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Traditional Chinese medicine composition for treating sick sinus syndrome, coronary heart disease angina and arrhythmia and preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for arrhythmia, treatment of sinus syndrome and coronary heart disease angina pectoris, can solve the problems of large side effects, high price, and not being able to be used for a long time

Active Publication Date: 2014-04-23
雷允上药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine can only be used to inject atropine or other cardiac glycosides for sick sinuses. Although it can increase the heart rate immediately, it has serious side effects and cannot be used for a long time.
At present, Western medicine advocates the installation of a pacemaker for severe patients, but due to the high price, it is still difficult to popularize it in my country, and some data show that the fatality rate of foreign patients with a pacemaker is still 18% to 33%, and the risk is relatively high.

Method used

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  • Traditional Chinese medicine composition for treating sick sinus syndrome, coronary heart disease angina and arrhythmia and preparation method and application thereof
  • Traditional Chinese medicine composition for treating sick sinus syndrome, coronary heart disease angina and arrhythmia and preparation method and application thereof
  • Traditional Chinese medicine composition for treating sick sinus syndrome, coronary heart disease angina and arrhythmia and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] 1. The compound Chinese medicine is made from the following raw materials in parts by weight:

[0057] 1 part of musk, 1 part of toad venom, 20 parts of bezoar, 5 parts of borneol, 30 parts of red ginseng, 60 parts of Sanqi, 60 parts of amber, 30 parts of salvia miltiorrhiza, 40 parts of storax.

[0058] 2, the preparation method of the Chinese medicine compound described in above 1, it comprises the following steps:

[0059] 1) Extract 30 parts of Salvia miltiorrhiza with 20 times the amount of 50% ethanol once, 24 hours each time, combine the extracts, filter, recover ethanol, concentrate to a clear paste with a relative density of 1.10-1.15 (detection temperature 95°C) ;

[0060] 2), 30 parts of red ginseng, 60 parts of Panax notoginseng, and 60 parts of amber are pulverized into fine powder; mixed with the above-mentioned salvia miltiorrhiza and 1 part of toad venom, dried, and pulverized into fine powder;

[0061] 3), grind 20 parts of bezoar, 1 part of musk, and...

Embodiment 2

[0064] 1. The compound Chinese medicine is made from the following raw materials in parts by weight:

[0065] 2 parts of musk, 8 parts of toad venom, 30 parts of bezoar, 10 parts of borneol, 120 parts of red ginseng, 120 parts of Panax notoginseng, 40 parts of amber, 80 parts of salvia miltiorrhiza, 50 parts of storax;

[0066] 2. Preparation steps

[0067] 1) Extract 80 parts of the above-mentioned Salvia miltiorrhiza with 5 times the amount of 95% ethanol twice, each time for 1 hour, combine the extracts, filter, recover ethanol, concentrate to a relative density of 1.20-1.28 (detection temperature 95°C) clear ointment;

[0068] 2), 120 parts of red ginseng, 120 parts of Panax notoginseng, and 40 parts of amber are pulverized into fine powder; mixed with the above-mentioned salvia miltiorrhiza and 8 parts of toads, dried, and pulverized into fine powder;

[0069] 3), 30 parts of bezoar, 2 parts of musk, and 10 parts of borneol are ground into fine powder, mixed with the ab...

Embodiment 3

[0072] 1. The compound Chinese medicine is made from the following raw materials in parts by weight:

[0073] 12 parts of musk, 8 parts of toad venom, 10 parts of in vitro cultured bezoar, 15 parts of borneol, 100 parts of red ginseng, 80 parts of Panax notoginseng, 30 parts of amber, 120 parts of salvia miltiorrhiza, 10 parts of storax;

[0074] 2. Preparation steps

[0075] 1) Extract 120 parts of the above-mentioned Salvia miltiorrhiza with 10 times the amount of 85% ethanol for 3 times, each time for 1 hour, combine the extracts, filter, recover ethanol, concentrate to a relative density of 1.30-1.35 (detection temperature 95°C) clear ointment;

[0076] 2), 100 parts of red ginseng, 80 parts of Panax notoginseng, and 30 parts of amber are pulverized into fine powder; mixed with 8 parts of salvia miltiorrhiza and toads, dried, and pulverized into fine powder;

[0077] 3), 10 parts of in vitro cultured bezoar, 12 parts of musk, and 15 parts of borneol are ground into fine ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating sick sinus syndrome, coronary heart disease angina and arrhythmia and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from musk, venenum bufonis, bezoar, borneol, red ginseng, pseudo-ginseng, amber, the root of red-rooted salvia and storax. According to the theory of traditional Chinese medicine of syndrome differentiation, the raw materials of the composition are screened by a large number of experiments, are reasonably matched and are complementary, thus jointly realizing the effects of strengthening heart and tonifying qi, and activating yang so as to restore the pulse; the aromatic composition also has effects of inducing resuscitation and activating blood and easing pain, has good curative effect for bradycardia sick sinus syndrome, coronary heart disease angina and arrhythmia, has no toxic or side effects, has a scientific and reasonable preparation method, and realizes large scale industrial production.

Description

1. Technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating sinus node syndrome, coronary heart disease angina pectoris and arrhythmia, a preparation method and application thereof. 2. Background technology [0002] Heart disease is the number one killer of human health. 1 / 3 of the world's population death is caused by heart disease, while in my country, hundreds of thousands of people die of heart disease every year. With the improvement of living standards, people's diet structure changes, activity decreases, cholesterol intake and body mass index increase, all of which are risk factors for cardiovascular and cerebrovascular diseases. In recent years, the incidence of cardiovascular and cerebrovascular diseases in my country has been increasing year by year, and it is in the "window period" of the outbreak of cardiovascular and cerebrovascular ...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61P9/10A61P9/06A61K35/56A61K35/55A61K35/413A61K35/10A61K31/045A61K35/65
Inventor 杨方钰王恒斌叶华李全罗年翠黄韬
Owner 雷允上药业集团有限公司
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