Traditional Chinese medicine composition for treating diabetic nephropathy, preparation method, traditional Chinese medicine preparation and application of traditional Chinese medicine composition

Abstract

The invention discloses a formula of a traditional Chinese medicine for treating diabetic nephropathy. The formula is characterized by involving the following raw materials by weight: 6 parts of astragalus roots, 3 parts of Pseudostellaria heterophylla, 2 parts of angelica, 2 parts of radix rehmanniae, 2 parts of cornus officinalis, 2 parts of Salvia miltiorrhiza, 3 parts of raw coix seeds, 2 parts of earthworm, 2 parts of Poria, and 2 parts of rhizoma alismatis. Directed at qi-yin deficiency, i.e. the traditional Chinese medicinal core pathogenesis of diabetic nephropathy, the formula has the efficacy of supplementing Qi and nourishing Yin, dispersing blood stasis and promoting dieresis, and is suitable for different-stage diabetic nephropathy with the main manifestations of soreness and weakness of waist and knees, weakness all over the body, edema, foaming urine, nausea, skin pruritus, limb numbness or acroanesthesia (or chilling), dark red tongue, thin or greasy tongue coat, thin pulse or rapid pulse and the like. The formula involves simple medicines and can achieve a special effect. Previous long-term clinical practice and scientific research prove that the formula can significantly reduce the urinary protein excretion rate, delay the renal function progress, effectively improve glucolipid metabolism, effectively control blood pressure, improve the quality of life of patients, and greatly decrease kidney disease end point events, and has the advantages of stable long-term effect and good safety.

Description

technical field [0001] The invention relates to the field of clinical treatment of traditional Chinese medicine, and more specifically, relates to a traditional Chinese medicine composition for treating diabetic nephropathy, a preparation method, a traditional Chinese medicine preparation and application. Background technique [0002] Diabetic nephropathy (DN) is one of the most serious and common chronic complications of diabetes. The World Health Organization predicts that the number of people with diabetes will exceed 48 million in 2030, with the resultant increase in the number of people with diabetic kidney disease. Diabetic nephropathy is the number one cause of chronic renal failure, accounting for about 40% of patients with end-stage renal failure. Once a patient develops microalbuminuria, renal damage develops rapidly, and most patients enter end-stage renal disease (ESRD) within a relatively short period of time, which will bring a heavy economic burden to individ...

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Problems solved by technology

[0005] At present, there are also reports on the clinical research on the prevention and treatment of diabetic nephropathy according to the syndrome differentiation of traditional Chinese medicine.

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