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Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula

A technology for rheumatic bone disease and traditional Chinese medicine, which is applied in the field of preparation of traditional Chinese medicine prescriptions and Chinese patent medicines, and can solve problems such as prescriptions that cannot form a system

Inactive Publication Date: 2014-10-15
EAST CHINA UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing drugs on the market for the treatment of rheumatic bone disease, although each has its own treatment principles, cannot form a systematic prescription group for the treatment of different disease courses

Method used

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  • Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula
  • Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula
  • Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] A method for preparing a Chinese patent medicine according to a traditional Chinese medicine prescription for treating rheumatic bone disease, comprising the following steps:

[0072] (1) Preparation of alkaloids

[0073] The alkaloids include ephedra alkaloids and strychnium alkaloids;

[0074] Weighing the medicinal materials of ephedra or nuxychnium and pulverizing them (the process of preparing ephedra alkaloids or nuxychnium alkaloids is the same, but should be carried out separately), reflux extraction with ethanol; filtering, centrifuging, concentrating under reduced pressure; rotary steaming to dryness, Weigh to obtain ephedra extract or nuxychon seed extract. The mass percent of the ephedra alkaloids in the ephedra extract is 20%-70%; the mass percent of the nuxyse alkaloids in the nuxychonzi extract is 40%-95%.

[0075] (2) preparation of flavonoids

[0076] The flavonoids include licorice flavonoids, safflower flavones and drynaria flavonoids.

[0077] ①P...

Embodiment 2

[0103] On the basis of Example 1, the effective part extracts prepared in step (4) of Example 1 were mixed uniformly, and then spray-dried. The moisture content of the dried material was 3% to 5%, and the cured rheumatoid arthritis was obtained after drying. The traditional Chinese medicine prescription of disease, add appropriate amount of silicon dioxide and mix according to conventional method at last, fill and make the capsule (every capsule 400mg) of embodiment 1 prescription one.

Embodiment 3

[0105] A method for preparing Chinese patent medicine according to the traditional Chinese medicine prescription for treating rheumatic bone disease, the basic preparation steps are the same as in Example 1, but the difference between Example 3 and Example 1 is that Glycyrrhizin is replaced by Panax notoginsenoside of equal quality .

[0106] The active part components of Example 3 are prepared according to the following effective part mass parts, marked as prescription two:

[0107]

[0108] The active part component of embodiment 3 can also be formulated according to the following effective part mass parts, marked as prescription two (I):

[0109]

[0110] The active part components of Example 3 can also be formulated according to the following effective part mass fractions, marked as prescription two (II):

[0111]

[0112] Carry out quality analysis to the prescription two described in embodiment 3, analysis method is as follows:

[0113] (1) Qualitative analysi...

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Abstract

The invention relates to a traditional Chinese medicine formula for treating a rheumatism bone disease. The traditional Chinese medicine formula contains three effective parts namely alkaloid, flavones and saponin, wherein the alkaloid comprises ephedra alkaloid and nux vomica alkaloid; the flavones comprise licoflavone, red flower flavone and drynaria rhizome flavone; the saponin comprises glycyrrhizin, medicinal cyathula root saponin and notoginsenoside; the traditional Chinese medicine formula is prepared by mixing at least one alkaloid, at least one flavone and at least one saponin according to at a certain ratio from the ephedra alkaloid, the nux vomica alkaloid, the licoflavone, the red flower flavone, the drynaria rhizome flavone, the glycyrrhizin, the medicinal cyathula root saponin and the notoginsenoside. A method for preparing Chinese patent medicine according to the traditional Chinese medicine formula for treating the rheumatism bone disease comprises the following steps: (1) preparing alkaloid; (2) preparing flavones; (3) preparing saponin; (4) preparing the components of the effective parts; (5) preparing the Chinese patent medicine: tablets or capsules for treating the rheumatism bone disease. The Chinese patent medicine prepared according to the traditional Chinese medicine formula for treating the rheumatism bone disease can be used for treating rheumatic arthritis, rheumatoid arthritis and arthralgia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and relates to a prescription of traditional Chinese medicine, in particular to a prescription of Chinese medicine for treating rheumatic bone disease and a preparation method thereof (hereinafter referred to as "Chinese patent medicine"). Background technique [0002] Rheumatic diseases, commonly known as "rheumatism", are caused by wind, cold, dampness, and trauma invading the human body, forming arthralgia poison and attaching to human bones, thereby damaging bones and hard tissues related to bones, resulting in muscle, ligament, synovial bursa, tendon A type of disease caused by poor nutrient supply of membranes. Among rheumatic diseases, 99% are rheumatic bone diseases, which is one of the most common chronic bone diseases nowadays. As early as in ancient times, Chinese medicine had related descriptions of rheumatic diseases. "Rheumatism" belongs to the category of "art...

Claims

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Application Information

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IPC IPC(8): A61K36/484A61K9/48A61P29/00A61P19/08
Inventor 倪力军赵雯雯张立国吴婷婷谢婷赵丽丽马东升梁倩闫志慧曾婷苏星云
Owner EAST CHINA UNIV OF SCI & TECH
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