Oxiracetam compound

A hydrate and composition technology, applied in the field of oxiracetam hydrate and its preparation, to treat brain damage caused by physical and chemical factors, to achieve high purity and good stability

Active Publication Date: 2015-02-25
TIANJIN HANRUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The dosage range of Oxiracetam Injection marketed abroad is 2-8g per day, but there is no domestic experience of using less than 4g and higher than 6g

Method used

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Abstract

The invention belongs to the technical field of medicine, and specifically relates to an oxiracetam compound and a preparation method thereof. The provided oxiracetam compound contains a half of crystal water, and has the advantages of high purity, good stability, and excellent technology repeatability. The invention also relates to an application of oxiracetam in preparation of drugs for treating brain damages caused by physical and chemical factors, various cerebral anoxia, and chronic cerebral insufficiency.

Description

technical field The invention belongs to the technical field of medicine, and specifically relates to oxiracetam hydrate and a preparation method thereof. The invention also relates to using the composition of the hydrate to treat brain damage caused by physical and chemical factors, various brain hypoxia and chronic brain insufficiency Wait. It has a certain effect on dementia, shock, senile mental decline syndrome (such as memory loss, decreased adaptability, senile weakness and mental activity disorder, etc.), brain development of low-energy children, and improvement of memory and work efficiency of normal people. Background technique Oxiracetam (Oxiracetam, 1), the chemical name is 4-hydroxypyrrolidone-2-acetamide, which was synthesized in 1974 by Sikorbechem in Italy and listed in Italy in 1987. Domestically, oxiracetam has been widely used since it was launched in 1998. Currently, there are capsules, injections (small water injections) and other varieties. Oxiraceta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D207/273A61K31/4015A61P25/28
CPCC07D207/273
Inventor 严洁李轩
Owner TIANJIN HANRUI PHARMA
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