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Traditional Chinese medicine composition for treating osteogenesis imperfecta

A technology of osteogenesis imperfecta and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, bone diseases, etc., can solve the problems of non-specific anti-cause therapy, reduce mental stress and pain, have no toxic side effects, significant effect

Inactive Publication Date: 2014-11-26
林祥波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific treatment for this disease in Western medicine, mainly to prevent fractures

Method used

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  • Traditional Chinese medicine composition for treating osteogenesis imperfecta
  • Traditional Chinese medicine composition for treating osteogenesis imperfecta
  • Traditional Chinese medicine composition for treating osteogenesis imperfecta

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1, 25 parts of astragalus, 13 parts of angelica, 7 parts of Chuanxiong, 10 parts of fried white peony root, 15 parts of Codonopsis pilosula, 19 parts of fried Atractylodes macrocephala, 10 parts of Poria cocos, 15 parts of wolfberry, 19 parts of dodder, 15 parts of psoralen, cinnamon Branch 7, Sangjisheng 13, Dipsacus 15, Shayuanzi 19, Rehmannia glutinosa 13, Eucommia 15, Morinda officinalis 7, Liu Jinu 7, Eclipta 10, Cyperus cyperi 10 , Zhigancao 7 parts.

Embodiment 2

[0033] Example 2, 30 parts of astragalus, 18 parts of angelica, 12 parts of Chuanxiong, 15 parts of fried white peony root, 20 parts of Codonopsis pilosula, 24 parts of fried Atractylodes macrocephala, 15 parts of Poria cocos, 20 parts of wolfberry, 24 parts of dodder, 20 parts of psoralen, osmanthus 12 parts of branch, 18 parts of Sangjisheng, 20 parts of Dipsacus, Shayuanzi, 18 parts of Rehmannia glutinosa, 20 parts of Eucommia, 12 parts of Morinda officinalis, 12 parts of Liu Jinu, 15 parts of Eclipta, 15 parts of Cyperus, 12 parts of licorice.

Embodiment 3

[0034] Example 3, 35 parts of astragalus, 23 parts of angelica, 17 parts of Chuanxiong, 20 parts of fried white peony root, 25 parts of Codonopsis pilosula, 29 parts of fried Atractylodes macrocephala, 20 parts of Poria cocos, 25 parts of wolfberry, 29 parts of dodder, 25 parts of psoralen, osmanthus Branch 17, Sangjisheng 23, Dipsacus 25, Shayuanzi 29, Rehmannia glutinosa 23, Eucommia 25, Morinda officinalis 17, Liu Jinu 17, Eclipta 20, Cyperus cyperus 20 , 17 parts of roasted licorice.

[0035] Below is the clinical statistical data of patient using medicine of the present invention:

[0036] 1. General information

[0037] From March to April 2013, a total of 400 outpatients were treated, and the patients were randomly divided into observation group and control group, including 187 males and 213 females, with a male to female ratio of 0.9:1. The oldest age was 30 years old, and the youngest age was 3 years old. The average age was 17 years old, the shortest disease course...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating osteogenesis imperfecta, which is prepared from the following raw material in certain proportion: astragalus membranaceus, angelica sinensis, rhizoma chuanxiong, parched white peony root, radix codonopsis, roasted rhizoma atractylodis macrocephalae, poria cocos, fructus lycii, semen cuscutae, fructus psoraleae, cassia twig, herba taxilli, dipsacus asperoids, flatstem milkvetch seed, prepared rehmannia root, cortex eucommiae, radix moridae officinalls, artemisia anomala, eclipta, rhizoma cyperi and radix liquiritiae. The traditional Chinese medicine composition has the effects of nourishing liver and kidney, replenishing blood, nourishing liver, tonifying middle-Jiao and Qi, promoting blood circulation to arrest pain, invigorating kidney and spleen, promoting bone reunion, and strengthening tendons and bones, and can effectively treat osteogenesis imperfecta.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating osteogenesis imperfecta. Background technique [0002] Osteogenesis imperfecta, also known as brittle bones, is a genetic disease caused by a defect in collagen synthesis due to mutations in the gene encoding type I collagen. Most of them are autosomal dominant inheritance, a few are autosomal recessive inheritance, and the incidence rate is about 1 / 10000. The common manifestations of this disease are increased bone fragility, progressive bone and joint deformities, blue sclera, dentin hypoplasia, hearing loss, osteoporosis, joint laxity, and spinal curvature, often resulting in serious illness and disability. The emergence of osteogenesis imperfecta not only seriously endangers the healthy growth of children, but also makes the relatives of the children enter a gloomy life. There is no specific treatment for t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P19/08A61P19/02A61P27/16A61P19/10
Inventor 林祥波
Owner 林祥波
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