Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A compound in-body gel preparation of effective parts of traditional Chinese medicine for pain relief and preparation method thereof

A technology of effective parts and body gel, which is applied in the field of body gel preparations and preparations of compound effective parts of traditional Chinese medicine, which can solve the problems of difficult production, inconvenient use, loss of drug efficacy, etc., and achieves easy and accurate control of dosage and convenient use Effect

Active Publication Date: 2019-09-03
FOSHAN SOIN PHARMA CO LTD
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Liquid preparations are easy to flow, which will lose drug efficacy or contaminate clothes, which will bring inconvenience to use; semi-solid ointment, gel, cream, etc. are ideal forms, but they are difficult to make and the drug loading is limited. Compared with liquid preparations, the absorption is also slower; the solid form of the patch has a more complicated production process, generally going through high temperature, organic solvent dissolution, etc., and the absorption is the slowest

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A compound in-body gel preparation of effective parts of traditional Chinese medicine for pain relief and preparation method thereof
  • A compound in-body gel preparation of effective parts of traditional Chinese medicine for pain relief and preparation method thereof
  • A compound in-body gel preparation of effective parts of traditional Chinese medicine for pain relief and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A compound in-body gel preparation of effective parts of traditional Chinese medicines for pain relief, the composition of which is calculated by weight percentage and includes:

[0035]

[0036] Wherein, the total crocin glycosides described in the present invention are saffron extracts, and the crocin used is calculated as crocin-I, and its mass content is not less than 50%, preferably not less than 60%, more Preferably not less than 70%. Saffron is the stigma of the Iridaceae plant Saffron. It has the effects of promoting blood circulation and removing stasis, dispelling stagnation and knotting, cooling blood and detoxification. It contains crocin, saffron acid, ursolic acid, oleanolic acid, and saffron bitter , saffron aldehyde and other ingredients, of which crocin is the main active ingredient.

[0037] There are two main sources of paeonol in plants, i.e. Cortex Moutan and Xu Changqing. The source of paeonol in the present invention is the paeonol extracted f...

Embodiment 2 to Embodiment 7

[0048] In Example 2 to Example 7, a compound in-body gel preparation of effective parts of traditional Chinese medicines for pain relief provided by the present invention is calculated by weight percentage, and its composition content is shown in the following table:

[0049]

[0050]

[0051] In addition, in embodiment 1 to embodiment 7, the kind of auxiliary agent used is shown in the following table:

[0052]

[0053] The preparation method steps of embodiment 2 to embodiment 7 are the same as embodiment 1.

[0054] The present invention proposes a compound prescription of effective parts of traditional Chinese medicine for pain relief, which is liquid in body gel preparation at normal temperature, and can be in the form of solution, liniment, etc., or can be directly adsorbed on absorbent materials such as needle-punched cloth. Made in patch form (similar to wet wipes). In the form of solution or liniment, it can be directly applied to the affected area, and then...

example 2

[0065] Typical case 2: Zhang Moumou, male, 26 years old, who lives in Bodun City, Chancheng District, Foshan City, accidentally sprained his knee and developed pain and swelling. With the local application of the product of this embodiment 2, once a day, the pain obviously took a turn for the better the next day, and the pain disappeared and the swelling disappeared after five weeks. Patients said: the product is particularly effective and easy to use.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
Login to View More

Abstract

The invention provides a compound in-situ gel preparation with Chinese medicine active part used for pain relieving and a preparation method thereof. The compound in-situ gel preparation comprises the following components by weight percentage: 0.03-1.0% of saffron total glycoside, 0.05-3.0% of paeonol, 0.05-2.0% of total saponins of clematis, 0.05-2.0% of total paeony glycoside, 10-22% of poloxamer 407, 3-18% of poloxamer 188, 17-38% of auxiliary agent and the balance of purified water. According to the invention, the compound in-situ gel preparation with Chinese medicine active part is liquid under normal temperature, and becomes gel due to influence of body temperature and is adhered on the skin, drug efficacy loss due to soup flowing can be effectively avoided, dosage is easily and accurately controlled, concentration of effective medicine can be kept, treatment effect is enhanced, and absorption is faster. The invention also provides a preparation method of the compound in-situ gel preparation with Chinese medicine active part.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a compound in-body gel preparation of effective parts of traditional Chinese medicines for pain relief and a preparation method thereof. Background technique [0002] Local pain can be due to various factors. Traditional Chinese medicine believes that "the general rule does not cause pain, and the pain leads to obstruction", which highly summarizes the pathogenesis and treatment of pain in traditional Chinese medicine. "Impedence leads to pain" is the first theory put forward by traditional Chinese medicine to treat pain diseases, and it is also the core mechanism used in clinical treatment of pain syndromes. There are many causes of "pain due to blockage". Qi blockage, blood stasis blocking collaterals, stagnation of cold pathogens, injury from falling, phlegm retention, food accumulation, etc. can all block Qi, blood, meridians, and viscera, resulting i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7024A61K31/05A61P29/00A61K31/12
Inventor 王建芳
Owner FOSHAN SOIN PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com