Drug for intervening skin reaction after radiotherapy and preparation method thereof

Abstract

The invention discloses a cutireaction intervention medicine after radiotherapy and a preparation method thereof, and aims to solve the problem of prevention of cutireaction after radiotherapy. The preparation method is characterized by comprising the following steps: (1) melting yellow gelatin with a fistular onion stalk decoction to prepare gelatin beads for later use; (2) extracting volatile oil from ivy glorybind herb root and herba siegesbeckiae, collecting, mixing for later use, and taking decoction dregs for later use; (3) carrying out water extraction and alcohol precipitation on Cynachum uilfordii Hemsl, chalcanthite, papaya, Bulbophyllum inconspicuum Maxim, Sargassumthunbergii, petrel, Reed Rhizome, Magnolia amoena and the decoction dregs obtained in the step 1, and taking the supernate; (4) adding the supernate obtained in the step 3 into the gelatin beads obtained in the step 1; addition the mixed volatile oil obtained in the step 2, and evenly mixing to obtain a primary material; and (5) drying the primary material obtained in the step 4, pulverizing, and passing through a 100-mesh screen to obtain the medicinal powder. The clinical experiment proves that the medicine has the characteristics of favorable curative effect and higher safety when being used for preventing cutireaction after radiotherapy, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for intervening skin reaction after radiotherapy and a preparation method thereof. Background technique [0002] Tumor radiation therapy (radiotherapy) is a treatment of malignant tumors by using radiation such as α, β, γ rays produced by radioactive isotopes and x-rays, electron beams, proton beams and other particle beams produced by various x-ray therapy machines or accelerators. method. Radiation injuries of skin are the most common side effects of radiotherapy when a large area is irradiated or irradiated skin folds and moist areas. It is related to the skin's tolerance to radiation, the radiation source used, the irradiated area and the site. Skin reactions are divided into three degrees: ⑴First-degree reactions: erythema, burning and itching sensation, the skin gradually changes from bright red to dark red when the irradiation continues, and there wi...

AI Technical Summary

Problems solved by technology

(3) Grade III reaction: ulceration or necrosis, which invades the dermis, causes radiation damage, and is difficult to heal

[0003] At present, there is no specific method for clinical prevention of skin damage after radiotherapy. Most of them should pay attention to clean and dry local skin.