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Application of compound ainsliaea fragrans champ extract in preparation of health products or drugs for prevention and treatment of liver injury

A kind of technology of apricot rabbit ear wind and extract, which is applied in application, food preparation, drug combination, etc.

Inactive Publication Date: 2014-07-23
HENAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many reports on the compound Xingxiang rabbit ear wind single drug Xingxiang rabbit ear wind and Atractylodes macrocephala at home and abroad. However, there are few reports on the compound Xingxiang rabbit ear wind. They mainly focus on pharmacological effects, clinical applications, and quality control. Related reports on antioxidant and hepatoprotective effects in vitro

Method used

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  • Application of compound ainsliaea fragrans champ extract in preparation of health products or drugs for prevention and treatment of liver injury
  • Application of compound ainsliaea fragrans champ extract in preparation of health products or drugs for prevention and treatment of liver injury
  • Application of compound ainsliaea fragrans champ extract in preparation of health products or drugs for prevention and treatment of liver injury

Examples

Experimental program
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Effect test

Embodiment 1

[0021] The ethanol extract of Compound Xingxiang Rabbit’s Ear Feng was extracted by the following method: take 200 g of dried Xingxiang Rabbit’s Ear Feng and 100 g of Atractylodes macrocephala (bleach), add 1200 mL of 60% ethanol, heat and reflux to extract twice, and filter for 2 h for the first time , the second time 1 h, the combined filtrates were concentrated and dried with a rotary evaporator to obtain 39.43 g of ethanol extract.

Embodiment 2

[0023] The ethanol extract of Compound Xingxiang Rabbit’s Ear Feng was extracted by the following method: take 300 g of dried Xingxiang Rabbit’s Ear Feng and 100 g of Atractylodes macrocephala (bleach), add 2400 mL of 70% ethanol, heat and reflux for three times, and filter for 1 h each time. The combined filtrates were concentrated and dried with a rotary evaporator to obtain 49.12 g of ethanol extract.

Embodiment 3

[0025] The compound Xingxiang Rabbit's Ear Fengshui extraction and alcohol precipitation extract is obtained by the following method: take 250 g of dried Xingxiang Rabbit's Ear Feng and 100 g of Atractylodes Rhizoma Atractylodes Rhizome (bleach), decoct twice with water, each time for 2 hours, combine the decoction, filter, Concentrate the filtrate to an extract with a relative density of 1.08 (60°C), let it cool, add ethanol to make the alcohol content 70%, let it stand for 24 hours, take the supernatant, and wash the precipitate twice with 70% ethanol. The supernatants were combined, ethanol was recovered, concentrated and dried to obtain 56.98 g of water-extracted and alcohol-precipitated extract.

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Abstract

The invention belongs to the technical field of traditional Chinese medicine extracts, and particularly to an application of a compound ainsliaea fragrans champ extract in preparation of health products or drugs for prevention and treatment of liver injury. According to the present invention, liver protection effects of the ethanol extract and the water extraction alcohol precipitation extract of compound ainsliaea fragrans champ are investigated and confirmed, and the extracts can be used for prevention and treatment of liver injury.

Description

[0001] technical field [0002] The invention belongs to the technical field of traditional Chinese medicine extracts, and in particular relates to the application of a compound Xingxiang rabbit ear wind extract in the preparation of health care products or medicines for preventing and treating liver damage. Background technique [0003] The liver is the central station of metabolism in the body. It is the largest and most important detoxification organ in the human body. It can protect the body from damage and has very important physiological functions. However, liver damage often leads to various serious liver diseases. [0004] Liver damage is the liver damage caused by the invasion of the liver by various factors (such as viruses, drugs, reagents, hypoxia and immune factors, etc.), leading to inflammation, liver fibrosis, liver cirrhosis, liver failure and other diseases It is a common disease that threatens human health with high morbidity and mortality. The clinic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/284A61P1/16A61P39/06A23L1/30
Inventor 康文艺崔雪靖连朋丽朱晓娣
Owner HENAN UNIVERSITY
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