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Bacterial cellulose biological patch and manufacturing method thereof

A technology of bacterial cellulose and bacterial cellulose film, which is applied in the field of bacterial cellulose products, can solve the problems of inability to organically combine body tissues, local tissue inflammation, infection, etc., achieve the best tear resistance and shape maintenance ability, and excellent mechanical properties performance effect

Active Publication Date: 2014-06-18
HAINAN GUANGYU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these polymer patches only play a blocking role after being placed in the abdomen, and cannot be organically combined with body tissues. At the same time, as foreign bodies, they will cause local tissue inflammation and infection after being placed.

Method used

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  • Bacterial cellulose biological patch and manufacturing method thereof
  • Bacterial cellulose biological patch and manufacturing method thereof
  • Bacterial cellulose biological patch and manufacturing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment B

[0074] In order to compare the effect of the BC of the present invention as a biological patch, we use a patch of PP (polypropylene) material as a comparison. The following is a series of comparative tests of the BC patch of the embodiment of the present invention and the traditional polypropylene PP patch:

[0075] like figure 1 , 2 , which are schematic diagrams of transmission electron micrographs of the BC embodiment of the present invention and the traditional PP, respectively. The traditional PP polypropylene patch is woven from polypropylene monofilament fiber, which has good strength and rigidity. Its porosity reaches 85%, and its density is 18.9g / m 2 .

[0076] (1) Water absorption test:

[0077] Because PP has low wettability and is a material that basically does not absorb water, its moisture content was not measured. In this experiment, only the water absorption experiment was done on BC:

[0078] Weigh bacterial cellulose in a watch glass with constant weig...

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Abstract

The invention relates to a bacterial cellulose biological patch and a manufacturing method thereof. The biological patch comprises a bacterial cellulose film, namely BC film, wherein the polymerization degree of the bacterial cellulose ranges from 2000 to 20000, the crystal form of the cellulose crystal is I type, the crystallization index is 50-95%, and in cell parameters, a is equal to 0.815nm, b is equal to 1.025nm, c is equal to 0.832nm, and beta is equal to 85 degrees. The bacterial cellulose biological patch has excellent mechanical property, better biological fitness, better anti-adhesion property and antimicrobial property in the enterocoelia environment, and proper area can be conveniently obtained.

Description

technical field [0001] The invention relates to a bacterial cellulose product, more specifically, the invention relates to a medical bacterial cellulose and a manufacturing method thereof. Background technique [0002] Some surgical operations in the abdominal cavity require the use of a mesh with excellent balance of physiological and mechanical properties to repair fascia or tendon. Typical and common surgical diseases such as abdominal wall hernia have a high incidence rate of about 12% in the population of various countries. . Especially incisional hernia, because it can cause local chronic pain, abdominal distension and discomfort, as well as serious complications such as strangulated intestinal obstruction and intestinal perforation, often affects the quality of life of the patient for a long time, and even threatens the life of the patient. A mesh is used to repair the hernia. There have been more than ten years of large-scale use of patches in my country, and the d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/20A61L27/50A61L27/54C12P19/04C12R1/02
Inventor 奚廷斐赖琛张志雄盛立远钟春燕
Owner HAINAN GUANGYU BIOTECH
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