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A low-temperature and low-pressure freeze-drying method for notoginseng chewable tablets

A technology of low temperature and low pressure, drying method, applied in the direction of drying solid materials, drying solid materials without heating, promoting the preliminary treatment of solid materials drying, etc. problems, to achieve the effect of retaining the content of active ingredients, saving freeze-drying time, and low production costs

Active Publication Date: 2016-07-06
ZHEJIANG JIANFENG HEALTH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The notoginseng dried by ordinary methods, the drying temperature is too high, and long-term exposure to the air will lead to the destruction of active ingredients and effective ingredients
In addition, the dried or sun-dried Panax notoginseng is too hard, difficult to crush, inconvenient to use, and the taste is too bitter, which is difficult for many consumers to accept
However, due to the difficulty in transportation and storage of fresh Panax notoginseng, coupled with the restrictions of the purchasing season, and the taste is too bitter, the scope of use of Panax notoginseng is limited.
[0004] At present, there are also some patents in China that use freeze-drying technology to process fresh Panax notoginseng, and the analysis temperature is as high as 120°C, which makes it difficult to maintain the active ingredients of Panax notoginseng
[0005] When the inventor used the existing freeze-drying technology to freeze-dry the Radix Notoginseng tablets, he found that although the loss of R1, Rg1, Rb1 and other components could be reduced by using the existing freeze-drying technology, the Radix Notoginseng tablets after freeze-drying would be deformed or split or Bulging or white spots on the surface cannot keep the raw product intact, which affects the appearance and later sales of freeze-dried Panax notoginseng tablets
In addition, in some methods, panax notoginseng is boiled to kill enzymes before freeze-drying. Due to the existence of high temperature conditions, the loss of R1, Rg1, and Rb1 is also increased.

Method used

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  • A low-temperature and low-pressure freeze-drying method for notoginseng chewable tablets
  • A low-temperature and low-pressure freeze-drying method for notoginseng chewable tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A low-temperature and low-pressure freeze-drying method for notoginseng chewable tablets, comprising the following steps:

[0024] (1) Pretreatment: Remove the fibrous root, velvet root and notch of fresh Panax notoginseng to obtain the main root, wash with sterile water, and drain the water; The tablet is sprayed with an aqueous solution of tea polyphenols with a mass concentration of 10% and an aqueous solution of sucrose with a mass concentration of 20%, and the mass ratio of the Panax notoginseng tablets to the aqueous solution of tea polyphenols and aqueous sucrose is 2:1:1;

[0025] (2) Pre-freezing: place the notoginseng tablets obtained in step 1) in a vacuum desiccator, cool down to -35°C, and freeze the notoginseng tablets;

[0026] (3) Vacuum freeze-drying: evacuate the vacuum dryer to make the pressure 15Pa, keep it for 1.5 hours, heat it, and raise the temperature from -35°C to 0°C in 25 hours, then heat it again, and make the temperature from -35°C to 0°C ...

Embodiment 2

[0029] A low-temperature and low-pressure freeze-drying method for notoginseng chewable tablets, comprising the following steps:

[0030] (1) Pretreatment: Remove the fibrous root, velvet root and notch of the fresh Panax notoginseng root to obtain the main root, wash it with sterile water, and drain the water; The tablet is sprayed with an aqueous solution of tea polyphenols with a mass concentration of 5% and an aqueous solution of fructose with a mass concentration of 60%, and the mass ratio of the Panax notoginseng tablets to the aqueous solution of tea polyphenols and aqueous fructose is 1:1:1;

[0031] (2) Pre-freezing: place the notoginseng tablets obtained in step 1) in a vacuum desiccator, cool down to -30°C, and freeze the notoginseng tablets;

[0032] (3) Vacuum freeze-drying: evacuate the vacuum dryer to make the pressure 10Pa, keep it for 1 hour, heat it, and raise the temperature from -30°C to 0°C in 20 hours, then heat it again, and make the temperature from -30...

Embodiment 3

[0033] Embodiment 3 A low-temperature and low-pressure freeze-drying method of notoginseng chewable tablets, comprising the following steps:

[0034] (1) Pretreatment: Remove the fibrous root, velvet root and notch of fresh Panax notoginseng to obtain the main root, wash with sterile water, drain the water; slice to obtain Panax notoginseng slices with a thickness of 5mm, The tablet is sprayed with an aqueous solution of tea polyphenols with a mass concentration of 20% and an aqueous solution of sucralose with a mass concentration of 1%, and the mass ratio of the Panax notoginseng tablets to the aqueous solution of tea polyphenols and aqueous sucralose is 4:1:1;

[0035] (2) Pre-freezing: place the notoginseng tablets obtained in step 1) in a vacuum desiccator, cool down to -40°C, and freeze the notoginseng tablets;

[0036] (3) Vacuum freeze-drying: evacuate the vacuum dryer to make the pressure 20Pa, keep it for 2 hours, heat it, and raise the temperature from -40°C to 0°C i...

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Abstract

The invention discloses a low-temperature and low-pressure freeze-drying method of pseudo-ginseng chewable tablets. The low-temperature and low-pressure freeze-drying method comprises the steps of (1) preprocessing, namely cleaning fresh pseudo-ginseng main roots and draining off the moisture content, slicing and spraying tea polyphenol aqueous solution and sweet aqueous solution onto the pseudo-ginseng slices, (2) pre-freezing, namely putting the pseudo-ginseng slices obtained in the step (1) into a vacuum drier, reducing the temperature to the range of -30 to -40 DEG C and freezing the pseudo-ginseng slices, (3) vacuum freeze-drying, namely vacuumizing the vacuum dryer to keep the pressure within the range of 10-20Pa, keeping for 1-2 hours, heating to increase the temperature to 0 DEG C from the range of -30 to -40 DEG C within 20-30 hours, reheating, and increasing the temperature to 20 DEG C from 0 DEG C within 2-4 hours; taking out the obtained pseudo-ginseng chewable tablets from the vacuum dryer. The low-temperature and low-pressure freeze-drying method of the pseudo-ginseng chewable tablets is low in cost, and capable of effectively keeping the content of effective constituents of the prepared pseudo-ginseng chewable tablets and guaranteeing excellent freeze-dried product appearance and good taste.

Description

technical field [0001] The invention relates to a manufacturing method of notoginseng tablets, in particular to a low-temperature and low-pressure freeze-drying method of notoginseng chewable tablets. Background technique [0002] Sanqi has a planting history of more than 400 years. It is a pearl in the treasure house of Chinese medicine and a treasure recognized both at home and abroad. Panax notoginseng contains dozens of saponins, more than ten kinds of amino acids, more than ten kinds of trace elements, dozens of kinds of volatile oils, notoginseng polysaccharides, notoginseng flavonoids, and various physiologically active substances such as VB and VE necessary for human body. The main active ingredients are easy to decompose at high temperature, resulting in the loss of biologically active substances in Sanqi and reducing the efficacy of Sanqi. Modern medical and pharmacological studies have found that Panax notoginseng has obvious functions of dilating blood vessels, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): F26B1/00F26B5/06
Inventor 陆国胜於洪建
Owner ZHEJIANG JIANFENG HEALTH TECH
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