Entecavir and mannatide drug composition and preparation method thereof
A technology of mannan peptide and entecavir, which is applied in the field of medicine to achieve good synergistic effect and pharmacological activity, and enhance immunity
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Embodiment 1
[0036] Embodiment 1 Entecavir and mannan peptide pharmaceutical composition formulation prescription ratio
[0037] Table 1: The formulation ratio of entecavir and mannan peptide pharmaceutical composition for the treatment of viral hepatitis B, which can be used in both tablets and hard capsules.
[0038] The general manufacturing method for solid dosage forms is as follows:
[0039] 1. The proportioned entecavir, mannan peptide and excipients are mixed together;
[0040] 2. The homogeneous matter obtained in step 1 is further compacted into small particles;
[0041] 3. Lubricants such as magnesium stearate etc. are mixed with the granules obtained in the above step 2;
[0042] 4. The homogenate in step 3 is compressed into tablets or other solid dosage forms;
[0043] 5. If necessary, the coating liquid can be sprayed onto the tablet obtained in step 4 in the form of mist droplets.
[0044] When adopting hard capsule preparation, then the homogenate obtained in step 3 is d...
Embodiment 2
[0047] Prescription and preparation of embodiment 2 pharmaceutical composition tablet
[0048] prescription
[0049]
[0050] Preparation method: Weigh each component according to the prescription amount, mix thoroughly and evenly, granulate, and compress into tablets with a tablet machine.
Embodiment 3
[0051] Prescription and preparation of embodiment 3 pharmaceutical composition capsules
[0052] prescription
[0053]
[0054] Preparation method: weigh each component according to the prescription amount, sieve and dry, fully mix, granulate, and fill with hollow capsules to obtain capsules of the pharmaceutical composition.
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Abstract
Description
Claims
Application Information
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