Pharmaceutical composition for treatment of hydrosalpinx and preparation method thereof

Abstract

The invention relates to a pharmaceutical composition for treatment of hydrosalpinx and its preparation method. The pharmaceutical composition is basically composed of the following herbal components or their extracts: Radix Rehmanniae Preparata; Radix Paeoniae Alba; Salvia miltiorrhiza; Angelica; Radix Rehmanniae; Herba Patriniae; Arisaema erubescens; dandelion; poria; Solanum nigrum; coix seeds; Dioscorea septemloba; medlar; radix ophiopogonis; bamboo shavings; bighead atractylodes rhizome; Curcuma aromatica; Cyathula officinalis; and Sargentodoxa cuneata. The preparation method comprises the steps of: (1) weighing the herbal components, and mixing them to obtain a mixture; and (2) adding a pharmaceutically acceptable carrier into the mixture, and mixing them, thus obtaining the pharmaceutical composition. The pharmaceutical composition provided by the invention not only has significant treatment effects on hydrosalpinx, can quickly solve symptoms caused by hydrosalpinx and the adverse effects of hydrosalpinx on IVE-ET, but also has no adverse impact on human body endocrine, ovary and the like, is simple, effective, and cheap, thus being easy to use in a wide range.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicinal composition for treating hydrosalpinx and a preparation method thereof. Background technique [0002] Hydrosalpinx is a common type of pelvic inflammatory disease (PID), and it is also one of the main indications for IVF-ET. However, patients with hydrosalpinx directly receive IVF-ET (in vitro fertilization and embryo transfer) with poor efficacy , the reason may be that the embryotoxic effect of water accumulation reduces the embryo implantation rate and pregnancy rate, and increases the miscarriage rate; or the uterine cavity reflux of water accumulation has a mechanical washing effect on the embryo, which affects the implantation of the embryo, so IVF- It is necessary to pretreat the hydrosalpinx before ET. [0003] So far, the pretreatment methods for hydrosalpinx before IVF-ET are mainly various surgical interventions, including salpingectomy, salpin...

AI Technical Summary

Problems solved by technology

Laparoscopic salpingectomy may destroy the vascular network in the mesosalpinx of the affected side, thereby affecting the blood supply of the corresponding ovary, resulting in poor response of the ovary during ovulation induction; salpingostomy may cause recurrence of hydrops, and only Limited to patients with mild hydrosalpinx; tubal ligation and proximal tubal embolization may form tubal cysts leading to torsion, and proximal tubal embolization may affect the internal environment of the uterine cavity and even induce uterine contractions due to foreign bodies in the uterus during pregnancy; and The above operations are relatively complicated, and the patients need general anesthesia and the cost is high

Ultrasound-guided transvaginal hydrosalpinx aspiration through the posterior fornix is ​​a simple, fast and effective method, but hydrosalpinx aspiration cannot solve the problem of rapid recurrence of hydrosalpinx in the fallopian tube cavity, and the hydrosalpinx will recover within a few hours undisturbed

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