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Antitumor traditional Chinese medicine composition as well as preparation and application thereof

A composition and anti-tumor technology, applied in the direction of anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., to achieve significant anti-tumor activity and good compatibility.

Active Publication Date: 2015-10-14
GUANGZHOU DONGLAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the treatment of cancer by traditional Chinese and Western medicine has been greatly developed, there is no particularly effective method to solve the problem of cancer treatment.

Method used

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  • Antitumor traditional Chinese medicine composition as well as preparation and application thereof
  • Antitumor traditional Chinese medicine composition as well as preparation and application thereof
  • Antitumor traditional Chinese medicine composition as well as preparation and application thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0069] Preparation method 1 of DL571 of the present invention: according to figure 1 According to the process design, the plant and non-plant Chinese medicines in the formula are treated with different solvents, different temperatures and different pH conditions, and the anti-tumor related components are fully extracted.

[0070] Concrete preparation steps are as follows:

[0071] 1. The botanical traditional Chinese medicine in the prescription, including: 3-15 grams of Danshen, 3-15 grams of Danpi, 3-15 grams of Niuqi, 3-15 grams of Chuangong, 3-15 grams of Acanthopanax, 3-3 grams of Scutellaria -12 grams, 3-15 grams of curcuma, 1-10 grams of saffron, 3-15 grams of peach kernel, 3-15 grams of barley kernel, 3-10 grams of lemon fruit, 5-15 grams of ginseng, 3-15 grams of cnidium, Mechanically pulverize, according to the ratio of 100 grams of traditional Chinese medicine: 200 milliliters of water, soak for 24 hours under the condition of 30 °C pH6.5, then increase the temper...

Embodiment 2

[0075] Preparation method 2 of DL571 of the present invention:

[0076] The traditional Chinese medicine in the prescription includes: Salvia miltiorrhiza 3-15 grams, Danpi 3-15 grams, Niuqi 3-15 grams, Chuangong 3-15 grams, Acanthopanax 3-15 grams, Scutellaria baicalensis 3-12 grams, Curcuma 3-15 grams, saffron 1-10 grams, peach kernel 3-15 grams, barley kernel 3-15 grams, lemon fruit 3-10 grams, ginseng 5-15 grams, cnidium 3-15 grams, artificial bezoar 0.005- 0.100 grams, 5-25 grams of tortoise shell, 3-10 grams of hippocampus, 3-15 grams of gallinaceous gold, 3-15 grams of purple river car (dry powder), add appropriate amount of water, and use traditional decoction, steaming, or add appropriate amount of food The wine is sealed and soaked for 1 month to 3 years, and then prepared into Chinese medicine decoction or medicinal wine.

Embodiment 3

[0078] Preparation method 3 of DL571 of the present invention:

[0079] The traditional Chinese medicine in the prescription includes: Salvia miltiorrhiza 3-15 grams, Danpi 3-15 grams, Niuqi 3-15 grams, Chuangong 3-15 grams, Acanthopanax 3-15 grams, Scutellaria baicalensis 3-12 grams, Curcuma 3-15 grams, saffron 1-10 grams, peach kernel 3-15 grams, barley kernel 3-15 grams, lemon fruit 3-10 grams, ginseng 5-15 grams, cnidium 3-15 grams, artificial bezoar 0.005- 0.100 grams, 5-25 grams of tortoise shell, 3-10 grams of hippocampus, 3-15 grams of gallinacea, 3-15 grams of Ziheche (dry powder), prepared into Chinese patent medicines according to the known preparation methods of Chinese patent medicines, including pills, Tablets, capsules, granules, oral liquids, lotions, external ointments and other dosage forms.

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Abstract

The invention provides an antitumor traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition adopts the following traditional Chinese medicine components: danshen root, tree peony bark, twotooth achyranthes root, Szechuan lovage rhizome, manyprickle acanthopanax root, baical skullcap root, curcuma zedoary, artificial bezoar, saffron, peach seed, coix seed, lemon, figwort root, tortoise shell, hippocamp, chicken's gizzard-membrane, dried human placenta and common cnidium fruit. The preparation method of the traditional Chinese medicine composition comprises the following steps: respectively extracting the traditional Chinese medicine components by using water and ethanol under the condition that the pH value is 3-7 and the temperature is 5-100 DEG C; and preparing concentrated liquid medicine or dry medicine powder by virtue of a concentration method. The traditional Chinese medicine composition provided by the invention has significant antitumor activity, does not have significant toxic or side effects on human, and can be applied to preparation of medicaments for preventing or resisting tumors.

Description

technical field [0001] The invention relates to a high-efficiency, low-side-effect anti-tumor traditional Chinese medicine composition, a preparation method thereof and an anti-tumor application thereof. Background technique [0002] Tumor is an abnormal lesion formed by the body under the action of various carcinogenic factors when a certain cell in a local tissue loses its normal regulation of its growth at the gene level, resulting in its clonal abnormal proliferation. The medical field generally divides tumors into benign and malignant tumors. Malignant tumors, also known as cancer, can occur in most tissues and organs of the body. Other parts of the body will also produce harmful substances, destroy the normal organ tissue structure, make the body dysfunction, and seriously threaten the life of the patient. [0003] The latest data from WHO shows that by 2020, the global cancer incidence rate will increase by 50%, that is, 15 million new cancer patients will be added e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/50A61K35/586A61K35/57A61K35/413A61K35/60
Inventor 刘誉
Owner GUANGZHOU DONGLAI BIOTECH CO LTD
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