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Traditional Chinese medicine acupoint injection for treating migraine and preparation method of traditional Chinese medicine acupoint injection

An injection and migraine technology, applied in the field of medicine, can solve the problems of restricting the research and development of acupoint injection drugs

Inactive Publication Date: 2015-07-22
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still a lack of systematic mechanism research on acupoint injection for migraine, which limits the research and development of acupoint injection drugs, especially the research and development of traditional Chinese medicine acupoint injection drugs (Dong Shuzhong, Liu Yang. Simple application of acupoint injection in the treatment of migraine progress. Clinical Progress. 2013;15(22):11-12.)

Method used

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  • Traditional Chinese medicine acupoint injection for treating migraine and preparation method of traditional Chinese medicine acupoint injection
  • Traditional Chinese medicine acupoint injection for treating migraine and preparation method of traditional Chinese medicine acupoint injection
  • Traditional Chinese medicine acupoint injection for treating migraine and preparation method of traditional Chinese medicine acupoint injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 Chinese medicine acupoint injection for treating migraine and its preparation

[0037] Aroma flower 300g

[0038] White Tribulus 140g

[0039] Dong Lingcao 80g

[0040] preparation:

[0041] 1) Grind the dried fenugreek, Tribulus terrestris, and Radix japonicus, pass through a 200-mesh sieve, and measure the volume of the obtained powder;

[0042] 2) Add 3 times the volume concentration of 70% ethanol to the powder obtained in step 1), extract in a water bath at 80°C for 5 hours, mix the obtained extract, and measure the volume of the obtained extract;

[0043] 3) Add 3 times the volume of water to the extract obtained in step 2), let it stand overnight, and filter through a 0.45 μm microporous membrane to obtain the filtrate;

[0044] 4) Add citric acid to the filtrate obtained in step 3) to adjust the pH to 6.3;

[0045] 5) Sterilize the solution obtained in step 4), and pack it separately.

Embodiment 2

[0046] Example 2 Chinese medicine acupoint injection for treating migraine and its preparation

[0047] Aroma flower 300g

[0048] White Tribulus 140g

[0049] Dong Lingcao 80g

[0050] preparation:

[0051] 1) Grind the dried fenugreek, Tribulus terrestris, and Radix japonicus, pass through a 200-mesh sieve, and measure the volume of the obtained powder;

[0052] 2) Add 3 times the volume concentration of 70% ethanol to the powder obtained in step 1), extract in a water bath at 80°C for 5 hours, mix the obtained extract, and measure the volume of the obtained extract;

[0053] 3) Add 3 times the volume of water to the extract obtained in step 2), let it stand overnight, and filter through a 0.45 μm microporous membrane to obtain the filtrate;

[0054] 4) Add citric acid to the filtrate obtained in step 3) to adjust the pH to 6.5;

[0055] 5) Sterilize the solution obtained in step 4), and pack it separately.

Embodiment 3

[0056] Example 3 Chinese medicine acupoint injection for treating migraine and its preparation

[0057] Aroma flower 300g

[0058] White Tribulus 140g

[0059] Dong Lingcao 80g

[0060] preparation:

[0061] 1) Grind the dried fenugreek, Tribulus terrestris, and Radix japonicus, pass through a 200-mesh sieve, and measure the volume of the obtained powder;

[0062] 2) Add 3 times the volume concentration of 70% ethanol to the powder obtained in step 1), extract in a water bath at 80°C for 5 hours, mix the obtained extract, and measure the volume of the obtained extract;

[0063] 3) Add 3 times the volume of water to the extract obtained in step 2), let it stand overnight, and filter through a 0.45 μm microporous membrane to obtain the filtrate;

[0064] 4) Add citric acid to the filtrate obtained in step 3) to adjust the pH to 6.7;

[0065] 5) Sterilize the solution obtained in step 4), and pack it separately.

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Abstract

The invention relates to the field of medicine, in particular to a traditional Chinese medicine acupoint injection for treating migraine and a preparation method of the traditional Chinese medicine acupoint injection. The acupoint injection is prepared from the following raw materials in parts by weight: 20-40 parts of fragrant flower, 8-15 parts of tribulusterrestris and 5-16 parts of rabdosia rubescens; the preparation process comprises the following steps: crushing dried fragrant flower, tribulusterrestris and rabdosia rubescens, and filtering through a 200-mesh sieve; adding three times of 70% ethanol in volume, extracting in a water bath at 80 DEG C for 5 hours, and mixing extract liquids; adding three times of water in volume, standing over the night, and filtering through a 0.45micron microfiltration membrane; and adding a pH modifier to adjust the pH to be 6.2-6.8, sterilizing, and sub-packaging. The traditional Chinese medicine acupoint injection is used for preparing medicines for migraine. Animal experiment and clinical experiment researches show that the traditional Chinese medicine acupoint injection provided by the invention has a good treatment effect on migraine, and has good safety.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine acupoint injection for treating migraine and a preparation method thereof. Background technique [0002] Migraine is a common primary headache in clinical practice. It usually occurs in children and adolescence, and reaches its peak in young and middle-aged adults. The prevalence rate of women is higher than that of men. background. The main clinical manifestation of the disease is paroxysmal moderate to severe, pulsating headache, which is mostly hemilateral and usually lasts for 4 to 72 hours. Nausea, vomiting, light, sound stimulation or daily activities can all aggravate. [0003] The pathogenesis of migraine is not yet clear. At present, the pathogenesis of migraine in western medicine mainly has the following theories: [0004] Vascular theory: This theory believes that intracranial vasoconstriction causes migraine aura symptoms, followed...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61K9/08A61P25/06
Inventor 王玉琳
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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