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Traditional Chinese medicinal composition for treating allergic rhinitis

A technology for allergic rhinitis and composition, which is applied in the field of traditional Chinese medicine composition for the treatment of allergic rhinitis, to achieve the effects of reducing the incidence of adverse reactions, significant clinical curative effect, and reducing the dosage of western medicine

Active Publication Date: 2014-04-02
NANTONG FINC PHARMA CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Relevant research data show that the drug is sprayed into the nasal cavity, 2 presses per nostril each time, 2 times a day, 50 μg per press, the clinical effective rate is over 75%, but the incidence of adverse drug reactions is 12%

Method used

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  • Traditional Chinese medicinal composition for treating allergic rhinitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Herbal medicine prescription: 25 parts of Sophora japonica, 36 parts of dew hive, 18 parts of Huoxiang, 18 parts of Tribulus, 25 parts of Cortex Phellodendri, 8 parts of Large Thistle, 8 parts of Angelica dahurica, 25 parts of Dandelion, 25 parts of Viola, 18 parts of Prunella vulgaris.

[0018] Preparation process: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 1.5 hours, and add water for the second time to 8 times the weight of the medicinal materials amount, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C to an extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°...

Embodiment 2

[0020] Herbal medicine prescription: 22 parts of Sophora japonica, 42 parts of dew hive, 20 parts of Huoxiang, 20 parts of Tribulus, 30 parts of Cortex Phellodendri, 10 parts of thistle, 10 parts of Angelica dahurica, 23 parts of Dandelion, 27 parts of Prunella vulgaris, 22 parts of Prunella vulgaris.

[0021] Preparation process: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 1.5 hours, and add water for the second time to 8 times the weight of the medicinal materials amount, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C to an extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa...

Embodiment 3

[0023] Herbal medicine prescription: 30 parts of Sophora japonica, 30 parts of dew hive, 22 parts of Huoxiang, 15 parts of Tribulus, 23 parts of Cortex Phellodendri, 6 parts of Large Thistle, 8 parts of Angelica dahurica, 28 parts of Dandelion, 30 parts of Viola, 17 parts of Prunella vulgaris.

[0024] Preparation process: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 1.5 hours, and add water for the second time to 8 times the weight of the medicinal materials amount, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C to an extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°...

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating allergic rhinitis. The traditional Chinese medicinal composition comprises the following Chinese herbal raw materials in part by weight: 20-30 parts of flos sophorae, 30-42 parts of nidus vespae, 15-22 parts of agastache rugosus, 15-22 parts of caltrop, 20-30 parts of golden cypress, 6-12 parts of circium japonicum, 6-12 parts of radix angelicae, 20-30 parts of dandelion, 20-30 parts of philippine violet herb and 15-22 parts of selfheal. The traditional Chinese medicinal composition has a significant, stable and long-lasting clinical effect on the allergic rhinitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating allergic rhinitis. Background technique [0002] Allergic rhinitis is an inflammation of the nasal mucosa and submucosal tissue, induced by allergic or non-specific stimuli such as pollen, fungi, animal fur, food, drug contact, and climate change. The disease has the characteristics of repeated and frequent outbreaks, high incidence and difficult to cure. Many patients have loss of appetite due to poor sense of smell or sleep, which will have a great impact on work and life. If they die for a long time, the disease will continue to develop, or induce sinusitis, nasal polyps, allergic asthma, and sleep apnea syndrome. , coronary heart disease, myocardial infarction, hypertension, cerebrovascular accident and other diseases. The pathogenesis of allergic rhinitis has not been fully understood....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P11/02A61P37/08A61K35/64
CPCA61K9/1652A61K35/63A61K36/185A61K36/232A61K36/28A61K36/288A61K36/489A61K36/532A61K36/536A61K36/756A61K36/86A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 张霞
Owner NANTONG FINC PHARMA CHEM
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