Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of Chinese patent medicine for treating rheumatic bone disease

A technology for rheumatism and bone disease and Chinese patent medicine, applied in the field of traditional Chinese medicine, can solve problems such as formulas that cannot be formed systematically

Inactive Publication Date: 2018-06-26
EAST CHINA UNIV OF SCI & TECH
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing drugs on the market for the treatment of rheumatic bone disease, although each has its own treatment principles, cannot form a systematic prescription group for the treatment of different disease courses

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of Chinese patent medicine for treating rheumatic bone disease
  • Preparation method of Chinese patent medicine for treating rheumatic bone disease
  • Preparation method of Chinese patent medicine for treating rheumatic bone disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] A preparation method of a Chinese patent medicine for the treatment of rheumatic bone disease, comprising the following steps:

[0072] (1) Preparation of alkaloids

[0073] The alkaloids include ephedra alkaloids and strychnium alkaloids;

[0074] Weighing the medicinal materials of ephedra or nuxychnium and pulverizing them (the process of preparing ephedra alkaloids or nuxychnium alkaloids is the same, but should be carried out separately), reflux extraction with ethanol; filtering, centrifuging, concentrating under reduced pressure; rotary steaming to dryness, Weigh to obtain ephedra extract or nuxychon seed extract. The mass percent of the ephedra alkaloids in the ephedra extract is 20%-70%; the mass percent of the nuxyse alkaloids in the nuxychonzi extract is 40%-95%.

[0075] (2) preparation of flavonoids

[0076] The flavonoids include licorice flavonoids, safflower flavones and drynaria flavonoids.

[0077] ①Preparation of licorice flavonoids

[0078] Glyc...

Embodiment 2

[0103] On the basis of Example 1, the effective part extracts prepared in step (4) of Example 1 were mixed uniformly, and then spray-dried. The moisture content of the dried material was 3% to 5%, and the cured rheumatoid arthritis was obtained after drying. The traditional Chinese medicine prescription of disease, add appropriate amount of silicon dioxide and mix according to conventional method at last, fill and make the capsule (every capsule 400mg) of embodiment 1 prescription one.

Embodiment 3

[0105] A preparation method of a Chinese patent medicine for treating rheumatic bone disease, the basic preparation steps are the same as in Example 1, but the difference between Example 3 and Example 1 is that glycyrrhizin is replaced by notoginseng saponin of equal quality.

[0106] The active part components of Example 3 are prepared according to the following effective part mass parts, marked as prescription two:

[0107]

[0108] The active part component of embodiment 3 can also be formulated according to the following effective part mass parts, marked as prescription two (I):

[0109]

[0110] The active part components of Example 3 can also be formulated according to the following effective part mass fractions, marked as prescription two (II):

[0111]

[0112] Carry out quality analysis to the prescription two described in embodiment 3, analysis method is as follows:

[0113] (1) Qualitative analysis of ephedra

[0114] Take an appropriate amount of ephedri...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine formula for treating a rheumatism bone disease. The traditional Chinese medicine formula contains three effective parts namely alkaloid, flavones and saponin, wherein the alkaloid comprises ephedra alkaloid and nux vomica alkaloid; the flavones comprise licoflavone, red flower flavone and drynaria rhizome flavone; the saponin comprises glycyrrhizin, medicinal cyathula root saponin and notoginsenoside; the traditional Chinese medicine formula is prepared by mixing at least one alkaloid, at least one flavone and at least one saponin according to at a certain ratio from the ephedra alkaloid, the nux vomica alkaloid, the licoflavone, the red flower flavone, the drynaria rhizome flavone, the glycyrrhizin, the medicinal cyathula root saponin and the notoginsenoside. A method for preparing Chinese patent medicine according to the traditional Chinese medicine formula for treating the rheumatism bone disease comprises the following steps: (1) preparing alkaloid; (2) preparing flavones; (3) preparing saponin; (4) preparing the components of the effective parts; (5) preparing the Chinese patent medicine: tablets or capsules for treating the rheumatism bone disease. The Chinese patent medicine prepared according to the traditional Chinese medicine formula for treating the rheumatism bone disease can be used for treating rheumatic arthritis, rheumatoid arthritis and arthralgia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and relates to a prescription of a traditional Chinese medicine, in particular to a preparation method of a Chinese patent medicine for treating rheumatic bone disease. Background technique [0002] Rheumatic diseases, commonly known as "rheumatism", are caused by wind, cold, dampness, and trauma invading the human body, forming arthralgia poison and attaching to human bones, thereby damaging bones and hard tissues related to bones, resulting in muscle, ligament, synovial bursa, tendon A type of disease caused by poor nutrient supply of membranes. Among rheumatic diseases, 99% are rheumatic bone diseases, which is one of the most common chronic bone diseases nowadays. As early as in ancient times, Chinese medicine had related descriptions of rheumatic diseases. "Rheumatism" belongs to the category of "arthritis" in traditional Chinese medicine. In "Su Wen Bi Lun", there is a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A61K9/48A61P29/00A61P19/08
Inventor 倪力军赵雯雯张立国吴婷婷谢婷赵丽丽马东升梁倩闫志慧曾婷苏星云
Owner EAST CHINA UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com