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Traditional Chinese medicine composition capable of resisting breast cancer activity and preparation method and application thereof

An anti-breast cancer, composition technology, applied in the direction of drug combination, medical preparations containing active ingredients, anti-tumor drugs, etc., can solve the problems of insignificant curative effect, large dosage, and many impurity components, and achieve accurate and reliable curative effect. , Small dosage, scientific and reasonable effect

Active Publication Date: 2015-08-19
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology

However, the reported anti-breast cancer traditional Chinese medicine compound dosage is relatively large, there are many impurities, and the curative effect is not obvious.

Method used

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  • Traditional Chinese medicine composition capable of resisting breast cancer activity and preparation method and application thereof
  • Traditional Chinese medicine composition capable of resisting breast cancer activity and preparation method and application thereof
  • Traditional Chinese medicine composition capable of resisting breast cancer activity and preparation method and application thereof

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preparation example Construction

[0036] 2. the preparation method of the Chinese medicine compound composition with anti-breast cancer activity of the present invention, it may further comprise the steps:

[0037] (1) Take 15 grams of Leulu, 15 grams of Tiankuizi, 6 grams of Vinegar Bupleurum, 10 grams of Asparagus, 15 grams of Prunella vulgaris, 10 grams of August Zha, and add 12 times the volume of the total medicinal materials A large amount of ethanol was ultrasonically extracted 3 times for 2 hours each time, the extracts were combined and concentrated under reduced pressure to obtain a macroporous adsorption resin column on the concentrate, which was first eluted with water, and then washed successively with ethanol with a volume concentration of 20% to 60%. stripping; collecting ethanol eluent with a combined volume concentration of 40-60%, and concentrating to obtain the extract;

[0038] (2) Take the extract obtained in step (1), add lactose and cornstarch, mix evenly, add lubricant magnesium stearat...

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Abstract

The invention discloses a traditional Chinese medicine composition capable of resisting breast cancer activity and a preparation method and an application thereof. The traditional Chinese medicine composition is prepared by 15 to 45 parts of uniflower swisscentaury root, 15 to 45 parts of muskroot-like semiaquilegia root, 6 to 18 parts of vinegar processing radix bupleuri, 10 to 30 parts of asparagus fern, 15 to 45 parts of ajuga decumbens thunb, and 10 to 30 parts of fiveleaf akebia fruit. After proofing by pharmacological experiments, the traditional Chinese medicine composition capable of resisting the breast cancer activity has the advantages that the usage of the medicine is strict, the proportion is scientific and reasonable, and the effects of resisting cancers and detoxifying, dissipating phlegm and removing blood stasis, benefiting qi and nourishing yin and the like are realized; the strong killing function on the breast cancer inside and outside the human body is realized; the immunity of a tumor patient is improved, and the survival quality is improved; the safety is high, and the toxic and side effect is low. The preparation method has the advantages that the quality is stable, the content of extracted effective ingredients is high, the operability is high, and the preparation method is suitable for industrial and large-batch production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition with anti-breast cancer activity and its preparation method and application. Background technique [0002] Breast cancer is one of the most common malignant tumors in women. According to statistics, the incidence rate accounts for 7-10% of all kinds of malignant tumors in the whole body. It is second only to uterine cancer in women. Its incidence is often related to genetics, and 40-60 Between the ages, women before and after menopause have a higher incidence. Malignant tumors usually occurring in the glandular epithelium of the breast. It is one of the most common malignant tumors that seriously affects women's physical and mental health and even threatens their lives. Clinically, the current drugs for the treatment of breast cancer mainly include chemical drugs. However, due to the high toxicity of chemotherapy drugs, they c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P35/00
Inventor 程海波周仲瑛沈卫星李柳孙东东徐长亮谭佳妮沈政洁吴东东
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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