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Test paper for detecting carbon dioxide and preparation method of test paper

A technology of carbon dioxide and test paper, which is applied in the field of clinical medicine and environmental hygiene monitoring, can solve problems such as death, high cost of equipment, and serious harm to patients, and achieve the effects of convenient use, sensitive detection, and low cost

Inactive Publication Date: 2014-02-05
江苏德威兰医疗器械股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, in clinical operations, it is very important to quickly and accurately determine the position of the endotracheal tube in the process of first aid, resuscitation and anesthesia. Serious harm or even death. Currently, the most effective identification method is to detect carbon dioxide in exhaled air. In most cases, it is detected by instruments. However, the instruments are expensive and inconvenient to carry and use.
There is also a method to detect the concentration of carbon dioxide in the exhaled breath by means of chemical discoloration in foreign countries, but the color change of the indicator has a small contrast and is difficult to observe

Method used

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  • Test paper for detecting carbon dioxide and preparation method of test paper
  • Test paper for detecting carbon dioxide and preparation method of test paper

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 2

[0022] Example 1 Preparation of test paper for carbon dioxide detection and screening of parameters

[0023] Experiment 1: Prepare test paper 1-20 for carbon dioxide detection according to the following steps:

[0024] A: Dissolve 1g of ethyl cellulose in 15mL of acetone, stir at high speed for 1h, and mix the solution thoroughly; add 0.1g of bromothymol blue, 0.05g of bromocresol purple (this The color of the solution is yellow), 0.1mL of 2-ethylhexyloxypropylamine (yellow turns purple when just adding a drop), 0.2g of sodium sulfate decahydrate, 0.2mL of polyethylene glycol 600, 0.2ml of Distilled water, 0.2g of calcium carbonate, 0.2g of silicon dioxide, stirred for 1 hour (purpose: grinding and mixing evenly), then put the solution in a closed container, and let it stand at a certain temperature for a period of time.

[0025] B: Prepare a 0.05mol / L sodium hydroxide solution, put the paper with good water absorption into the solution for 30 minutes, and then dry it in an o...

Embodiment 2 2

[0034] Example 2 Carbon dioxide detection with test paper sensitivity detection

[0035] Put the carbon dioxide detection test paper 1-40 prepared in Example 1 into airtight containers respectively, and pass into the container a carbon dioxide gas with a concentration of 5% (the gas composition is the same as the human breath composition), and detect its discoloration (by dark Green becomes lemon yellow) required time, the result is as shown in the table below:

[0036] Table 2

[0037]

[0038]

[0039] It can be seen from the above experimental data that the sensitivity of the test paper has a great relationship with the standing temperature and the standing time in step A. When the standing temperature in step A is 30°C-40°C, the test paper has better sensitivity, when the standing time is 5min-10min, the test paper has better sensitivity, and when the temperature is 33°C, standing When the time is 8 minutes, the test paper has the highest sensitivity.

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Abstract

The invention belongs to the field of clinical medicine and environmental health monitoring and particularly relates to test paper for detecting carbon dioxide and a preparation method of the test paper. The test paper is prepared by using a following method comprising the steps: A, dissolving ethyecellulose in acetone and agitating; adding bromothymol blue, bromcresol purple, 2-ethyl hexyloxy propylamine, sodium sulfafe decahydrate, polyethylene glycol 600, distilled water, calcium carbonate and silicon dioxide; agitating and mixing uniformly so as to obtain a solution; putting the solution into a closed container and standing for a period of time at a certain temperature condition; B, namely preparing a sodium hydroxide solution and putting a piece of paper with the good water-absorbing quality into the solution to be immersed sufficiently; then drying the paper in a drying oven; C, adding a certain amount of the distilled water in the solution obtained in the step A until the solution becomes bluish violet; dripping the solution to the paper treated in the step B and putting the paper into the drying oven to the dried. The test paper is convenient to use, low in construction cost and sensitive in detection, and can be widely applied to the field of the clinical medicine and the environmental health monitoring.

Description

technical field [0001] The invention belongs to the fields of clinical medicine and environmental sanitation monitoring, and more specifically relates to a test paper for carbon dioxide detection and a preparation method thereof. Background technique [0002] In the field of clinical medicine and environmental health monitoring, it is often necessary to monitor the concentration of carbon dioxide in the gas. For example, in clinical operations, it is very important to quickly and accurately determine the position of the endotracheal tube in the process of first aid, resuscitation and anesthesia. Serious harm or even death, the most effective identification method at present is to detect the carbon dioxide in the exhaled breath. In most cases, it is detected by instruments. However, the instruments are expensive and inconvenient to carry and use. There is also a method of detecting the concentration of carbon dioxide in the exhaled breath by means of chemical discoloration i...

Claims

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Application Information

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IPC IPC(8): G01N33/52
CPCG01N33/523
Inventor 刘泊志
Owner 江苏德威兰医疗器械股份有限公司
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