Retina blood oxygen saturation measurement method based on fundus cameras

A retinal blood vessel and camera technology, applied in the field of blood oxygen saturation measurement, can solve the problems of not being able to understand the blood oxygen utilization capacity of the target tissue, the influence of skin light transmission, etc., and achieve the effect of saving equipment costs and expanding application functions

Inactive Publication Date: 2015-08-26
谢亚男
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Problems solved by technology

However, it is easily affected by the light transmittance of skin and other tissues at the detection site
[0004] The above two clinically commonly used blood oxygen measurement methods reflect the blood oxygen concentration in human aortic blood or peripheral circulating blood, not the blood oxygen saturation of the target tissue that we want to directly detect, let alone understand the actual situation of the target tissue. blood oxygen utilization capacity

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  • Retina blood oxygen saturation measurement method based on fundus cameras
  • Retina blood oxygen saturation measurement method based on fundus cameras
  • Retina blood oxygen saturation measurement method based on fundus cameras

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Embodiment Construction

[0033] Such as figure 1 As shown, the fundus retinal blood oxygen saturation measurement device based on the fundus camera includes:

[0034] 1. A commercial fundus camera 1, the fundus camera has a side hole 2, and its own flash includes visible light with a wavelength in the range of 380nm to 780nm, such as the Topcon series of fundus cameras;

[0035] 2. 50:50 splitting, 3;

[0036] 3. Two sets of filter devices 3 and 4, the filter devices are filter glass, through which light of a specific wavelength is passed;

[0037] 4. Two sets of image acquisition devices 6 and 7, wherein the image acquisition devices are high-resolution digital cameras with pixels greater than 20 million;

[0038] 5. Data analysis device 8, said data analysis device is a computer capable of performing image analysis.

[0039] Such as figure 2 As shown, the specific steps of the method for measuring retinal blood oxygen saturation are as follows:

[0040] Step 1: Use a fundus camera with a side ...

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Abstract

The invention relates to a retina blood oxygen saturation measurement method based on fundus cameras. Various shortcomings exist in an existing method. According to the method of the invention, refitting is carried out with an existing fundus camera as a platform, i.e., a 50:50 spectrometer is additionally installed so that fundus reflection light is averagely divided into two parts. Only the light with sensitive wavelength and the light with non-sensitive wavelength for oxyhemoglobin and deoxyhemoglobin are respectively allowed to pass through after being filtered and are respectively exposed to the two high-resolution digital cameras, so that two retina images under the same light source illumination intensity and the different wave length light conditions are obtained. Through analysis and data processing of the two retina digital images, light intensity values of retina nerve fiber layer image pixel points in an artery blood vessel, in a vein blood vessel and beside the blood vessels are obtained; and through analysis of the light intensity values in the blood vessel images, the proportion, namely the blood oxygen saturation, of the oxyhemoglobin in the retinal vessels is obtained. The retina blood oxygen saturation measurement method is easy to operate and does not bring wounds; and the retina artery blood oxygen saturation and the vein blood oxygen saturation can be obtained at the same time.

Description

technical field [0001] The invention relates to a method for measuring blood oxygen saturation, in particular to a method for measuring blood oxygen saturation in retinal arteries and veins. Background technique [0002] Many eye diseases and systemic diseases, such as glaucoma, retinitis pigmentosa, age-related macular degeneration, hypertension, diabetes, multiple sclerosis, etc., have different degrees of ischemia and hypoxia in fundus retinal tissue. As the condition worsens, there will be pathological manifestations such as atrophy of the retinal nerve layer, exudation of retinal tissue, edema, and hemorrhage, which will seriously affect vision. If the blood oxygen saturation and blood oxygen utilization of retinal tissue can be monitored early clinically, it will be of great help to the early diagnosis and treatment of these diseases. [0003] Currently, there are two clinical methods for measuring blood oxygen saturation: chemical method and optical method. The chem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455A61B3/14
CPCA61B5/1455A61B3/14A61B5/14555A61B5/7271
Inventor 谢亚男
Owner 谢亚男
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