Traditional Chinese medicine perfusion fluid as well as preparation method and application thereof

A technology of perfusate and traditional Chinese medicine, which is applied in the directions of medical formula, drug delivery, drug combination, etc., can solve the problems of low cure rate of bovine ovarian disease infertility, few cases of treatment, and extensive production process, so as to improve people's life The effect of quality, simple production process and labor cost saving

Inactive Publication Date: 2014-07-09
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This can easily cause the disorder of the body's reproductive hormone regulation, making it difficult for cows to conceive
[0013] (2) In order to improve economic benefits, cattle farms and self-employed farmers use hormone therapy in large quantities and many times, which can easily cause damage to the body of cows
[0014] (3) Massive and repeated application of hormone therapy may easily cause hormone residues in meat and milk, threatening human health
Although the curative effect is definite, the production process is relatively extensive, and the quality standard needs to be continuously improved in order to carry out large-scale production
[0026] (2) There are reports of new-type pregnancy-promoting perfusate and aphrodisiac pregnancy aid in other related literatures. At present, there are some pharmacological studies, and the treatment effect is acceptable, but the number of treatment cases is small, and the efficacy needs to be further verified. The production process and quality The standard needs to be standardized, and it is still far from reaching the inclusion standard of "Chinese Veterinary Pharmacopoeia"
[0027] (3) The overall treatment effect of the existing traditional Chinese medicine for treating bovine ovarian disease infertility is not good. In other words, the cure rate of bovine ovarian disease infertility is low, and the conception rate is low

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] 1. Test animals:

[0059] From Lanzhou Chengguan Dairy Farm, Linze Dairy Farm, Qilihe Dairy Farm, Lanzhou Railway Dairy Farm, Lanlian Dairy Farm, Lanzhou Minority Dairy Farm, Xining Dairy Farm, Tianjin Dairy Farm, choose cows that have not been in estrus for more than 2 months after giving birth 514 dairy cows were treated as objects of treatment. The types of infertility determined by rectal examination were: 242 cases of persistent corpus luteum, 180 cases of ovarian quiescence, 74 cases of ovarian cyst, and 18 cases of ovarian atrophy. They were divided into groups and treated with different methods.

[0060] 2. Clinical examination:

[0061] Before treatment, rectally check the shape, size, texture, position and contraction response of the uterine horn, the shape, size, texture and corpus luteum of the ovary, etc.

[0062] 3. Laboratory examination:

[0063] Determination of plasma progesterone level in affected cattle; blood rheology detection; determinatio...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine perfusion fluid which comprises the following components in parts by weight: 80 parts of herba epimedii, 60 parts of actinolite, 60 parts of salviae miltiorrhizae, 60 parts of flos carthami, 60 parts of leonurus, 60 parts of angelica sinensis, 60 parts of astragalus membranaceus, 60 parts of semen cuscutae and 60 parts of peach kernels. The invention further provides a preparation method and application of the perfusion fluid. The perfusion fluid disclosed by the invention has the beneficial effects that (1) according to the actual production requirements of cattle rearing industry, a novel formula is formed to effectively solve the key link in actual production of cattle rearing industry: the ovary disease infertility of cows suitable for reproduction, so that the conception rate in estrus of cows suitable for reproduction is improved, and the conception rate reaches up to 82.04%; (2) according to the Chinese veterinarian acupoint theory, the medicine gives the maximum effect by different delivery manners: uterus perfusion or acupoint injection; (3) a novel preparation which not only can be perfused in uterus but also can be injected from acupoints is refined by virtue of a water extract and alcohol precipitate method by means of a modern pharmaceutical preparation technology, so that the existing production process is improved, and the purpose of quality control can be realized.

Description

[0001] technical field [0002] The invention relates to animal preparations, in particular to a traditional Chinese medicine perfusate and its preparation method and application. Background technique [0003] With the improvement of people's living standards in our country, animal husbandry has become one of the fastest growing industries in my country's agricultural field, and cattle breeding is one of the fastest growing industries in animal husbandry, playing an increasingly important role in the national economy. more important role. In particular, the breeding scale of beef cattle and dairy cattle is getting bigger and bigger, and the breeding level is gradually improving. According to the industry research information of China Industry Research Network, as of 2010, the stock of beef cattle in my country exceeded 123.532 million heads, and the total beef output ranked fourth in the world; tons, milk production ranks third in the world, becoming a major milk producing c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K9/08A61P15/08A61K33/26
Inventor 牛建荣张继瑜周绪正李冰魏小娟程富胜
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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