term pressure on local tissues of the body, impaired blood circulation, and lack of tissue nutrition. Pressure sores themselves are not primary diseases, and most of them are skin damage caused by other primary diseases without good care. The most basic and important factors causing pressure sores are local tissue ischemia, hypoxia and necrosis caused by compression. [0003] In recent years, the incidence of decubitus sores is on the rise, and there are certain difficulties in the treatment of decubitus sores. Among patients with decubitus ulcers, most of them are senile diseases such as cere...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K9/70A61P31/04A61P17/02A61K33/30
Inventor 孙言芳
Owner 陈红
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