A traditional Chinese medicine composition for treating senile insomnia and its preparation method

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation for the treatment of senile insomnia, can solve problems such as irritability, cognitive and psychomotor impairment, and failure to notice the pathological background of special populations of the elderly

Active Publication Date: 2017-11-24
SHAN DONG DONG E E JIAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although insomnia is not a critical illness, long-term lack of sleep will affect the patient's physical and mental health and bring great pain to the patient, especially the elderly. In severe cases, symptoms such as slow thinking and willpower will appear in varying degrees, and even suicide. Therefore, insomnia has become a social problem worthy of attention
[0004] Senile insomnia is a sleep disorder with complicated etiology. There are still few clinical studies on the disease, which reflects that there are not many syndrome differentiation and treatment in traditional Chinese medicine. Many patients regard it as a general insomnia treatment, and do not notice that the elderly are a special group of people. pathological background
At present, Western medicine mainly uses sedative and hypnotic drugs orally to treat insomnia. Although it has the advantages of safety, quick onset, and good tolerance, it is prone to accumulation and hangover phenomenon when taken by the elderly. If it is taken for a long time, its dependence will be greatly increased, and sudden It is easy to have adverse reactions such as nervousness, anxiety, irritability, cognitive and psychomotor impairment, insomnia rebound and withdrawal syndrome after stopping taking it, so it is not suitable for long-term use
There are many ways to treat insomnia with traditional Chinese medicine, but there is no clinical medicine for the treatment of insomnia in the elderly

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1: the preparation of capsule

[0048] Weigh each raw material according to the following weight: Rehmannia glutinosa 300g, Cornus 150g, Morinda officinalis 200g, Cistanche 300g, Ophiopogon japonicus 150g, Dendrobium 150g, Polygala 120g, Poria cocos 120g, Shichangpu 120g, Bupleurum 120g, Citrus aurantium 120g, 200g of peony root, 150g of roasted licorice, 150g of schisandra, 150g of cinnamon, 150g of aconite, 90g of coptis, 120g of donkey-hide gelatin, 200g of raw keel, 200g of raw oyster, 120g of Zhuru, 300g of fried jujube kernel, and 120g of piercing stone.

[0049] (1) Extract Shudi, Bupleurum, Poria, Ophiopogon japonicus, Dendrobium, Raw keel, Paeoniae Alba, Zhigancao, Raw oyster, Zhuru, Schisandra, Chuanchashi and Zhifuzi with water twice, add water 8 times the weight for the first time , decocted for 2 hours, added 6 times the weight of water for the second time, and decocted for 1 hour; combined the decoction liquid, filtered, and concentrated the fil...

Embodiment 2

[0052] Embodiment 2: the preparation of capsule

[0053] Prescription composition: Rehmannia glutinosa 200g, Cornus 120g, Morinda officinalis 150g, Cistanche 200g, Ophiopogon japonicus 100g, Dendrobium 120g, Polygala 100g, Poria cocos 100g, Shichangpu 100g, Bupleurum 100g, Citrus aurantium 100g, Paeoniae Alba 150g, Roasted licorice 100g, 100g schisandra, 100g cinnamon, 100g made aconite, 60g coptis, 100g donkey-hide gelatin, 150g raw keel, 150g raw oyster, 100g bamboo, 200g fried jujube kernel, 100g piercing stone.

[0054] Preparation Process:

[0055] (1) Extract Coptis chinensis, cornus, cinnamon, Morinda officinalis, Cistanche, Shichangpu, Citrus aurantii, fried jujube seed and Polygala 8 times with 70% ethanol, 1.5 hours each time, filter, and recover ethanol from the filtrate Afterwards, concentrate to a relative density of 1.08-1.12 (60°C), and spray-dry to obtain a fine powder for later use;

[0056] (2) Extract Shudi, Bupleurum, Poria, Ophiopogon japonicus, Dendrobi...

Embodiment 3

[0058] Embodiment 3: the preparation of powder

[0059] Weigh each raw material according to the following weights: Rehmannia glutinosa 100 g, Cornus 90 g, Morinda officinalis 100 g, Cistanche 100 g, Ophiopogon japonicus 90 g, Dendrobium 90 g, Polygala 10 parts, Poria cocos 80 g, Shichangpu 80 g, Bupleurum 80g, Citrus aurantium 80g, Paeoniae Alba 100g, Radix Glycyrrhizae 50g, Schisandra 50g, Cinnamon 50g, Aconite 50g, Coptis 30g, Ejiao 80g, Raw keel 100g, Raw oyster 100g, Zhuru 80 g, fried Suanzaoren 100 g, Chuanchashi 80 g; crush the above-mentioned raw materials, pass through an 80-mesh sieve, and pack separately to obtain the product.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating senile insomnia and a preparation method thereof, belonging to the field of traditional Chinese medicine. The composition is composed of the following raw materials in parts by weight: Rehmannia glutinosa, dogwood meat, Morinda officinalis, Cistanche deserticola, Ophiopogon japonicus, Dendrobium, Polygala, Poria, Shichangpu, Bupleurum, Citrus aurantium, Baishao, Zhigancao, Schisandra chinensis, cinnamon, aconite, Coptis chinensis, donkey-hide gelatin, raw keel, raw oyster, bamboo ru, fried sour jujube kernel, piercing stone. The invention has the functions of nourishing kidney yin and tonifying kidney yang, resolving phlegm, dispelling stasis and removing blood stasis, clearing heat, nourishing blood and soothing the nerves, and has a good effect on insomnia of the elderly.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating senile insomnia and a preparation method thereof. Background technique [0002] With the development of society and the improvement of people's living standards, the elderly gradually increase. According to the regulations of the World Health Organization, the elderly are those who are older than 60 years old. Epidemiological studies have shown that the incidence rate of adults in the community population is 10-20%, and about 50% of the elderly over 65 years old have chronic insomnia. rate showed a clear upward trend. [0003] The elderly are a special group in society. Senile insomnia is the insomnia that occurs in special groups. It is also called functional insomnia in the elderly. It is a common sleep disorder. Although insomnia is not a critical illness, long-term lack of sleep will affect the p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P25/20A61K35/02A61K35/36A61K35/618
Inventor 张淹周祥山田守生李士栋王春艳赵婷婷李民张路
Owner SHAN DONG DONG E E JIAO
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