Medicine for curing Children eczema and preparation method thereof

A technology for eczema and medicine, applied in the field of medicine for treating eczema and its preparation, can solve the problems of inconvenience of glucocorticoid, aggravation of eczema, easy recurrence and the like

Inactive Publication Date: 2014-04-16
张瑞萍
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The usual western medicine treatment is antihistamines and glucocorticoids, topical glucocorticoids have non-specific anti-inflammatory effect, the curative effect is definite, but it is easy to relapse
And if the child needs long-term treatment or the treated lesions are too large, systemic absorption of topical glucocorticoids may cause adverse reactions such as suppression of the hypothalamus-pituitary-adrenal axis (HPA) axis
In addition, acute eczema belongs to the acute stage of inflammation, and when there is exudation, cream or cream cannot be used for external use, and only water can be used for wet compress, which also causes the inconvenience of external use of glucocorticoids
Studies in recent years have also shown that the colonization rate of Staphylococcus aureus on the skin of patients with eczema is significantly higher than that of normal people, and the severity of skin lesions is positively correlated with the number of bacterial colonization. The exotoxin released by Staphylococcus aureus can induce and aggravate Eczema, and induce the expression of glucocorticoid β receptors, thereby inhibiting glucocorticoid α receptors, making T cells insensitive to glucocorticoids, affecting the efficacy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1, raw materials: Fangfeng 10g, honeysuckle 10g, Angelica dahurica 10g, arctium 10g, wild chrysanthemum 10g, Kochia chinensis 10g, Bauhinia bark 10g, salvia miltiorrhiza 10g, peach gum 10g, menthol 10g. Mix all the medicines, add water to decoct twice, combine the decoction, and apply the decoction to the affected area.

[0022] 1 Materials and methods

[0023] 1.1 General information

[0024] From December 2008 to December 2010, 104 children with eczema were randomly divided into two groups. The treatment group consisted of 51 cases, 28 males and 23 females, aged 0.5 to 5 years, with an average of (2.1±1.8 ) years old; 53 cases in the control group, 31 males and 22 females, aged 0.4 to 5.5 years, average (2±2.1). There was no statistically significant difference in gender and age between the two groups. The diagnostic criteria of eczema refer to "Clinical Dermatology", and no glucocorticoids or antihistamines have been used within 2 weeks before treatment. ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a medicine for curing the Children eczema and a preparation method of the medicine, and aims to cure the eczema. The medicine is characterized by being prepared form the following Chinese herbs in equal weight ratio: radix sileris, honeysuckle, radix angelicae, fructus arctii, flos chrysanthemi indici, fructus kochiae, cortex kadsurae radicis, salvia miltiorrhiza, peach gum and menthol. The preparation method of the medicine comprises the following steps: extracting volatile oil from radix sileris, honeysuckle, flos chrysanthemi indici and fructus kochiae, adding extract liquor of radix angelicae, fructus arctii, cortex kadsurae radicis, salvia miltiorrhiza water and menthol into peach gum for stirring and heating, and finally mixing the volatile oil with the mixture. Clinical experiments prove that the medicine has the characteristics of good therapeutic effect and higher safety and is worthy of clinical application and promotion.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for treating eczema and a preparation method thereof. Background technique [0002] Eczema is a common chronic, relapsing, and inflammatory skin disease in children. It is caused by a variety of internal and external factors, and is related to the imbalance of skin barrier function, atopic constitution of children, and allergic reactions mediated by food and environmental allergens. The disease has obvious itching and repeated illnesses, which seriously affects the quality of life of children and their parents, especially the quality of sleep. The usual western medicine treatment is antihistamines and glucocorticoids. Topical glucocorticoids have non-specific anti-inflammatory effects and definite curative effect, but they are prone to relapse. And if the child needs long-term treatment or the treated lesions are too large, systemic absorption of topical gl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P17/00A61P37/08
Inventor 张瑞萍
Owner 张瑞萍
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products