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Extraction method and application of plant composition containing herba epimedii

An extraction method and epimedium technology are applied in the directions of drug combinations, medical preparations containing active ingredients, plant raw materials, etc., which can solve the problems of large patient dosage, rough process, and many impurities, and achieve the effect of reducing the dosage.

Inactive Publication Date: 2015-12-02
NANJING ZHENGLIANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Epimedium. However, the method of decocting in water is rough and backward, and there are many impurities, which leads to excessive dosage for patients and is inconvenient to take. , seriously affecting the clinical application of this product

Method used

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  • Extraction method and application of plant composition containing herba epimedii

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 100 parts of Epimedium, 40 parts of Corsica chinensis, 60 parts of iron chopsticks, and 50 parts of Dawu bubble root, crush, add 2L of 70% ethanol, put it into a microwave extraction device for microwave extraction, and the extraction power is 400-600W, Extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluent, recover ethanol under reduced pressure, concentrate and After drying, microwave extracts were obtained, and conventional auxiliary materials were added to prepare tablets, 0.4 g per tablet.

Embodiment 2

[0016] Take 100 parts of Epimedium, 40 parts of Corsica chinensis, 60 parts of iron chopsticks, and 50 parts of Dawu bubble root, crush, add 2L of 70% ethanol, put it into a microwave extraction device for microwave extraction, and the extraction power is 400-600W, Extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluent, recover ethanol under reduced pressure, concentrate and After drying, microwave extracts are obtained, and conventional auxiliary materials are added to prepare capsules.

Embodiment 3

[0018] Take 100 parts of Epimedium, 40 parts of Corsica chinensis, 60 parts of iron chopsticks, and 50 parts of Dawu bubble root, crush, add 2L of 70% ethanol, put it into a microwave extraction device for microwave extraction, and the extraction power is 400-600W, Extract twice, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluent, recover ethanol under reduced pressure, concentrate and After drying, microwave extracts are obtained, and conventional auxiliary materials are added to prepare granules.

[0019] Galium verum L.var.asiaticumNakai is a Rubiaceae Corala vine, and the whole herb and root are used as medicine. Whole grass is collected in summer and autumn, and roots are dug in autumn. Wash and chop, use fresh or sun-dried. Clearing away heat and detoxifying, promoting blood circulation, relieving itching, and dampening; treating hepatitis, throat mo...

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Abstract

The invention provides an extraction method of a plant composition containing herba epimedii. The plant composition is prepared from 100 parts of herba epimedii, 40 parts of galium verum, 60 parts of helleborus thibetanus and 50 parts of rubus pluribracteatus roots by adopting the microwave extraction method, therefore, the content is greatly increased, and the using amount is decreased. The invention further provides an application of the plant composition containing the herba epimedii in preparation of medicine for inhibiting proliferation of melanic rattus lung fibroblast NRL2.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing Epimedium. Background technique [0002] The plant composition containing epimedium is made from 100 parts of epimedium, 40 parts of sagebrush, 60 parts of iron chopsticks, and 50 parts of Dawubaogen as raw materials. For 2-3 hours, the decoction was combined, filtered, concentrated into a thick paste, granulated, dried, and coated with sugar to obtain it. [0003] In the prior art, there is no report that the plant composition containing Epimedium adopts microwave technology in the aspect of extraction and preparation, but the method of decoction is rough, backward, and has many impurities, which causes the patient to consume too much and is inconvenient to take. , seriously affecting the clinical application of this product. SUMMARY OF THE INVENTION [0004] Purpose of t...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P35/00
Inventor 赵明亮
Owner NANJING ZHENGLIANG MEDICAL TECH
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