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Automated renal evaluation systems and methods using MRI image data

A technology of image data and evaluation system, which is applied in the fields of measurement, image data processing, and image analysis using nuclear magnetic resonance image systems, which can solve problems such as comprehension damage, inability to measure functional reserves and recoverability, etc., to improve diagnostic evaluation tools, Effectiveness of diagnostic assessment tools

Inactive Publication Date: 2014-08-20
WAKE FOREST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The observed viability of renal function in response to RA-RT is attributed to an incomplete understanding of the pathophysiology of aRAS-associated CKD and the current inability to measure functional reserve or "recoverability" of distal renal tissue from "aRAS" damage "

Method used

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  • Automated renal evaluation systems and methods using MRI image data
  • Automated renal evaluation systems and methods using MRI image data
  • Automated renal evaluation systems and methods using MRI image data

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Embodiment Construction

[0083] The present invention will now be described more fully with reference to the accompanying drawings, in which embodiments of the invention are shown. However, this invention should not be seen as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. Like numbers refer to like elements throughout. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items. Broken lines indicate optional features or operations unless otherwise indicated. In the claims, the claimed methods are not limited to the order of any steps recited, unless so indicated therein.

[0084] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, singular forms such as "a" or "an" and "t...

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Abstract

Renal screening systems include a circuit configured to electronically analyze MRI image data of a subject to evaluate renal function and generate a renal-risk report for a plurality of different therapeutic agents based on renal responses to test doses of each of the agents.

Description

[0001] Statement of Government Funding [0002] This invention was made with government support under Grant Nos. R41AG030248 and R42AG030248 from the National Institutes of Health. The US Government has certain rights in this invention. [0003] related application [0004] This application claims the benefit and priority of US Provisional Patent Application Serial No. 61 / 545,431, filed October 10, 2011, the contents of which are incorporated herein by reference as if fully set forth herein. technical field [0005] The present invention relates to the use of MRI image data to assess the effects of nephropathy, disease or injury or therapy on the kidney. Background technique [0006] Atherosclerotic renal artery stenosis (aRAS) is increasingly recognized as a cause of chronic kidney disease (CKD) and end-stage renal disease. aRAS is also strongly associated with increased risk of cardiac events and mortality, with most of these effects likely attributable to associated...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055G06T7/00
CPCA61B5/004G01R33/50A61B5/055G01R33/5635A61B5/14542A61B5/015A61B5/0263A61B5/4848G01R33/5601A61M5/14G01R33/5608A61B5/201A61B5/4872G01R33/56366
Inventor C.A.哈米尔顿W.G.亨利M.S.爱德华兹M.V.罗科
Owner WAKE FOREST UNIV
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