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Antibacterial and anti-inflammatory Chinese herbal medicine compound lotion and preparation method thereof

An antibacterial and anti-inflammatory, Chinese herbal medicine technology, applied in the directions of anti-inflammatory agents, pharmaceutical formulations, topical antibacterial agents, etc., can solve problems such as unreported technology and products, and achieve the effects of low cost, improved utilization, and broad application prospects.

Active Publication Date: 2017-10-03
重庆伊士腾生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, the development and utilization of Coptidis ash has not been reported, especially the technology and products of using Coptidis ash to develop antibacterial and anti-inflammatory skin lotion have not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1 The preparation of Chinese herbal medicine compound lotion of the present invention

[0020]Coptis ash residue 25 kg, Sophora flavescens 17 kg, Phellodendron 8, Cnidium 14 kg, Smilax cocos 14 kg, Zanthoxylum bungeanum 8 kg, Baibu 8 kg, mint 0.8 kg, chlorhexidine acetate 2 kg, polysorbate 3 kg , 0.2 kilograms of sodium benzoate. The above seven herbs are decocted twice with water, 2 hours for the first time, 1 hour for the second time, filtered, combined filtrates, concentrated under reduced pressure to a clear paste with a relative density of 1.20-1.25 (50°C), and added ethanol to make the paste containing The alcohol content reaches 60% to 70%, let stand for 24 hours, filter, recover ethanol, then add polysorbate and stir evenly, and combine with the above-mentioned filtrate. Separately take chlorhexidine acetate, sodium benzoate and peppermint, respectively dissolve and filter with ethanol, add to the above-mentioned mixture in turn, add water to the spe...

Embodiment 2

[0021] Embodiment 2 The preparation of Chinese herbal medicine compound lotion of the present invention

[0022] Coptis ash residue 20 kg, Sophora flavescens 15 kg, Phellodendron 5, Cnidium 20 kg, Smilax cocos 20 kg, Zanthoxylum bungeanum 7 kg, Pepper 7 kg, Mint 1 kg, Chlorhexidine acetate 2 kg, Polysorbate 2.9 kg , 0.1 kilogram of sodium benzoate. Add the above seven herbs and decoct three times, the first time for 1 hour, the second time for 0.5 hours, the third time for 0.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.20-1.25 (50°C) , add ethanol to make the alcohol content reach 60% to 70%, let it stand for 12 hours, filter, recover ethanol, add polysorbate and stir evenly, and combine with the above-mentioned filtrate. Separately take chlorhexidine acetate, sodium benzoate and peppermint, respectively dissolve and filter with ethanol, add to the above-mentioned mixture in turn, add water to the spe...

Embodiment 3

[0023] Embodiment 3 The preparation of Chinese herbal medicine compound lotion of the present invention

[0024] Coptidis ash 30 kg, Sophora flavescens 20 kg, Phellodendron 5, Cnidium 15 kg, Smilax tuckahoe 15 kg, Zanthoxylum bungeanum 5 kg, Baibu 5 kg, mint 2 kg, chlorhexidine acetate 1 kg, polysorbate 1 kg , 1 kg of sodium benzoate. Add the above seven herbs and decoct three times, the first time for 1 hour, the second time for 1 hour, the third time for 0.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.20-1.25 (50°C) , add ethanol to make the alcohol content reach 60% to 70%, let it stand for 18 hours, filter, recover ethanol, add polysorbate and stir evenly, and combine with the above-mentioned filtrate. Separately take chlorhexidine acetate, sodium benzoate and peppermint, respectively dissolve and filter with ethanol, add to the above-mentioned mixture in turn, add water to the specified amount, st...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, particularly relates to an antibacterial and anti-inflammatory Chinese herbal medicine compound lotion and a preparation method thereof, and aims at solving the technical problem of providing an antibacterial and anti-inflammatory Chinese herbal medicine compound lotion with coptidis rhizome ash as a main raw material. According to the technical scheme, the antibacterial and anti-inflammatory Chinese herbal medicine compound lotion is prepared from the following raw materials by weight percent: 20-30% of coptidis rhizome ash, 15-20% of sophora flavescens, 5-10% of cortex phellodendri, 15-20% of fructus cnidii, 15-20% of smilax glabra, 5-10% of pepper, 5-10% of radix stemonae, 0.2-2.0% of mint, 1.0-3.0% of chlorhexidine acetate, 2-3% of polysorbate and the balance of sodium benzoate. The invention also provides a preparation method of a traditional Chinese medicine compound preparation. The Chinese herbal medicine lotion provided by the invention has a strong killing effect on various vulva and vaginal itching caused by pathogenic microorganisms such as staphylococcus aureus, escherichia coli, candida albicans and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an antibacterial and anti-inflammatory Chinese herbal medicine compound lotion and a preparation method thereof. Background technique [0002] After the skin is infected with bacteria, especially various fungi, various reactions such as inflammation and itching will occur. Although it can be sterilized by using various antibiotics, it is easy to produce drug-resistant bacteria. After long-term use, its antibacterial and anti-inflammatory effects are not ideal. The compound prepared by using antibacterial and anti-inflammatory Chinese herbal medicine is not easy to produce drug resistance because of the compound antibacterial ingredients. Sex; plus the high safety of Chinese herbal medicine, easy to be accepted by the market. At present, various skin lotions prepared with Chinese herbal medicines as raw materials, such as "Jieeryin" lotion (cnidi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61P31/02A61P29/00A61P17/04
CPCY02A50/30
Inventor 叶小利李学刚
Owner 重庆伊士腾生物科技有限公司
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