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Compound preparation of Dendrobium officinale for the treatment of tumor-related sleep disorders

A technology for Dendrobium officinale and sleep disorders, which is applied in the field of compound preparations of Dendrobium officinale, and achieves the effects of improving sleep, improving sleep disorders and having remarkable therapeutic effects.

Active Publication Date: 2017-09-15
ZHEJIANG JIGONGYUAN PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after studying its literature, it is found that the main purpose of the compound preparation is to stimulate the human body to further enhance immunity from the perspective of improving sleep. Therefore, it can be inferred that the compound preparation is aimed at ordinary insomnia patients, especially for cancer patients, especially those prone to breast cancer and lung cancer. Whether cancer patients with tumor-related sleep disorders can apply this compound preparation is unknown, because we know that different drugs will have incompatibility when used in combination. The risk is also unknown, and further program screening, experimental design and verification are required

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1: comparison of the preparation process of the compound preparation of dendrobium officinale

[0048] Experimental group 1: Take 25g of Dendrobium candidum, 15g of asparagus, 15g of Codonopsis pilosula, 12g of angelica, 12g of Rhizoma Chuanxiong, and 6g of licorice, add to 10 times of water and decoct 3 times, each time for 1 hour, filter under reduced pressure, combine the filtrates, and concentrate under reduced pressure to obtain herbal extracts;

[0049] Experimental group 2: take 25g of Dendrobium officinale, cut into sections to 2mm, add 10 times of water, decoct 3 times for 1 hour each time, filter under reduced pressure, and combine the filtrate; take 15g of crushed asparagus, 15g of Codonopsis pilosula, 6g of licorice, 12g of angelica, Chuanxiong 12g, decocted 3 times, 1 hour each time, collected the filtrate; combined the filtrates of the above two steps, concentrated under reduced pressure to obtain the medicinal material extract.

[0050] Experi...

Embodiment 2

[0055] Embodiment 2: the preparation (granule) of dendrobium officinale compound preparation

[0056] Take 250g of Dendrobium officinale, flatten and cut into sections to 2mm, add 8 times of water, decoct 4 times, each time for 1 hour, filter under reduced pressure, and combine the filtrate; take 150g of crushed asparagus, 150g of Codonopsis pilosula, 60g of licorice, add 10 times of water Decoct for 2 hours, then add 120g of crushed angelica and 120g of Rhizoma Chuanxiong, decoct for 1 hour, collect the filtrate; combine the filtrate and concentrate it under reduced pressure to a relative density of 1.20-1.30 to obtain 413g of extract thick paste; take 150g of walnut kernels and grind them to 200 mesh, The walnut kernel powder obtained above is mixed with the extract thick paste, and an appropriate amount of soluble starch is added for wet granulation to prepare granules.

Embodiment 3

[0057] Embodiment 3: the preparation (tablet) of dendrobium officinale compound preparation

[0058] Take 300g of Dendrobium candidum, flatten and cut into sections to 5mm, add 5 times of water, decoct 3 times, each time for 0.5h, filter under reduced pressure, and combine the filtrate; take 120g of crushed asparagus, 130g of Codonopsis pilosula, 80g of licorice, add 5 times of Boil in water for 1 hour, then add 110g of crushed angelica and 100g of Rhizoma Chuanxiong, cook for 0.5h, and collect the filtrate; combine the filtrate and concentrate it under reduced pressure to a relative density of 1.20-1.30 to obtain 324g of a thick extract; take 160g of walnut kernels and grind to 100 For this purpose, mix the walnut kernel powder obtained above with the thick paste of the extract, add appropriate amount of starch and dextrin to obtain wet granules, dry the granules, then add magnesium stearate, mix well, calculate the weight of the tablet, and press the tablet to obtain the tabl...

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Abstract

The invention provides a compound preparation of Dendrobium candidum for treating tumor-related sleep disorders, which is composed of Dendrobium candidum, walnut kernels, asparagus, Codonopsis pilosula, Angelica sinensis, Rhizoma Chuanxiong, and licorice, and the powder or extract obtained from the above raw materials is formulated into Medicines for improving the sleep of tumor patients, health products, or functional foods can be prepared with pharmaceutically acceptable auxiliary materials. The compound preparation provided by the invention has scientific and reasonable components and contents, synergistic effect, has the effects of calming the nerves, invigorating qi and nourishing blood, etc., and can significantly improve the physical discomfort caused by tumor pain and the adverse reactions caused by anti-tumor treatment. It is safe and effective. It has been verified by experiments that it has the most obvious effect on treating tumor-related sleep disorders for cancer patients, especially lung cancer patients.

Description

technical field [0001] The invention belongs to the technical field of medicine and health products, and relates to a compound preparation of Dendrobium candidum for treating tumor-related sleep disorders. Background technique [0002] Malignant tumor is currently one of the main diseases that seriously affect human health and threaten human life, and it is the first cause of death in our country. Cancer patients have many discomforts, among which sleep problems are one of the more prominent discomforts. Studies have shown that the sleep quality of malignant tumor patients is significantly lower than that of healthy people, and the vast majority of malignant tumor patients have varying degrees of sleep disturbance. We know that the effective treatment of tumors currently mainly includes surgery, chemotherapy, radiotherapy and hormone therapy; and in Davidson's study found that, regardless of the type of tumor, sleep disturbance occurred in cancer patients who underwent surg...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A23L33/00A61P35/00A61P25/20
Inventor 朱明旺胡江宁周祥李立雷汤郑静曹晓铃何厚洪闵会余永华
Owner ZHEJIANG JIGONGYUAN PHARMA
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