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Dropping pill with seaweed gel and agar as capsule wall material, and its production technology

A technology of gel drop pills and seaweed glue, which is applied in the directions of pill delivery, medical preparations with non-active ingredients, and pharmaceutical formulations, etc., can solve the problems of moisture absorption and deterioration, short validity period and unqualified quality of medicines.

Inactive Publication Date: 2015-02-11
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, because gelatin is a protein substance, it has strong hygroscopicity and can transfer the absorbed moisture to the internal medicine, causing the medicine to absorb moisture and deteriorate, resulting in unqualified quality and short validity period.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 1. The product formula of the seaweed gel dripping pills of the present invention (composed by weight percentage): 20.0% sodium alginate, 6.0% agar, 8.0% sorbitol and glycerol, 65.0% distilled water and 1% auxiliary The production process of dropping pills is as follows: mix 65.0% distilled water with 8.0% plasticizer and heat to 85°C, slowly mix 20.0% sodium alginate and 6.0% agar under constant stirring Add the mixed glue until a transparent solution is formed, then place it in a sandwich steamer and heat it at 85°C for 20 minutes to melt it into a uniform glue solution. Then use a filter cloth (150 mesh) to filter into the dipping pot (keep it in a water bath), degas at 85°C and 0.5 atm for 10 minutes, and remove the foam on the liquid surface naturally. Pour the prepared glue solution into the glue tank of the dripping pill experiment dripping machine, set the temperature of the curing agent at 15~20°C, the flow rate ratio of the glue solution and the dr...

Embodiment 2

[0024] Example 2 1. The product formula of the seaweed gel capsule of the present invention (composed by weight percentage): 16.0% sodium alginate, 8.0% agar, 8% xylitol, 67% distilled water and 1% auxiliary agent; capsule production The process flow is: mix 67% distilled water and 8% plasticizer and heat to 85°C, slowly add the weighed 16.0% sodium alginate and 8.0% agar mixture under constant stirring until a transparent solution, and then placed in a jacketed steam boiler, heated at 85°C for 20 minutes to make it melt into a uniform glue. Then use a filter cloth (150 mesh) to filter into the dipping pot (keep it in a water bath), degas at 85°C and 0.5 atm for 10 minutes, and remove the foam on the liquid surface naturally. Pour the prepared glue solution into the glue tank of the dripping pill experiment dripping machine, set the temperature of the curing agent at 15~20°C, the flow rate ratio of the glue solution and the drug solution at 1:2~4, and control the total The ...

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PUM

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Abstract

The invention belongs to the technical field of medicine and health food products research and development, and relates to a formula and a production technology of a dropping pill based on seaweed gel. The technology comprises the following steps: 1, weighing 10.0-30.0wt% of seaweed gel, 3.0-10.0wt% of agar and 2.0-4.0wt% of a plasticizer, putting the above raw materials in 70.0-85.0wt% of deionized water, and maintaining at 85DEG C for 30min to realize seaweed gel and agar dissolving; 2, degassing at 85DEG C under 0.5atm for 10min, adding the obtained degassed solution into a pill dropping machine, and dropping; and 3, curing dropping pills by a composite curing agent, drying, sorting, and packaging to obtain the dropping pill. The dropping pill has the advantages of reasonable formula, safe eating, drug absorption benefiting, wide source and low price of the raw materials, simple production process, and suitableness for industrialized production.

Description

technical field [0001] The invention relates to health food and medical capsules, in particular to a method for producing medicinal dripping pills with alginate. Background technique [0002] At present, the main raw material for the production of dripping pills in my country is gelatin, and gelatin comes from the bones and skins of animals (pigs, cattle), and its main component is protein. Once the production management of this capsule shell is not in place, there may be risks of infection of animal-derived diseases, heavy metals, etc. Most religious believers, lay Buddhists and vegetarians cannot accept capsule medicines from animals. In addition, because gelatin is a protein substance, it has strong hygroscopicity and can transfer the absorbed moisture to the internal medicine, causing the medicine to absorb moisture and deteriorate, resulting in unqualified quality and short validity period. [0003] With people's understanding of plant capsules and the transformation ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/36A23L1/29A23L33/00
Inventor 赖鹏翔刘旭黄建军谢卫东王相伟
Owner SHANDONG UNIV
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