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Traditional Chinese medicine composition with antithyroid cancer activity and its preparation method and application

A thyroid cancer and composition technology, which is applied in the field of traditional Chinese medicine composition with anti-thyroid cancer activity and its preparation, can solve the problems of large dosage, many impurity components, and slow onset of action, and achieve less dosage and scientific proportioning Reasonable and fast absorption effect

Active Publication Date: 2018-04-03
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology

However, the current reported antithyroid cancer drugs have a large dosage, many impurities, and slow onset of action.

Method used

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  • Traditional Chinese medicine composition with antithyroid cancer activity and its preparation method and application
  • Traditional Chinese medicine composition with antithyroid cancer activity and its preparation method and application
  • Traditional Chinese medicine composition with antithyroid cancer activity and its preparation method and application

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preparation example Construction

[0036] The preparation method of the Chinese medicine composition with antithyroid cancer activity of the present invention, it comprises the following steps:

[0037] (1) Take 12 grams of Radix Ginseng, 10 grams of Ophiopogon japonicus, 15 grams of Prunella vulgaris Prunella, 15 grams of Shanzi mushroom, and 10 grams of August Zha in parts by weight, add 15 times the volume of water of the total medicinal material weight, and soak 48 hours, then decocted and extracted 3 times, 2 hours each time, combined the extracts, concentrated, the concentrate was sequentially extracted with petroleum ether, chloroform, ethyl acetate, n-butanol, and the ethyl acetate and n-butanol extracts, the concentration dried extract;

[0038] (2) Take black nightshade in parts by weight, add acid water to soak for 24 hours, then decoct and extract 3 times, each time for 3 hours, then add alkaline water to adjust the pH value to 12, extract with chloroform to obtain chloroform extract, concentrate D...

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Abstract

The invention discloses a traditional Chinese medicine composition with antithyroid cancer activity, its preparation method and its application. The traditional Chinese medicine compound composition consists of 20-60 parts of Solanum solanum, 12-36 parts of Radix Ginseng, and 10-30 parts of Ophiopogon japonicus , 15 to 45 parts of Prunella vulgaris, 15 to 45 parts of Shanzi mushroom, and 10 to 30 parts of August Zha. Experimental results show that the traditional Chinese medicine composition with anti-thyroid cancer activity provided by the present invention has scientific and reasonable proportioning, rigorous medication, and has the effects of anti-cancer and detoxification, reducing phlegm and blood stasis, nourishing qi and nourishing yin, etc. It has a strong killing effect, can promote the production of tumor necrosis factor, improves the immunity of tumor patients, and has high safety and low toxic and side effects. The preparation method provided by the invention has stable quality, high content of extracted active ingredients, strong operability, and is suitable for large-scale industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine composition with antithyroid cancer activity and its preparation method and application. Background technique [0002] Thyroid carcinoma (thyroid carcinoma) is the most common malignant tumor of the thyroid gland. It is a malignant tumor derived from thyroid epithelial cells. Follicular adenocarcinoma (20%), but the prognosis is better, the tumor of follicular adenocarcinoma grows faster, is moderately malignant, easy to transfer through blood supply, undifferentiated carcinoma has a poor prognosis, and the average survival time is 3 to 6 months moon. Among thyroid cancers, papillary carcinoma is more common clinically. Clinically, the current drugs for the treatment of thyroid cancer are mainly chemical drugs. However, due to the high toxicity of chemotherapy drugs, they can not only kill tumor cells, but also non-selectively kill the body's own ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P35/00
Inventor 程海波周仲瑛沈卫星李柳孙东东徐长亮谭佳妮沈政洁吴东东
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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