Liquid wound dressing used for wound healing and preparation method thereof

Abstract

The invention relates to a liquid wound dressing used for wound healing and a preparation method thereof. The liquid wound dressing adopts a polyurethane adhesive as a film forming material, takes chitosan as the filler, and employs laurocapram as a penetration enhancer. The pharmaceutical composition involves borneol, rosin, camphor, a lithospermum extract, a safflower extract, a frankincense extract and a myrrh extract. The preparation method includes: firstly dissolving the borneol, rosin and camphor in a solvent, then adding the polyurethane adhesive and chitosan, and then adding the concentrated solutions of lithospermum, safflower, frankincense, myrrh and other traditional Chinese medicines as well as laurocapram, mixing the materials evenly, then adding the mixture into water to perform dispersion emulsification, and then removing the solvent, thus obtaining the liquid wound dressing. With the characteristics of low alcohol content, good water resistance, and small wound irritation, the liquid wound dressing can be sprayed, and can be used for wound recovery in trauma treatment.

Description

technical field [0001] The invention relates to a medical dressing and belongs to the field of medical technology. Specifically, the present invention relates to a liquid wound dressing which is used for wound healing and has the effect of promoting wound healing and a preparation method thereof. Background technique [0002] The application of bandages in the medical field is very extensive, and it has the advantage of cheap, easy to use, but common bandages have poor air permeability, and are also inconvenient to use in some specific positions. At the same time, debonding sometimes occurs in the bonding between the boundary layer and the skin, and it is easy for dust, bacteria, moisture, etc. to enter the wound, causing infection and increasing the scar. The use of liquid wound dressings can solve the problem of ordinary wound dressings to a certain extent. The problem. [0003] CN 102166369A discloses a liquid band-aid and its preparation process, which consists of 1% t...

AI Technical Summary

Problems solved by technology

[0005] At present, the liquid bandages on the market generally have the problem of poor water resistance or containing a lot of alcohol

Materials with polyvinyl alcohol as the main film-forming matrix generally use water as the solvent. It is generally not highly cytotoxic when used as a film coating agent, but it is not water-resistant during use, and materials with water-resistant properties such as polyvinyl alcohol Vinyl butyral generally uses organic solvents such as ethanol, which has a bactericidal effect, but for open wounds, the use of high concentrations of ethanol will cause severe pain to the patient

At the same time, for different cells, high concentration of ethanol also has high cytotoxicity

Some products currently using spray-type liquids for wound disinfection and recovery do not contain ethanol and do not cause severe pain, but the products cannot form a protective film that blocks bacteria or prevents water

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