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Traditional Chinese medicine composition for treating chronic ulcerative colitis and preparation method thereof

A technology for chronic ulcers and colitis, applied in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as inability to share or use antibiotics for a long time, affecting the quality of life of patients, and large side effects in the liver, and achieve improvement. Intestinal mucosa pathological changes, promoting ulcer healing and eliminating inflammatory mediators

Inactive Publication Date: 2015-05-27
倪春仙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among these drugs, sulfasalazine has serious side effects on the liver, and cannot be shared with antibiotics or used for a long time
Surgical treatment is to remove the entire colon, but due to many surgical complications, it seriously affects the quality of life of patients after surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] In the embodiment of the present invention, the raw materials are weighed: 15g of dodder, 10g of Morinda officinalis, 5g of Achyranthes achyranthes, 6g of Chuanduan, 16g of licorice, 9g of Yizhi, 4g of peach kernel, 12g of ebony plum, 6g of oridonium, 3g of Platycodon grandiflora, and Kochia scoparia 14g of seeds, 4g of eucalyptus leaves.

[0021] The specific steps of preparation include:

[0022] 1) Wash, cut and dry Cuscuta, Morinda officinalis, Achyranthes achyranthes, Licorice, Yizhi, peach kernel, ebony, Radix japonicus, Platycodon grandiflorum, Kochia chinensis, and Eucalyptus euphratica leaves, according to the above weight Weigh, reserve;

[0023] 2) Decoct Cuscuta, Morinda officinalis, Achyranthes bidentata, Licorice, Yizhi, peach kernel, ebony, and all traditional Chinese medicines in water 7-8 times the total weight, each time for 1-1.5h, filter and combine Concentrate the filtrate into an extract with a specific gravity of 1.0, add ethanol for alcohol pre...

Embodiment 2

[0027] In the embodiment of the present invention, raw materials were weighed: 22g of dodder seed, 14g of Morinda officinalis, 9g of Achyranthes achyranthes, 12g of Chuanduan, 22g of licorice, 14g of Yizhi, 9g of peach kernel, 18g of black plum, 11g of oridonium, 6g of Campanulaceae, Kochia scop 19g of seeds, 8g of eucalyptus leaves. The preparation steps are consistent with Example 1.

Embodiment 3

[0029] In the embodiment of the present invention, raw materials were weighed: 17g of dodder seed, 11g of Morinda officinalis, 6g of Achyranthes achyranthes, 8g of Chuanduan, 18g of licorice, 10g of Yizhi, 6g of peach kernel, 14g of ebony plum, 8g of Donglingcao, 4g of Platycodon grandiflora, and Kochia scoparia 16g of seeds, 5g of eucalyptus leaves. The preparation steps are consistent with Example 1.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic ulcerative colitis and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-22 parts of semen cuscutae, 10-14 parts of morinda officinalis, 5-9 parts of radix cyathulae, 6-12 parts of radix dipsaci, 16-22 parts liquorice, 9-14 parts of alpinia oxyphylla, 4-9 parts of peach seed, 12-18 parts of fructus mume, 6-11 parts of herba rabdosiae, 3-6 parts of platycodon grandiflorum, 14-19 parts of fructus kochiae and 4-8 parts of swamp mahogany leaf. The preparation method comprises the following steps: washing and cutting the various raw materials, drying, adding water into semen cuscutae and morinda officinalis for decocting for three times, concentrating, performing alcohol precipitation, and drying, thereby obtaining the extract A; adding ethanol into herba rabdosiae and platycodon grandiflorum for refluxing, and drying, thereby obtaining the extract B; merging the extract A and extract B, grinding, and mixing, thereby obtaining the material. The traditional Chinese medicine composition can achieve the effects of eliminating clinical symptoms, such as diarrhea, bloody purulent stool and abdominal pain, of patients suffering from chronic ulcerative colitis, obviously improving the intestinal mucose pathological change, eliminating inflammatory mediators and promoting ulcer healing, so that a good treatment effect is achieved. Moreover, the total effective rate is 96 percent, and adverse effects and toxic or side effects are not discovered.

Description

technical field [0001] The invention relates to, in particular, a traditional Chinese medicine composition for treating chronic ulcerative colitis and a preparation method thereof. Background technique [0002] Chronic ulcerative colitis is a chronic inflammatory disease of unknown etiology characterized by the mucosa and submucosa of the large intestine (mainly the rectum and colon). Ulcerative colitis is a chronic nonspecific inflammatory disease of the colon and rectum whose etiology is not yet clear, and the lesions are limited to the mucosa and submucosa of the large intestine. The lesions are mostly located in the sigmoid colon and rectum, and can also extend to the descending colon, or even the entire colon. The course of the disease is long and often recurrent. The disease is seen at any age, but it is most common in 20-30 years old. The cause of ulcerative colitis is still unknown. [0003] The current traditional treatment is basically taking drugs and injectio...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P1/04
Inventor 倪春仙
Owner 倪春仙
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