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Nutrient gel for sterilizing and healing wound surface and preparation method of nutrient gel

A nutritional gel and wound surface technology, applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problems of low grafting rate, cost and environmental pressure, and easy production of organic solvents and other issues, to achieve the effect of good skin compliance, promoting healing and recovery

Inactive Publication Date: 2015-03-11
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the application of amino acids in antibacterial materials at present. It has been reported in the literature that amino acids are introduced into chitosan by graft copolymerization, but the grafting rate of the products prepared by this method is low, and in the preparation process Easy to generate organic solvents, which puts pressure on both cost and environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The nutrient gel used for wound sterilization and promoting healing of the present invention is made of the following raw materials in weight percentage: 1% hydroxyethyl cellulose ether, 0.1% chitosan, 0.05% polyhexamethylene guanidine, and 1% glycerin , compound amino acid 0.1%, the balance is water; the compound amino acid is one or more of the essential amino acids for human body, including lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine acid, leucine and valine; the water is deionized water.

[0024] The method for preparing the nutrient gel for wound sterilization and promoting healing can be carried out as follows:

[0025] ① Weigh the hydroxyethyl cellulose ether in the above weight percentage, add it to water, and prepare the hydroxyethyl cellulose ether suspension;

[0026] 2. In the hydroxyethyl cellulose ether suspension of said step 1., add chitosan, polyhexamethylene guanidine, glycerol, and compound amino acids in the above weight per...

Embodiment 2

[0029] The nutrient gel used for wound sterilization and promoting healing of the present invention is made of the following raw materials in weight percentage: 2% hydroxyethyl cellulose ether, 0.2% carboxymethyl chitosan, polyhexamethylene biguanide hydrochloride 0.08%, glycerin 2%, compound amino acid 0.3%, and the balance is water; the compound amino acid is one or more of the essential amino acids for human body, including lysine, tryptophan, phenylalanine, methionine, threonine Amino acid, isoleucine, leucine, valine; The water is deionized water.

[0030] The method for preparing the nutrient gel for wound sterilization and promoting healing can be carried out as follows:

[0031] ① Weigh the hydroxyethyl cellulose ether in the above weight percentage, add it to water, and prepare the hydroxyethyl cellulose ether suspension;

[0032] ②In the hydroxyethyl cellulose ether suspension in the step ①, add carboxymethyl chitosan, polyhexamethylene biguanide hydrochloride, glyc...

Embodiment 3

[0035] The nutrient gel used for wound sterilization and promoting healing of the present invention is made of the following raw materials in weight percentage, 2.5% of hydroxyethyl cellulose ether, 0.3% of hydroxyethyl chitosan, and 0.1% of polyhexamethylene biguanide phosphate %, glycerin 3%, compound amino acid 0.5%, and the balance is water; the compound amino acid is one or more of the essential amino acids in the human body, including lysine, tryptophan, phenylalanine, methionine, threonine acid, isoleucine, leucine, valine; the water is deionized water.

[0036]The method for preparing the nutrient gel for wound sterilization and promoting healing can be carried out as follows:

[0037] ① Weigh the hydroxyethyl cellulose ether in the above weight percentage, add it to water, and prepare the hydroxyethyl cellulose ether suspension;

[0038] 2. In the hydroxyethyl cellulose ether suspension in the step 1., add the above-mentioned hydroxyethyl chitosan, polyhexamethylene ...

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PUM

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Abstract

The invention discloses nutrient gel for sterilizing and healing a wound surface and belongs to the technical field of anti-bacteria gel. The nutrient gel for sterilizing and healing the wound surface is prepared from hydroxyethyl cellulose, chitosan and derivatives thereof, guanidine polymers, glycerinum and compound amino acid. The hydroxyethyl cellulose serves as a gel substrate, the gel which is used for sterilizing and healing the wound surface and contains the guanidine polymers, the chitosan and derivatives thereof and the compound amino acid is prepared through a simple process, and the nutrient gel has good skin compliance, is non-irritant, has sterilization and anti-inflammation functions, provides a certain nutrition support for the wound surface, effectively promotes healing and recovery of the wound surface, has no side effects and is safe and environment-friendly.

Description

[0001] technical field [0002] The invention belongs to the technical field of antibacterial gel, and in particular relates to a nutrient gel for wound sterilization and healing promotion and a preparation method thereof. Background technique [0003] Various wounds on the surface of the human body are common symptoms that are unavoidable in daily life, manifesting various daily cuts, contusions, burns, and chemical burns, etc. The longer the wound healing is delayed, the less likely the healing scars will disappear For chronic refractory ulcers such as decubitus ulcers and various skin surface ulcers of diabetic patients, the rapid growth and repair of the surface epithelium is more needed. Therefore, the ideal therapeutic index for all kinds of skin wounds is to control secondary infection and promote rapid wound healing. For decades, scholars from all over the world have been committed to actively promoting wound repair through various therapies. With the deepening of r...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K31/722A61K31/785A61K31/155A61K9/06A61K47/38A61P17/02A61P31/04A61K31/198A61K31/405
Inventor 朱天钢刘尧周新钦
Owner HENAN HUIBO MEDICAL CO LTD
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