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Application of paeonol in preparing medicine for resisting eimeria tenella

A technology of Eimeria and paeonol, which is applied in the application field of paeonol in the preparation of anti-Eimeria tenella medicaments

Active Publication Date: 2014-05-14
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] So far, there has been no report that paeonol has anti-Eimeria tenella, and it is impossible to infer whether it has anti-Eimeria tenacia based on the known properties of paeonol

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Preparation of paeonol powder: take 5g paeonol (content not less than 99%) and 95g starch and mix well.

[0013] The usage and dosage of the powder: mix the above 100g powder into 100 kg of feed, and feed according to the daily food intake.

Embodiment 2

[0015] Preparation of paeonol water-soluble powder: Take 2.5 g paeonol (content not less than 99%) and 97.5 g glucose and mix well.

[0016] Usage and dosage of water-soluble powder: dissolve the above-mentioned 100g powder in 100 liters of water. Cut off the water for 2 hours before the treatment, and then feed according to the normal drinking water amount.

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PUM

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Abstract

The invention discloses application of paeonol in preparing a medicine for resisting eimeria tenella. Paeonol and acceptable auxiliaries are prepared to form powder; the powder is added into a feed, is uniformly mixed, and is used for feeding chicken according to a daily feeding amount; or paeonol water-soluble powder is prepared from paeonol, can be dissolved in water, and can be used for feeding chicken according to a daily feeding amount. Animal infection experiments prove that the anticoccidial index (ACI) of paeonol can be over 180, and paeonol has a good effect of resisting eimeria tenella.

Description

technical field [0001] The invention relates to a new application of paeonol, in particular to the application of paeonol in preparing anti-Eimeria tenella medicaments. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers intensive chicken production, and the annual economic loss caused by it is as high as 2.5 billion pounds. The most harmful of these is Eimeria tenella. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Paeonol, chemical name: 4-methoxy-2-hydroxyacetophenone, 2-hydroxy-4-methoxyacetophenone, 2-hydroxy-4-methoxyacetophenone, 2-hydroxyacetophenone -4-methoxyacetophenone; also known as paeonol and paeoniflorol, the molecular formula of this compound is C 9 h 10 o 3 , molecular weight 166.17, CAS accessio...

Claims

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Application Information

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IPC IPC(8): A61K31/12A61K31/222A61P33/02
Inventor 廖申权孙铭飞谢明权戚南山吴彩艳吕敏娜温列娜
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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